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- W2883375911 abstract "The understanding of bulk level properties and their interrelation with various aspects of formulation development is of prime importance for successful product development. The product development process is very complex, and single variations may lead to a disastrous effect, as it will directly affect the bioavailability and stability of the formulation. The bulk level properties are also affected by interparticle forces which in turn affects the pharmaceutical process and formulation. This chapter expounds the recent advances in understanding the effect of powder properties, particularly particle properties, their influence on interparticle interactions, and eventually on powder bulk behavior. The chapter focuses on developing the rationale for understanding the role of bulk level properties on the actions of solid particles and their effects on the functionality of the dosage form along with powder flowability and compactibility. The rational understanding of the role of processing techniques on the surface and bulk properties and their impacts on the solid bulk behavior is also the scope of this chapter." @default.
- W2883375911 created "2018-08-03" @default.
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- W2883375911 date "2018-01-01" @default.
- W2883375911 modified "2023-10-17" @default.
- W2883375911 title "Bulk Level Properties and its Role in Formulation Development and Processing" @default.
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- W2883375911 doi "https://doi.org/10.1016/b978-0-12-814421-3.00006-3" @default.
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