Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883753668> ?p ?o ?g. }
- W2883753668 abstract "Chronic viral hepatitis infections are a major public health concern, with an estimated 290 million individuals infected with hepatitis B virus (HBV) globally. This virus has been a passenger in human populations for 30,000 years, and remains highly prevalent in some settings. In order for this endemic pathogen to persist, viral adaptation to host immune responses is pre-requisite. Here we focus on the interplay between HBV infection and the CD8+ T cell response. We present the evidence that CD8+ T cells play an important role in control of chronic HBV infection and that the selective pressure imposed on HBV through evasion of these immune responses can potentially influence viral diversity, chronicity, and the outcome of infection. Understanding the nature and mechanisms of HBV evolution and persistence could shed light on differential disease outcomes, including cirrhosis and hepatocellular carcinoma, and help reach the goal of global HBV elimination by guiding the design of new strategies, including vaccines and therapeutics." @default.
- W2883753668 created "2018-08-03" @default.
- W2883753668 creator A5029546143 @default.
- W2883753668 creator A5054812318 @default.
- W2883753668 creator A5062773984 @default.
- W2883753668 creator A5063851564 @default.
- W2883753668 creator A5090088811 @default.
- W2883753668 date "2018-07-16" @default.
- W2883753668 modified "2023-10-17" @default.
- W2883753668 title "Hepatitis B Virus Adaptation to the CD8+ T Cell Response: Consequences for Host and Pathogen" @default.
- W2883753668 cites W1424006447 @default.
- W2883753668 cites W1543067125 @default.
- W2883753668 cites W1817144267 @default.
- W2883753668 cites W1844510062 @default.
- W2883753668 cites W1876100835 @default.
- W2883753668 cites W1899355388 @default.
- W2883753668 cites W1937293717 @default.
- W2883753668 cites W1940739348 @default.
- W2883753668 cites W1968979436 @default.
- W2883753668 cites W1969093502 @default.
- W2883753668 cites W1972194314 @default.
- W2883753668 cites W1974765151 @default.
- W2883753668 cites W1978385313 @default.
- W2883753668 cites W1978436252 @default.
- W2883753668 cites W1978551768 @default.
- W2883753668 cites W1978656930 @default.
- W2883753668 cites W1983086160 @default.
- W2883753668 cites W1983251878 @default.
- W2883753668 cites W1983681889 @default.
- W2883753668 cites W1987828763 @default.
- W2883753668 cites W1995617158 @default.
- W2883753668 cites W1997047331 @default.
- W2883753668 cites W1997751261 @default.
- W2883753668 cites W2000307707 @default.
- W2883753668 cites W2001976371 @default.
- W2883753668 cites W2003818956 @default.
- W2883753668 cites W2006774237 @default.
- W2883753668 cites W2012774039 @default.
- W2883753668 cites W2013815517 @default.
- W2883753668 cites W2014800345 @default.
- W2883753668 cites W2015113497 @default.
- W2883753668 cites W2015804728 @default.
- W2883753668 cites W2017312443 @default.
- W2883753668 cites W2017572742 @default.
- W2883753668 cites W2017725829 @default.
- W2883753668 cites W2020860190 @default.
- W2883753668 cites W2022225387 @default.
- W2883753668 cites W2023967363 @default.
- W2883753668 cites W2025283567 @default.
- W2883753668 cites W2032152239 @default.
- W2883753668 cites W2033239466 @default.
- W2883753668 cites W2037566195 @default.
- W2883753668 cites W2045551237 @default.
- W2883753668 cites W2045723524 @default.
- W2883753668 cites W2047928642 @default.
- W2883753668 cites W2048056516 @default.
- W2883753668 cites W2049102021 @default.
- W2883753668 cites W2050626875 @default.
- W2883753668 cites W2051589473 @default.
- W2883753668 cites W2053695022 @default.
- W2883753668 cites W2057567758 @default.
- W2883753668 cites W205825863 @default.
- W2883753668 cites W2060672402 @default.
- W2883753668 cites W2063059443 @default.
- W2883753668 cites W2063695575 @default.
- W2883753668 cites W2064294645 @default.
- W2883753668 cites W2064883226 @default.
- W2883753668 cites W2065951980 @default.
- W2883753668 cites W2070871133 @default.
- W2883753668 cites W2071911570 @default.
- W2883753668 cites W2075106941 @default.
- W2883753668 cites W2079316096 @default.
- W2883753668 cites W2079564326 @default.
- W2883753668 cites W2079944166 @default.
- W2883753668 cites W2081861662 @default.
- W2883753668 cites W2084152099 @default.
- W2883753668 cites W2085256975 @default.
- W2883753668 cites W2085569843 @default.
- W2883753668 cites W2088229370 @default.
- W2883753668 cites W2091587948 @default.
- W2883753668 cites W2096094255 @default.
- W2883753668 cites W2096966773 @default.
- W2883753668 cites W2097150100 @default.
- W2883753668 cites W2098459535 @default.
- W2883753668 cites W2098512025 @default.
- W2883753668 cites W2099180271 @default.
- W2883753668 cites W2100363854 @default.
- W2883753668 cites W2100587714 @default.
- W2883753668 cites W2105550963 @default.
- W2883753668 cites W2105607250 @default.
- W2883753668 cites W2106908798 @default.
- W2883753668 cites W2107186721 @default.
- W2883753668 cites W2109130469 @default.
- W2883753668 cites W2109645964 @default.
- W2883753668 cites W2109941665 @default.
- W2883753668 cites W2110735100 @default.
- W2883753668 cites W2112159305 @default.
- W2883753668 cites W2115969723 @default.
- W2883753668 cites W2116364705 @default.
- W2883753668 cites W2117905220 @default.