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- W2884405141 abstract "Policy changes would mainly affect women, as safety recommendations have been issued about the use of the drug in women of childbearing age living with HIV. Esther Nakkazi reports from Kampala. Dolutegravir for HIV: a lesson in pregnancy safety researchPreliminary results prompted WHO, the European Medicines Agency, and the US Food and Drug Administration to issue warnings on May 18 about the use of dolutegravir, a first-line antiretroviral drug, by women at the time of conception. In an unplanned preliminary analysis of an ongoing 4-year observational study in Botswana, 0·9% (4/426) of babies whose mothers became pregnant while taking dolutegravir had a neural tube defect compared with 0·1% (14/11 173) of babies whose mothers took other HIV medicines. Full-Text PDF" @default.
- W2884405141 created "2018-08-03" @default.
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- W2884405141 date "2018-07-01" @default.
- W2884405141 modified "2023-09-26" @default.
- W2884405141 title "Changes to dolutegravir policy in several African countries" @default.
- W2884405141 doi "https://doi.org/10.1016/s0140-6736(18)31641-6" @default.
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