Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883741383> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2883741383 abstract "Amac: Gunluk yasamin bir parcasi haline gelen stres, vucudun dengesini bozarak pek cok hastaliga neden olur. Biz de bu calismada, kronik strese sebep olan faktorlere maruz kalindiginda bobrekte meydana gelebilecek olasi yapisal degisiklikleri arastirmayi amacladik. Gerec ve Yontem: Bu calismada 12 adet Sprague Dawley cinsi yetiskin erkek sican kullanildi. Sicanlar rastgele kontrol (n=6) ve stres (n=6) grubu olarak ikiye ayrildiktan sonra, stres grubundakilere 4 hafta boyunca “beklenmedik kronik hafif stres” protokolu uygulandi. Deneyin sonunda anestezisi altinda feda edilen butun sicanlarin bobrekleri cikarildi ve derhal “suya daldirma yontemi” ile hacimleri olculdu. Bobrekler rutin histolojik islemleri takiben, histopatolojik degerlendirme icin isik mikroskobunda incelendi. Bulgular: Stres grubundaki sicanlarin bobrek hacimlerinin (0,90 ± 0,096 ml) kontrol grubundakilerin bobrek hacimlerine (1,075 ± 0,106 ml) kiyasla onemli duzeyde azalmis oldugu ( p <0,05; independent samples t test) tespit edildi. Stres grubu bobreklerinin isik mikroskobik degerlendirmesinde, nefron tubullerinin epitelinde nekrotik dejenerasyon ve dokulmeler saptandi. Proksimal ve distal tubullerin epitelinde, yer yer hucresel parcalanma ve tubul duvar butunlugunun bozulmasi ile sonuclanan sitoplazmik sisme ve hucresel vakuollesmeler belirgindi. Henle kulpunda da lumende bariz dilatasyonlar ve epitelde nekrotik degisiklikler tespit edildi. Ilaveten glomerullerde buzusme ve Bowman boslugunda genislemeler gozlendi. Sonuc: Elde edilen bulgulara dayanarak, kronik stresin bobrekte buyuk olasilikla fonksiyonel yetersizlige yol acacak glomeruler hasara ve tubul epitel hucrelerinde zedelenmeye sebep oldugu dusunuldu." @default.
- W2883741383 created "2018-08-03" @default.
- W2883741383 creator A5008071752 @default.
- W2883741383 creator A5043084498 @default.
- W2883741383 creator A5062646844 @default.
- W2883741383 date "2018-01-04" @default.
- W2883741383 modified "2023-10-16" @default.
- W2883741383 title "Kronik Stres ve Böbrek: Sıçan Modeli Üzerinde Morfometrik ve Histopatolojik Çalışma" @default.
- W2883741383 cites W1547358456 @default.
- W2883741383 cites W1937168413 @default.
- W2883741383 cites W1966745469 @default.
- W2883741383 cites W1971639265 @default.
- W2883741383 cites W1975252975 @default.
- W2883741383 cites W1977430165 @default.
- W2883741383 cites W1982923975 @default.
- W2883741383 cites W1984829837 @default.
- W2883741383 cites W1991352662 @default.
- W2883741383 cites W1992390260 @default.
- W2883741383 cites W1993288994 @default.
- W2883741383 cites W1996680733 @default.
- W2883741383 cites W2001259350 @default.
- W2883741383 cites W2008741015 @default.
- W2883741383 cites W2009281912 @default.
- W2883741383 cites W2017275974 @default.
- W2883741383 cites W2017933369 @default.
- W2883741383 cites W2019174770 @default.
- W2883741383 cites W2021650173 @default.
- W2883741383 cites W2024963329 @default.
- W2883741383 cites W2051854550 @default.
- W2883741383 cites W2058303679 @default.
- W2883741383 cites W2059467226 @default.
- W2883741383 cites W2062655222 @default.
- W2883741383 cites W2063625099 @default.
- W2883741383 cites W2066457796 @default.
- W2883741383 cites W2072357686 @default.
- W2883741383 cites W2074207584 @default.
- W2883741383 cites W2075960777 @default.
- W2883741383 cites W2078601501 @default.
- W2883741383 cites W2083578200 @default.
- W2883741383 cites W2084652045 @default.
- W2883741383 cites W2085272519 @default.
- W2883741383 cites W2089809656 @default.
- W2883741383 cites W2097529540 @default.
- W2883741383 cites W2102634039 @default.
- W2883741383 cites W2111123038 @default.
- W2883741383 cites W2117319789 @default.
- W2883741383 cites W2120849943 @default.
- W2883741383 cites W2122252112 @default.
- W2883741383 cites W2130198046 @default.
- W2883741383 cites W2136128927 @default.
- W2883741383 cites W2139720861 @default.
- W2883741383 cites W2158422852 @default.
- W2883741383 cites W2159733957 @default.
- W2883741383 cites W2276895878 @default.
- W2883741383 cites W2325508518 @default.
- W2883741383 cites W2339760129 @default.
- W2883741383 cites W2416791589 @default.
- W2883741383 cites W2420065946 @default.
- W2883741383 doi "https://doi.org/10.31832/smj.366673" @default.
- W2883741383 hasPublicationYear "2018" @default.
- W2883741383 type Work @default.
- W2883741383 sameAs 2883741383 @default.
- W2883741383 citedByCount "0" @default.
- W2883741383 crossrefType "journal-article" @default.
- W2883741383 hasAuthorship W2883741383A5008071752 @default.
- W2883741383 hasAuthorship W2883741383A5043084498 @default.
- W2883741383 hasAuthorship W2883741383A5062646844 @default.
- W2883741383 hasBestOaLocation W28837413831 @default.
- W2883741383 hasConcept C16005928 @default.
- W2883741383 hasConcept C29456083 @default.
- W2883741383 hasConcept C556039675 @default.
- W2883741383 hasConcept C71924100 @default.
- W2883741383 hasConceptScore W2883741383C16005928 @default.
- W2883741383 hasConceptScore W2883741383C29456083 @default.
- W2883741383 hasConceptScore W2883741383C556039675 @default.
- W2883741383 hasConceptScore W2883741383C71924100 @default.
- W2883741383 hasLocation W28837413831 @default.
- W2883741383 hasLocation W28837413832 @default.
- W2883741383 hasOpenAccess W2883741383 @default.
- W2883741383 hasPrimaryLocation W28837413831 @default.
- W2883741383 hasRelatedWork W1506200166 @default.
- W2883741383 hasRelatedWork W1995515455 @default.
- W2883741383 hasRelatedWork W2048182022 @default.
- W2883741383 hasRelatedWork W2080531066 @default.
- W2883741383 hasRelatedWork W2748952813 @default.
- W2883741383 hasRelatedWork W2899084033 @default.
- W2883741383 hasRelatedWork W3031052312 @default.
- W2883741383 hasRelatedWork W3032375762 @default.
- W2883741383 hasRelatedWork W3108674512 @default.
- W2883741383 hasRelatedWork W4297184974 @default.
- W2883741383 isParatext "false" @default.
- W2883741383 isRetracted "false" @default.
- W2883741383 magId "2883741383" @default.
- W2883741383 workType "article" @default.