FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2883996810> ?p ?o ?g. }

• W2883996810 abstract "ABSTRACT Cap analysis of gene expression (CAGE) is a methodology for genome-wide quantitative mapping of mRNA 5’ends to precisely capture transcription start sites at a single nucleotide resolution. In combination with high-throughput sequencing, CAGE has revolutionized our understanding of rules of transcription initiation, led to discovery of new core promoter sequence features and discovered transcription initiation at enhancers genome-wide. The biggest limitation of CAGE is that even the most recently improved version (nAnT-iCAGE) still requires large amounts of total cellular RNA (5 micrograms), preventing its application to scarce biological samples such as those from early embryonic development or rare cell types. Here, we present SLIC-CAGE, a Super-Low Input Carrier-CAGE approach to capture 5’ends of RNA polymerase II transcripts from as little as 5-10 ng of total RNA. The dramatic increase in sensitivity is achieved by specially designed, selectively degradable carrier RNA. We demonstrate the ability of SLIC-CAGE to generate data for genome-wide promoterome with 1000-fold less material than required by existing CAGE methods by generating a complex, high quality library from mouse embryonic day (E) 11.5 primordial germ cells." @default.
• W2883996810 created "2018-08-03" @default.
• W2883996810 creator A5006320247 @default.
• W2883996810 creator A5008085628 @default.
• W2883996810 creator A5031980265 @default.
• W2883996810 creator A5052661284 @default.
• W2883996810 creator A5065332242 @default.
• W2883996810 creator A5072131150 @default.
• W2883996810 creator A5084805363 @default.
• W2883996810 date "2018-07-15" @default.
• W2883996810 modified "2023-09-24" @default.
• W2883996810 title "SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA" @default.
• W2883996810 cites W10777826 @default.
• W2883996810 cites W1965100590 @default.
• W2883996810 cites W1981862938 @default.
• W2883996810 cites W1986223165 @default.
• W2883996810 cites W1986408963 @default.
• W2883996810 cites W1996431759 @default.
• W2883996810 cites W1996507133 @default.
• W2883996810 cites W2015845481 @default.
• W2883996810 cites W2020637859 @default.
• W2883996810 cites W2025438502 @default.
• W2883996810 cites W2029873987 @default.
• W2883996810 cites W2041677964 @default.
• W2883996810 cites W2055720906 @default.
• W2883996810 cites W2057692691 @default.
• W2883996810 cites W2077173342 @default.
• W2883996810 cites W2083073732 @default.
• W2883996810 cites W2097920884 @default.
• W2883996810 cites W2099143842 @default.
• W2883996810 cites W2102920878 @default.
• W2883996810 cites W2108234281 @default.
• W2883996810 cites W2114703458 @default.
• W2883996810 cites W2121116352 @default.
• W2883996810 cites W2124220434 @default.
• W2883996810 cites W2131356974 @default.
• W2883996810 cites W2132047191 @default.
• W2883996810 cites W2132672675 @default.
• W2883996810 cites W2133990340 @default.
• W2883996810 cites W2138237282 @default.
• W2883996810 cites W2142587958 @default.
• W2883996810 cites W2147740890 @default.
• W2883996810 cites W2150904790 @default.
• W2883996810 cites W2155530972 @default.
• W2883996810 cites W2160051211 @default.
• W2883996810 cites W2170698318 @default.
• W2883996810 cites W2170830174 @default.
• W2883996810 cites W2259938310 @default.
• W2883996810 cites W2274378441 @default.
• W2883996810 cites W2306458578 @default.
• W2883996810 cites W2409451325 @default.
• W2883996810 cites W2464717012 @default.
• W2883996810 cites W2586790218 @default.
• W2883996810 cites W2602135828 @default.
• W2883996810 cites W2750857187 @default.
• W2883996810 cites W2770378609 @default.
• W2883996810 cites W2789804929 @default.
• W2883996810 cites W2802765514 @default.
• W2883996810 cites W2807138843 @default.
• W2883996810 cites W2952109315 @default.
• W2883996810 cites W4230096730 @default.
• W2883996810 cites W798940297 @default.
• W2883996810 doi "https://doi.org/10.1101/368795" @default.
• W2883996810 hasPublicationYear "2018" @default.
• W2883996810 type Work @default.
• W2883996810 sameAs 2883996810 @default.
• W2883996810 citedByCount "0" @default.
• W2883996810 crossrefType "posted-content" @default.
• W2883996810 hasAuthorship W2883996810A5006320247 @default.
• W2883996810 hasAuthorship W2883996810A5008085628 @default.
• W2883996810 hasAuthorship W2883996810A5031980265 @default.
• W2883996810 hasAuthorship W2883996810A5052661284 @default.
• W2883996810 hasAuthorship W2883996810A5065332242 @default.
• W2883996810 hasAuthorship W2883996810A5072131150 @default.
• W2883996810 hasAuthorship W2883996810A5084805363 @default.
• W2883996810 hasBestOaLocation W28839968101 @default.
• W2883996810 hasConcept C101762097 @default.
• W2883996810 hasConcept C104317684 @default.
• W2883996810 hasConcept C111936080 @default.
• W2883996810 hasConcept C114614502 @default.
• W2883996810 hasConcept C138885662 @default.
• W2883996810 hasConcept C141231307 @default.
• W2883996810 hasConcept C150194340 @default.
• W2883996810 hasConcept C153911025 @default.
• W2883996810 hasConcept C160272327 @default.
• W2883996810 hasConcept C179926584 @default.
• W2883996810 hasConcept C2776449523 @default.
• W2883996810 hasConcept C33923547 @default.
• W2883996810 hasConcept C41895202 @default.
• W2883996810 hasConcept C54355233 @default.
• W2883996810 hasConcept C64350747 @default.
• W2883996810 hasConcept C67705224 @default.
• W2883996810 hasConcept C70721500 @default.
• W2883996810 hasConcept C86803240 @default.
• W2883996810 hasConceptScore W2883996810C101762097 @default.
• W2883996810 hasConceptScore W2883996810C104317684 @default.
• W2883996810 hasConceptScore W2883996810C111936080 @default.
• W2883996810 hasConceptScore W2883996810C114614502 @default.
• W2883996810 hasConceptScore W2883996810C138885662 @default.
• W2883996810 hasConceptScore W2883996810C141231307 @default.

• next