Matches in SemOpenAlex for { <https://semopenalex.org/work/W2884156795> ?p ?o ?g. }
- W2884156795 abstract "Abstract Magnetic resonance (MR) imaging is a powerful technique for non-invasive in - vivo imaging of the human brain. We employed a recently validated method for robust cross-sectional and longitudinal segmentation of MR brain images from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Specifically, we segmented 5074 MR brain images into 138 anatomical regions and extracted time-point specific structural volumes and volume change during follow-up intervals of 12 or 24 months. We assessed the extracted biomarkers by determining their power to predict diagnostic classification and by comparing atrophy rates to published meta-studies. The approach enables comprehensive analysis of structural changes within the whole brain. The discriminative power of individual biomarkers (volumes/atrophy rates) is on par with results published by other groups. We publish all quality-checked brain masks, structural segmentations, and extracted biomarkers along with this article. We further share the methodology for brain extraction (pincram) and segmentation (MALPEM, MALPEM4D) as open source projects with the community. The identified biomarkers hold great potential for deeper analysis, and the validated methodology can readily be applied to other imaging cohorts." @default.
- W2884156795 created "2018-08-03" @default.
- W2884156795 creator A5006461848 @default.
- W2884156795 creator A5011834074 @default.
- W2884156795 creator A5016912926 @default.
- W2884156795 creator A5056128187 @default.
- W2884156795 creator A5084126057 @default.
- W2884156795 date "2018-07-26" @default.
- W2884156795 modified "2023-10-11" @default.
- W2884156795 title "Structural brain imaging in Alzheimer’s disease and mild cognitive impairment: biomarker analysis and shared morphometry database" @default.
- W2884156795 cites W1434354835 @default.
- W2884156795 cites W1594041518 @default.
- W2884156795 cites W1817986502 @default.
- W2884156795 cites W1838825000 @default.
- W2884156795 cites W1872034074 @default.
- W2884156795 cites W1963847477 @default.
- W2884156795 cites W1976154578 @default.
- W2884156795 cites W1979024706 @default.
- W2884156795 cites W1980872192 @default.
- W2884156795 cites W1982132176 @default.
- W2884156795 cites W1992252533 @default.
- W2884156795 cites W1994694505 @default.
- W2884156795 cites W2000716207 @default.
- W2884156795 cites W2001648635 @default.
- W2884156795 cites W2004293194 @default.
- W2884156795 cites W2014105136 @default.
- W2884156795 cites W2015513982 @default.
- W2884156795 cites W2015629132 @default.
- W2884156795 cites W2019161608 @default.
- W2884156795 cites W2020281498 @default.
- W2884156795 cites W2021404243 @default.
- W2884156795 cites W2028739995 @default.
- W2884156795 cites W2038003677 @default.
- W2884156795 cites W2041796053 @default.
- W2884156795 cites W2049546272 @default.
- W2884156795 cites W2052742260 @default.
- W2884156795 cites W2056898461 @default.
- W2884156795 cites W2057332541 @default.
- W2884156795 cites W2066839705 @default.
- W2884156795 cites W2072188503 @default.
- W2884156795 cites W2078998718 @default.
- W2884156795 cites W2079502798 @default.
- W2884156795 cites W2084258254 @default.
- W2884156795 cites W2087159877 @default.
- W2884156795 cites W2090758627 @default.
- W2884156795 cites W2093092963 @default.
- W2884156795 cites W2096570098 @default.
- W2884156795 cites W2101807845 @default.
- W2884156795 cites W2102508963 @default.
- W2884156795 cites W2104384019 @default.
- W2884156795 cites W2105037799 @default.
- W2884156795 cites W2106931873 @default.
- W2884156795 cites W2107026277 @default.
- W2884156795 cites W2110759468 @default.
- W2884156795 cites W2111913931 @default.
- W2884156795 cites W2112398095 @default.
- W2884156795 cites W2117340355 @default.
- W2884156795 cites W2119000771 @default.
- W2884156795 cites W2119848633 @default.
- W2884156795 cites W2129497119 @default.
- W2884156795 cites W2129965408 @default.
- W2884156795 cites W2135011268 @default.
- W2884156795 cites W2136573752 @default.
- W2884156795 cites W2136579519 @default.
- W2884156795 cites W2146828973 @default.
- W2884156795 cites W2148157540 @default.
- W2884156795 cites W2149128281 @default.
- W2884156795 cites W2151800036 @default.
- W2884156795 cites W2153171432 @default.
- W2884156795 cites W2153635508 @default.
- W2884156795 cites W2154123014 @default.
- W2884156795 cites W2160034813 @default.
- W2884156795 cites W2162333503 @default.
- W2884156795 cites W2164592637 @default.
- W2884156795 cites W2168283959 @default.
- W2884156795 cites W2171051269 @default.
- W2884156795 cites W2171225117 @default.
- W2884156795 cites W2171723438 @default.
- W2884156795 cites W2171831801 @default.
- W2884156795 cites W2179914359 @default.
- W2884156795 cites W2190734858 @default.
- W2884156795 cites W2323681028 @default.
- W2884156795 cites W2337565256 @default.
- W2884156795 cites W2340547861 @default.
- W2884156795 cites W2341143068 @default.
- W2884156795 cites W2471830986 @default.
- W2884156795 cites W2559177759 @default.
- W2884156795 cites W2570375830 @default.
- W2884156795 cites W2577478840 @default.
- W2884156795 cites W2593468621 @default.
- W2884156795 cites W2762913643 @default.
- W2884156795 cites W4230920194 @default.
- W2884156795 doi "https://doi.org/10.1038/s41598-018-29295-9" @default.
- W2884156795 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6062561" @default.
- W2884156795 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30050078" @default.
- W2884156795 hasPublicationYear "2018" @default.
- W2884156795 type Work @default.
- W2884156795 sameAs 2884156795 @default.
- W2884156795 citedByCount "98" @default.
- W2884156795 countsByYear W28841567952019 @default.