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- W2883513612 abstract "目的 探讨磁性阿霉素隐形脂质体靶向治疗裸鼠移植性人胃癌的疗效.方法荷人胃癌的裸鼠为动物模型,尾静脉给药,肿瘤部位放置恒定磁场进行磁导向化疗.结果磁性阿霉素隐形脂质体靶向MDL(+)组对人胃癌的移植瘤有显著抑制作用,体积和瘤重抑瘤率分别为71%和70%,显著高于磁性阿霉素隐形脂质体非靶向MDL(-)组(57%、50%)和游离阿霉素D OX组(33%、31%)(P<0.05),空白组细胞凋亡率均低于各实验组,MDL(+)组达 42% ,高于其他各组(P<0.05).实验期间DOX组体重一直未见增加,而MDL(+)组体重平稳增加,且饮食、活动未见明显变化. 结论磁性阿霉素隐形脂质体作为一种新型抗肿瘤药物显示了良好的应用前景。" @default.
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- W2883513612 date "2005-03-25" @default.
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- W2883513612 title "Clinical features and surgical treatment of retroperitoneal Castleman's disease with paraneoplastic pemphigus" @default.
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