FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883858112> ?p ?o ?g. }

• W2883858112 endingPage "805" @default.
• W2883858112 startingPage "797" @default.
• W2883858112 abstract "Anaemia reduces the efficacy of chemotherapy in gastric cancer. However, it has not been studied in oesophageal cancer. We investigated whether anaemia impacts on survival and the efficacy of chemotherapy, in adenocarcinoma of the oesophagus for those undergoing neoadjuvant chemotherapy and then surgical resection.This prospective study included 268 patients who received neoadjuvant chemotherapy for oesophageal adenocarcinoma. Patient clinical data as well as Mandard's tumor regression grading (TRG), haemoglobin pre-chemotherapy and during the chemotherapy were compiled. The association between anaemia and TRG was tested using Chi-squared analysis, whilst survival outcomes were investigated by Kaplan-Meier and Cox regression.One hundred participants were anaemic before chemotherapy whilst 224 were anaemic during chemotherapy cycles. Survival analyses found a significant association between lower haemoglobin levels and decreased overall survival (P=0.048). Comparing those without anaemia against those with moderate -severe anaemia (<10.9 g/dL) found a statistically significant association in overall survival (P=0.026). Multivariate cox regression showed those with anaemia were statistically more likely to have decreased overall survival (HR 1.735, 95% CI, 1.050-2.867, P=0.032). No statistical association was seen between those with pre-chemotherapy anaemia and TRG (OR 0.675, 95% CI, 0.420-1.161, P=0.130) or those with anytime anaemia (OR 0.881, 95% CI, 0.406-1.914, P=0.931).These results suggest that anaemia is associated with poorer overall survival time, with lower haemoglobin levels reducing prognosis. However, there does not appear to be an association between anaemia and chemotherapy response in oesophageal adenocarcinoma." @default.
• W2883858112 created "2018-08-03" @default.
• W2883858112 creator A5000554874 @default.
• W2883858112 creator A5005673379 @default.
• W2883858112 creator A5025138815 @default.
• W2883858112 creator A5042424551 @default.
• W2883858112 creator A5079227041 @default.
• W2883858112 date "2018-10-01" @default.
• W2883858112 modified "2023-10-07" @default.
• W2883858112 title "Anaemia and its effects on tumour regression grade and survival following chemotherapy in adenocarcinoma of the oesophagus" @default.
• W2883858112 cites W1757407923 @default.
• W2883858112 cites W1910935083 @default.
• W2883858112 cites W1971259059 @default.
• W2883858112 cites W1977468182 @default.
• W2883858112 cites W2024159843 @default.
• W2883858112 cites W2032819193 @default.
• W2883858112 cites W2037660795 @default.
• W2883858112 cites W2039258873 @default.
• W2883858112 cites W2040446578 @default.
• W2883858112 cites W2063163198 @default.
• W2883858112 cites W2084486398 @default.
• W2883858112 cites W2092510654 @default.
• W2883858112 cites W2112645200 @default.
• W2883858112 cites W2119255644 @default.
• W2883858112 cites W2128328462 @default.
• W2883858112 cites W2131630923 @default.
• W2883858112 cites W2151029652 @default.
• W2883858112 cites W2155104309 @default.
• W2883858112 cites W2159955722 @default.
• W2883858112 cites W2161395451 @default.
• W2883858112 cites W2184701683 @default.
• W2883858112 cites W2190253128 @default.
• W2883858112 cites W2409684739 @default.
• W2883858112 cites W2414484987 @default.
• W2883858112 cites W2438786933 @default.
• W2883858112 cites W2490318515 @default.
• W2883858112 cites W4247774426 @default.
• W2883858112 doi "https://doi.org/10.21037/jgo.2018.06.05" @default.
• W2883858112 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6219986" @default.
• W2883858112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30505578" @default.
• W2883858112 hasPublicationYear "2018" @default.
• W2883858112 type Work @default.
• W2883858112 sameAs 2883858112 @default.
• W2883858112 citedByCount "2" @default.
• W2883858112 countsByYear W28838581122020 @default.
• W2883858112 countsByYear W28838581122023 @default.
• W2883858112 crossrefType "journal-article" @default.
• W2883858112 hasAuthorship W2883858112A5000554874 @default.
• W2883858112 hasAuthorship W2883858112A5005673379 @default.
• W2883858112 hasAuthorship W2883858112A5025138815 @default.
• W2883858112 hasAuthorship W2883858112A5042424551 @default.
• W2883858112 hasAuthorship W2883858112A5079227041 @default.
• W2883858112 hasBestOaLocation W28838581122 @default.
• W2883858112 hasConcept C10515644 @default.
• W2883858112 hasConcept C121608353 @default.
• W2883858112 hasConcept C126322002 @default.
• W2883858112 hasConcept C127413603 @default.
• W2883858112 hasConcept C141071460 @default.
• W2883858112 hasConcept C143998085 @default.
• W2883858112 hasConcept C147176958 @default.
• W2883858112 hasConcept C2776694085 @default.
• W2883858112 hasConcept C2777286243 @default.
• W2883858112 hasConcept C2781182431 @default.
• W2883858112 hasConcept C50382708 @default.
• W2883858112 hasConcept C71924100 @default.
• W2883858112 hasConcept C90924648 @default.
• W2883858112 hasConceptScore W2883858112C10515644 @default.
• W2883858112 hasConceptScore W2883858112C121608353 @default.
• W2883858112 hasConceptScore W2883858112C126322002 @default.
• W2883858112 hasConceptScore W2883858112C127413603 @default.
• W2883858112 hasConceptScore W2883858112C141071460 @default.
• W2883858112 hasConceptScore W2883858112C143998085 @default.
• W2883858112 hasConceptScore W2883858112C147176958 @default.
• W2883858112 hasConceptScore W2883858112C2776694085 @default.
• W2883858112 hasConceptScore W2883858112C2777286243 @default.
• W2883858112 hasConceptScore W2883858112C2781182431 @default.
• W2883858112 hasConceptScore W2883858112C50382708 @default.
• W2883858112 hasConceptScore W2883858112C71924100 @default.
• W2883858112 hasConceptScore W2883858112C90924648 @default.
• W2883858112 hasIssue "5" @default.
• W2883858112 hasLocation W28838581121 @default.
• W2883858112 hasLocation W28838581122 @default.
• W2883858112 hasLocation W28838581123 @default.
• W2883858112 hasLocation W28838581124 @default.
• W2883858112 hasOpenAccess W2883858112 @default.
• W2883858112 hasPrimaryLocation W28838581121 @default.
• W2883858112 hasRelatedWork W1972849980 @default.
• W2883858112 hasRelatedWork W2080671488 @default.
• W2883858112 hasRelatedWork W2337677096 @default.
• W2883858112 hasRelatedWork W2569474543 @default.
• W2883858112 hasRelatedWork W2622495883 @default.
• W2883858112 hasRelatedWork W3011827526 @default.
• W2883858112 hasRelatedWork W3012824765 @default.
• W2883858112 hasRelatedWork W4214893797 @default.
• W2883858112 hasRelatedWork W4285594075 @default.
• W2883858112 hasRelatedWork W4312772167 @default.
• W2883858112 hasVolume "9" @default.
• W2883858112 isParatext "false" @default.

• next