Matches in SemOpenAlex for { <https://semopenalex.org/work/W2884450897> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2884450897 endingPage "476" @default.
- W2884450897 startingPage "459" @default.
- W2884450897 abstract "With over 1.5 billion people, East Asians are the most populous race in the world. Health status in this population is an important global issue. In the contemporary trials of antithrombotic treatment, East Asian patients have a lower risk for atherothrombotic diseases (especially, Coronary Artery Disease [CAD]) and a higher risk for bleeding (especially, gastrointestinal bleeding and hemorrhagic stroke). Despite these observations, antithrombotic treatment strategies in East Asian patients are mainly based on the American or European guidelines that are derived from randomized, controlled trials including mostly Caucasians. Despite a low response to clopidogrel, East Asian patients with CAD show a similar or even a lower rate of ischemic event occurrence and higher bleeding risk compared with Caucasian patients. The latter is referred to as the East Asian Paradox, suggesting a dissimilar therapeutic window for antiplatelet therapy than Caucasians. In addition, different net clinical benefits have been observed between the races with potent P2Y12 inhibitors that may be related to racial differences in pharmacokinetic and pharmacodynamic profiles. Furthermore, there is emerging concern regarding differences between East Asian vs. Western patients in pharmacodynamic and clinical efficacies of anticoagulant agents. We now summarize experimental and clinical evidence of the efficacy and safety of antithrombotic agents in the East Asian population. We suggest the concept of race-tailored antithrombotic treatment in CAD patients and/or in patients undergoing percutaneous coronary intervention." @default.
- W2884450897 created "2018-08-03" @default.
- W2884450897 creator A5011626347 @default.
- W2884450897 creator A5012918602 @default.
- W2884450897 creator A5020893309 @default.
- W2884450897 creator A5056448859 @default.
- W2884450897 creator A5057103601 @default.
- W2884450897 date "2018-07-10" @default.
- W2884450897 modified "2023-10-02" @default.
- W2884450897 title "Should Antithrombotic Treatment Strategies in East Asians Differ from Caucasians?" @default.
- W2884450897 doi "https://doi.org/10.2174/1570161116666180117103238" @default.
- W2884450897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29345591" @default.
- W2884450897 hasPublicationYear "2018" @default.
- W2884450897 type Work @default.
- W2884450897 sameAs 2884450897 @default.
- W2884450897 citedByCount "29" @default.
- W2884450897 countsByYear W28844508972018 @default.
- W2884450897 countsByYear W28844508972019 @default.
- W2884450897 countsByYear W28844508972020 @default.
- W2884450897 countsByYear W28844508972021 @default.
- W2884450897 countsByYear W28844508972022 @default.
- W2884450897 countsByYear W28844508972023 @default.
- W2884450897 crossrefType "journal-article" @default.
- W2884450897 hasAuthorship W2884450897A5011626347 @default.
- W2884450897 hasAuthorship W2884450897A5012918602 @default.
- W2884450897 hasAuthorship W2884450897A5020893309 @default.
- W2884450897 hasAuthorship W2884450897A5056448859 @default.
- W2884450897 hasAuthorship W2884450897A5057103601 @default.
- W2884450897 hasConcept C126322002 @default.
- W2884450897 hasConcept C127413603 @default.
- W2884450897 hasConcept C168563851 @default.
- W2884450897 hasConcept C17744445 @default.
- W2884450897 hasConcept C177713679 @default.
- W2884450897 hasConcept C191935318 @default.
- W2884450897 hasConcept C199539241 @default.
- W2884450897 hasConcept C2777015399 @default.
- W2884450897 hasConcept C2777849778 @default.
- W2884450897 hasConcept C2778213512 @default.
- W2884450897 hasConcept C2780400711 @default.
- W2884450897 hasConcept C2780645631 @default.
- W2884450897 hasConcept C2908647359 @default.
- W2884450897 hasConcept C500558357 @default.
- W2884450897 hasConcept C535046627 @default.
- W2884450897 hasConcept C71924100 @default.
- W2884450897 hasConcept C76775654 @default.
- W2884450897 hasConcept C78519656 @default.
- W2884450897 hasConcept C99454951 @default.
- W2884450897 hasConceptScore W2884450897C126322002 @default.
- W2884450897 hasConceptScore W2884450897C127413603 @default.
- W2884450897 hasConceptScore W2884450897C168563851 @default.
- W2884450897 hasConceptScore W2884450897C17744445 @default.
- W2884450897 hasConceptScore W2884450897C177713679 @default.
- W2884450897 hasConceptScore W2884450897C191935318 @default.
- W2884450897 hasConceptScore W2884450897C199539241 @default.
- W2884450897 hasConceptScore W2884450897C2777015399 @default.
- W2884450897 hasConceptScore W2884450897C2777849778 @default.
- W2884450897 hasConceptScore W2884450897C2778213512 @default.
- W2884450897 hasConceptScore W2884450897C2780400711 @default.
- W2884450897 hasConceptScore W2884450897C2780645631 @default.
- W2884450897 hasConceptScore W2884450897C2908647359 @default.
- W2884450897 hasConceptScore W2884450897C500558357 @default.
- W2884450897 hasConceptScore W2884450897C535046627 @default.
- W2884450897 hasConceptScore W2884450897C71924100 @default.
- W2884450897 hasConceptScore W2884450897C76775654 @default.
- W2884450897 hasConceptScore W2884450897C78519656 @default.
- W2884450897 hasConceptScore W2884450897C99454951 @default.
- W2884450897 hasIssue "5" @default.
- W2884450897 hasLocation W28844508971 @default.
- W2884450897 hasLocation W28844508972 @default.
- W2884450897 hasOpenAccess W2884450897 @default.
- W2884450897 hasPrimaryLocation W28844508971 @default.
- W2884450897 hasRelatedWork W1973213952 @default.
- W2884450897 hasRelatedWork W1983829728 @default.
- W2884450897 hasRelatedWork W2236042039 @default.
- W2884450897 hasRelatedWork W2900348376 @default.
- W2884450897 hasRelatedWork W2981439523 @default.
- W2884450897 hasRelatedWork W2981847246 @default.
- W2884450897 hasRelatedWork W3141478988 @default.
- W2884450897 hasRelatedWork W1968744067 @default.
- W2884450897 hasRelatedWork W2527719101 @default.
- W2884450897 hasRelatedWork W2655856674 @default.
- W2884450897 hasVolume "16" @default.
- W2884450897 isParatext "false" @default.
- W2884450897 isRetracted "false" @default.
- W2884450897 magId "2884450897" @default.
- W2884450897 workType "article" @default.