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- W2883586223 abstract "A cobalt( III ) complex, [Co(L) 2 ](ClO 4 ) 3 ( 1 ), in which the ligand L was N , N ‐diethyl‐4‐(2,2′:6′,2′′‐terpyridin‐4′‐yl)aniline (L), was synthesized and fully characterized. This new cobalt( III ) complex 1 exhibited selective cytotoxicity against HeLa, T‐24, A549, MGC 80‐3, HepG2, and SK ‐ OV ‐3 cells with IC 50 values in the micromolar range (0.52 – 4.33 μ m ), and it exhibited low cytotoxicity against normal HL ‐7702 cells. The complex 1 was the most potent against the T‐24 cells. It was found that 1 could cause the cell cycle arrest in G1 phase, and it exerted its antitumor activity mainly via disruption of mitochondrial function." @default.
- W2883586223 created "2018-08-03" @default.
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- W2883586223 date "2018-09-21" @default.
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- W2883586223 title "Synthesis, Characterization, and Cytotoxicity of the Cobalt (III) Complex with <i>N</i> ,<i>N</i> -Diethyl-4-(2,2′:6′,2′′-terpyridin-4′-yl)aniline" @default.
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- W2883586223 doi "https://doi.org/10.1002/cbdv.201800215" @default.
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