Matches in SemOpenAlex for { <https://semopenalex.org/work/W2884349768> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2884349768 abstract "Background: Beta thalassemia syndromes are heterogeneous inherited disorders. They represent the commonest inherited hemoglobinopathies and constitute a com-mon public health problem. Patients suffering from these disorders ultimately devel-op complications including endocrinopathies secondary to transfusional iron over-load. Thyroid dysfunction is well documented in this context; however there is great disparity in its prevalence across the world. This study was designed to determine the frequency of thyroid dysfunction in multi-transfused (> 12 regular transfusions) beta thalassemia syndrome patients in District Peshawar Pakistan. Methodology: In this cross-sectional descriptive study, patients treated at Fatimid Foundation Peshawar were enrolled. One hundred and fifteen multi-transfused beta thalassemia syndrome patients >10 years of age were included. Data and blood samples were collected after taking written informed consent from patients/guardians. Venous blood (3ml) was collected in vacuette® (Griener, GmbH). After centrifugation, sera were separated and analyzed for T 4 , T 3 , TSH and ferritin levels by Chemiluminescence Immune Assay (CLIA) technique using Acculite Monobind Diagnostics on Lumax analyzer in IBMS. Results: Primary subclinical hypothyroidism was detected in 25 (21.7%) pa-tients. All patients were iron overloaded as indicated by very high serum ferri-tin levels (ranging from 1500-27042ng/ml). Conclusion: Hypothyroidism occurs mainly in subclinical state and is a fre-quent complication in iron overloaded beta thalassemia syndrome patients with risk of progression." @default.
- W2884349768 created "2018-08-03" @default.
- W2884349768 creator A5004017094 @default.
- W2884349768 date "2017-01-01" @default.
- W2884349768 modified "2023-09-25" @default.
- W2884349768 title "FREQUENCY OF HYPOTHYROIDISM IN MULTI-TRANSFUSED IRON OVERLOADED β-THALASSEMIA SYNDROME PATIENTS" @default.
- W2884349768 hasPublicationYear "2017" @default.
- W2884349768 type Work @default.
- W2884349768 sameAs 2884349768 @default.
- W2884349768 citedByCount "0" @default.
- W2884349768 crossrefType "journal-article" @default.
- W2884349768 hasAuthorship W2884349768A5004017094 @default.
- W2884349768 hasConcept C113280763 @default.
- W2884349768 hasConcept C126322002 @default.
- W2884349768 hasConcept C141071460 @default.
- W2884349768 hasConcept C151730666 @default.
- W2884349768 hasConcept C187212893 @default.
- W2884349768 hasConcept C2777218474 @default.
- W2884349768 hasConcept C2777799968 @default.
- W2884349768 hasConcept C2777940137 @default.
- W2884349768 hasConcept C2778319317 @default.
- W2884349768 hasConcept C2779343474 @default.
- W2884349768 hasConcept C2780622394 @default.
- W2884349768 hasConcept C71924100 @default.
- W2884349768 hasConcept C81182388 @default.
- W2884349768 hasConcept C86803240 @default.
- W2884349768 hasConceptScore W2884349768C113280763 @default.
- W2884349768 hasConceptScore W2884349768C126322002 @default.
- W2884349768 hasConceptScore W2884349768C141071460 @default.
- W2884349768 hasConceptScore W2884349768C151730666 @default.
- W2884349768 hasConceptScore W2884349768C187212893 @default.
- W2884349768 hasConceptScore W2884349768C2777218474 @default.
- W2884349768 hasConceptScore W2884349768C2777799968 @default.
- W2884349768 hasConceptScore W2884349768C2777940137 @default.
- W2884349768 hasConceptScore W2884349768C2778319317 @default.
- W2884349768 hasConceptScore W2884349768C2779343474 @default.
- W2884349768 hasConceptScore W2884349768C2780622394 @default.
- W2884349768 hasConceptScore W2884349768C71924100 @default.
- W2884349768 hasConceptScore W2884349768C81182388 @default.
- W2884349768 hasConceptScore W2884349768C86803240 @default.
- W2884349768 hasIssue "2" @default.
- W2884349768 hasLocation W28843497681 @default.
- W2884349768 hasOpenAccess W2884349768 @default.
- W2884349768 hasPrimaryLocation W28843497681 @default.
- W2884349768 hasRelatedWork W2032072018 @default.
- W2884349768 hasRelatedWork W2116587690 @default.
- W2884349768 hasRelatedWork W2183830422 @default.
- W2884349768 hasRelatedWork W2257266138 @default.
- W2884349768 hasRelatedWork W2554700248 @default.
- W2884349768 hasRelatedWork W2570697187 @default.
- W2884349768 hasRelatedWork W2573755812 @default.
- W2884349768 hasRelatedWork W2583747254 @default.
- W2884349768 hasRelatedWork W2594130036 @default.
- W2884349768 hasRelatedWork W2737694025 @default.
- W2884349768 hasRelatedWork W2784307629 @default.
- W2884349768 hasRelatedWork W2797434855 @default.
- W2884349768 hasRelatedWork W2904015046 @default.
- W2884349768 hasRelatedWork W2914086600 @default.
- W2884349768 hasRelatedWork W2945197066 @default.
- W2884349768 hasRelatedWork W3007890345 @default.
- W2884349768 hasRelatedWork W3106457978 @default.
- W2884349768 hasRelatedWork W3186405440 @default.
- W2884349768 hasRelatedWork W2294970327 @default.
- W2884349768 hasRelatedWork W3096305117 @default.
- W2884349768 hasVolume "1" @default.
- W2884349768 isParatext "false" @default.
- W2884349768 isRetracted "false" @default.
- W2884349768 magId "2884349768" @default.
- W2884349768 workType "article" @default.