Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883371150> ?p ?o ?g. }
- W2883371150 endingPage "802" @default.
- W2883371150 startingPage "760" @default.
- W2883371150 abstract "Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor of clinical interest as a drug target in various metabolic disorders. PPARα also exhibits marked anti-inflammatory capacities. The first-generation PPARα agonists, the fibrates, have however been hampered by drug-drug interaction issues, statin drop-in, and ill-designed cardiovascular intervention trials. Notwithstanding, understanding the molecular mechanisms by which PPARα works will enable control of its activities as a drug target for metabolic diseases with an underlying inflammatory component. Given its role in reshaping the immune system, the full potential of this nuclear receptor subtype as a versatile drug target with high plasticity becomes increasingly clear, and a novel generation of agonists may pave the way for novel fields of applications." @default.
- W2883371150 created "2018-08-03" @default.
- W2883371150 creator A5000276555 @default.
- W2883371150 creator A5000694609 @default.
- W2883371150 creator A5001127450 @default.
- W2883371150 creator A5029130256 @default.
- W2883371150 creator A5044198492 @default.
- W2883371150 creator A5046462982 @default.
- W2883371150 creator A5068369664 @default.
- W2883371150 date "2018-07-17" @default.
- W2883371150 modified "2023-10-10" @default.
- W2883371150 title "Molecular Actions of PPARα in Lipid Metabolism and Inflammation" @default.
- W2883371150 cites W125300894 @default.
- W2883371150 cites W1445004704 @default.
- W2883371150 cites W1481314844 @default.
- W2883371150 cites W1498355112 @default.
- W2883371150 cites W1523820703 @default.
- W2883371150 cites W1524478189 @default.
- W2883371150 cites W1524910854 @default.
- W2883371150 cites W1526348057 @default.
- W2883371150 cites W1539079080 @default.
- W2883371150 cites W1539647070 @default.
- W2883371150 cites W1544291394 @default.
- W2883371150 cites W1548401583 @default.
- W2883371150 cites W1549577793 @default.
- W2883371150 cites W1567127662 @default.
- W2883371150 cites W1572750670 @default.
- W2883371150 cites W1576936445 @default.
- W2883371150 cites W1587163374 @default.
- W2883371150 cites W1591517987 @default.
- W2883371150 cites W1603786143 @default.
- W2883371150 cites W1608005125 @default.
- W2883371150 cites W1633042224 @default.
- W2883371150 cites W1639924204 @default.
- W2883371150 cites W1643947316 @default.
- W2883371150 cites W1647126819 @default.
- W2883371150 cites W1671834350 @default.
- W2883371150 cites W172609984 @default.
- W2883371150 cites W1833451156 @default.
- W2883371150 cites W1841635074 @default.
- W2883371150 cites W1871383532 @default.
- W2883371150 cites W1871647034 @default.
- W2883371150 cites W1874408158 @default.
- W2883371150 cites W1908444498 @default.
- W2883371150 cites W1933305258 @default.
- W2883371150 cites W1964216244 @default.
- W2883371150 cites W1964485410 @default.
- W2883371150 cites W1965309337 @default.
- W2883371150 cites W1965397552 @default.
- W2883371150 cites W1966168105 @default.
- W2883371150 cites W1967012020 @default.
- W2883371150 cites W1967150290 @default.
- W2883371150 cites W1967189772 @default.
- W2883371150 cites W1969384498 @default.
- W2883371150 cites W1970030711 @default.
- W2883371150 cites W1970298287 @default.
- W2883371150 cites W1970329407 @default.
- W2883371150 cites W1970374778 @default.
- W2883371150 cites W1970651271 @default.
- W2883371150 cites W1972744939 @default.
- W2883371150 cites W1972978588 @default.
- W2883371150 cites W1974658675 @default.
- W2883371150 cites W1974988155 @default.
- W2883371150 cites W1975107195 @default.
- W2883371150 cites W1975717275 @default.
- W2883371150 cites W1975884121 @default.
- W2883371150 cites W1975962309 @default.
- W2883371150 cites W1976959914 @default.
- W2883371150 cites W1977080134 @default.
- W2883371150 cites W1977666051 @default.
- W2883371150 cites W1978039335 @default.
- W2883371150 cites W1978125779 @default.
- W2883371150 cites W1978213355 @default.
- W2883371150 cites W1978380407 @default.
- W2883371150 cites W1978690375 @default.
- W2883371150 cites W1979761686 @default.
- W2883371150 cites W1980248069 @default.
- W2883371150 cites W1980316499 @default.
- W2883371150 cites W1981101682 @default.
- W2883371150 cites W1981918805 @default.
- W2883371150 cites W1982849991 @default.
- W2883371150 cites W1982920909 @default.
- W2883371150 cites W1983498453 @default.
- W2883371150 cites W1983841082 @default.
- W2883371150 cites W1984472867 @default.
- W2883371150 cites W1985683101 @default.
- W2883371150 cites W1988012657 @default.
- W2883371150 cites W1988123744 @default.
- W2883371150 cites W1989036024 @default.
- W2883371150 cites W1990509199 @default.
- W2883371150 cites W1992438813 @default.
- W2883371150 cites W1993607604 @default.
- W2883371150 cites W1995683590 @default.
- W2883371150 cites W1996905851 @default.
- W2883371150 cites W1998699321 @default.
- W2883371150 cites W1999391010 @default.
- W2883371150 cites W1999975112 @default.
- W2883371150 cites W2000017511 @default.