FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883630285> ?p ?o ?g. }

• W2883630285 endingPage "1299" @default.
• W2883630285 startingPage "1289" @default.
• W2883630285 abstract "Febuxostat is a potent non-purine selective xanthine oxidase inhibitor approved by the FDA in 2009 for management of hyperuricemia in people with gout. Areas covered: The authors summarize the pre-clinical studies and pivotal randomized controlled trials of febuxostat when used as a treatment for hyperuricaemia in gout Expert opinion: Febuxostat has clinical efficacy in serum urate lowering, and long-term use leads to improved outcomes such as gout flare frequency and tophus burden. Recently published post-approval placebo-controlled trials have demonstrated urate-lowering efficacy and safety of febuxostat in patients with chronic kidney disease, and reduced frequency of gout flares in people with early onset of gout. In November 2017, the FDA issued a drug safety communication based on the preliminary results of the CARES trial. This cardiovascular safety study of 6190 patients with gout and established cardiovascular disease comparing febuxostat and allopurinol showed no difference in the primary endpoint (a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or unstable angina with urgent revascularization), but did report higher all-cause mortality (hazard ratio 1.22) and cardiovascular mortality (hazard ratio 1.34) with febuxostat. Based on currently available data, it seems likely that allopurinol, rather than febuxostat, will remain first line urate-lowering therapy for people with gout." @default.
• W2883630285 created "2018-08-03" @default.
• W2883630285 creator A5008272034 @default.
• W2883630285 creator A5086285989 @default.
• W2883630285 date "2018-07-19" @default.
• W2883630285 modified "2023-10-14" @default.
• W2883630285 title "Febuxostat for the treatment of hyperuricaemia in gout" @default.
• W2883630285 cites W1546053815 @default.
• W2883630285 cites W1561987315 @default.
• W2883630285 cites W1662589166 @default.
• W2883630285 cites W1964439201 @default.
• W2883630285 cites W1986188871 @default.
• W2883630285 cites W1988110621 @default.
• W2883630285 cites W1990212288 @default.
• W2883630285 cites W2000166571 @default.
• W2883630285 cites W2003407110 @default.
• W2883630285 cites W2020033798 @default.
• W2883630285 cites W2024758091 @default.
• W2883630285 cites W2073496185 @default.
• W2883630285 cites W2076052958 @default.
• W2883630285 cites W2106983312 @default.
• W2883630285 cites W2107225963 @default.
• W2883630285 cites W2108262590 @default.
• W2883630285 cites W2111237091 @default.
• W2883630285 cites W2114365596 @default.
• W2883630285 cites W2121255483 @default.
• W2883630285 cites W2131167925 @default.
• W2883630285 cites W2134743466 @default.
• W2883630285 cites W2145066076 @default.
• W2883630285 cites W2149623494 @default.
• W2883630285 cites W2150408471 @default.
• W2883630285 cites W2151706655 @default.
• W2883630285 cites W2156131531 @default.
• W2883630285 cites W2171311050 @default.
• W2883630285 cites W2282083919 @default.
• W2883630285 cites W2299937634 @default.
• W2883630285 cites W2301340671 @default.
• W2883630285 cites W2335302945 @default.
• W2883630285 cites W2514912829 @default.
• W2883630285 cites W2552033401 @default.
• W2883630285 cites W2567327386 @default.
• W2883630285 cites W2622335202 @default.
• W2883630285 cites W2760493179 @default.
• W2883630285 cites W2761615158 @default.
• W2883630285 cites W2765452810 @default.
• W2883630285 cites W2785995518 @default.
• W2883630285 cites W2793103574 @default.
• W2883630285 cites W4242080988 @default.
• W2883630285 doi "https://doi.org/10.1080/14656566.2018.1498842" @default.
• W2883630285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30024787" @default.
• W2883630285 hasPublicationYear "2018" @default.
• W2883630285 type Work @default.
• W2883630285 sameAs 2883630285 @default.
• W2883630285 citedByCount "18" @default.
• W2883630285 countsByYear W28836302852018 @default.
• W2883630285 countsByYear W28836302852019 @default.
• W2883630285 countsByYear W28836302852020 @default.
• W2883630285 countsByYear W28836302852021 @default.
• W2883630285 countsByYear W28836302852022 @default.
• W2883630285 countsByYear W28836302852023 @default.
• W2883630285 crossrefType "journal-article" @default.
• W2883630285 hasAuthorship W2883630285A5008272034 @default.
• W2883630285 hasAuthorship W2883630285A5086285989 @default.
• W2883630285 hasConcept C126322002 @default.
• W2883630285 hasConcept C181199279 @default.
• W2883630285 hasConcept C185592680 @default.
• W2883630285 hasConcept C2777820942 @default.
• W2883630285 hasConcept C2778102346 @default.
• W2883630285 hasConcept C2779721657 @default.
• W2883630285 hasConcept C2779881121 @default.
• W2883630285 hasConcept C2780261098 @default.
• W2883630285 hasConcept C2780402116 @default.
• W2883630285 hasConcept C2780932893 @default.
• W2883630285 hasConcept C535046627 @default.
• W2883630285 hasConcept C55493867 @default.
• W2883630285 hasConcept C71924100 @default.
• W2883630285 hasConcept C98274493 @default.
• W2883630285 hasConceptScore W2883630285C126322002 @default.
• W2883630285 hasConceptScore W2883630285C181199279 @default.
• W2883630285 hasConceptScore W2883630285C185592680 @default.
• W2883630285 hasConceptScore W2883630285C2777820942 @default.
• W2883630285 hasConceptScore W2883630285C2778102346 @default.
• W2883630285 hasConceptScore W2883630285C2779721657 @default.
• W2883630285 hasConceptScore W2883630285C2779881121 @default.
• W2883630285 hasConceptScore W2883630285C2780261098 @default.
• W2883630285 hasConceptScore W2883630285C2780402116 @default.
• W2883630285 hasConceptScore W2883630285C2780932893 @default.
• W2883630285 hasConceptScore W2883630285C535046627 @default.
• W2883630285 hasConceptScore W2883630285C55493867 @default.
• W2883630285 hasConceptScore W2883630285C71924100 @default.
• W2883630285 hasConceptScore W2883630285C98274493 @default.
• W2883630285 hasIssue "11" @default.
• W2883630285 hasLocation W28836302851 @default.
• W2883630285 hasLocation W28836302852 @default.
• W2883630285 hasOpenAccess W2883630285 @default.
• W2883630285 hasPrimaryLocation W28836302851 @default.
• W2883630285 hasRelatedWork W192509142 @default.
• W2883630285 hasRelatedWork W1966731608 @default.

• next