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• W2884725400 abstract "Bacterial contamination and subsequent infections are a major threat to human health. An early detection in the food chain, clinics or the environment, is key to limit this threat. We present a new concept to develop low-cost hand-held devices for the ultra-sensitive and specific detection of bacteria in a one-step process of 2–8 h, directly from complex raw samples. This approach is based on a novel microfluidic magnetic fluidized bed. It reaches a 4 CFU (colony forming unit) sensitivity with high quantification accuracy in a large dynamic range of 100–107CFU/mL. The versatility of the approach was demonstrated with the detection of different bacteria strains, among which Salmonella Typhimurium and E. coli O157:H15. Additionally, the method is sensitive to infectious bacteria only, a criterion requested by main applications and currently requiring additional culture steps of one to several days." @default.
• W2884725400 created "2018-08-03" @default.
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• W2884725400 date "2018-01-01" @default.
• W2884725400 modified "2023-09-30" @default.
• W2884725400 title "A microfluidic fluidized bed to capture, amplify and detect bacteria from raw samples" @default.
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• W2884725400 doi "https://doi.org/10.1016/bs.mcb.2018.07.001" @default.
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