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- W2883459497 abstract "Although there is no cure for inflammatory bowel disease (IBD), its symptoms can be treated and remission induced using biological medicines, including the anti-TNF (tumour necrosis factor) drug infliximab. Biosimilars of infliximab have been made available in guidelines from the British Society of Gastroenterology and the National Institute for Health and Care Excellence, and they represent a considerable cost-saving opportunity for the NHS. The potential difficulties of switching infliximab to a biosimilar at a hospital can be overcome with a two-step implementation process. Emerging evidence on the factors influencing the variable effectiveness of these therapies is shaping best clinical practice, including studies on anti-TNF trough levels and anti-drug antibodies to infliximab, as well as the use of immunosuppressants. IBD nurse have the specialist knowledge and are in a unique position to measure progress, educate patients and encourage compliance, all of which helps optimise and prolong the effecti..." @default.
- W2883459497 created "2018-08-03" @default.
- W2883459497 creator A5037180571 @default.
- W2883459497 date "2018-07-01" @default.
- W2883459497 modified "2023-09-24" @default.
- W2883459497 title "Biologics and biosimilars in inflammatory bowel disease" @default.
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- W2883459497 doi "https://doi.org/10.12968/npre.2018.16.sup7.14" @default.
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