Matches in SemOpenAlex for { <https://semopenalex.org/work/W2884865453> ?p ?o ?g. }
- W2884865453 endingPage "2008" @default.
- W2884865453 startingPage "1997" @default.
- W2884865453 abstract "Insights into genetic loci which are under selection and their functional roles contribute to increased understanding of the patterns of phenotypic variation we observe today. The availability of whole-genome sequence data, for humans and other species, provides opportunities to investigate adaptation and evolution at unprecedented resolution. Many analytical methods have been developed to interrogate these large data sets and characterize signatures of selection in the genome. We review here recently developed methods and consider the impact of increased computing power and data availability on the detection of selection signatures. Consideration of demography, recombination and other confounding factors is important, and use of a range of methods in combination is a powerful route to resolving different forms of selection in genome sequence data. Overall, a substantial improvement in methods for application to whole-genome sequencing is evident, although further work is required to develop robust and computationally efficient approaches which may increase reproducibility across studies." @default.
- W2884865453 created "2018-08-03" @default.
- W2884865453 creator A5002940859 @default.
- W2884865453 creator A5030043929 @default.
- W2884865453 creator A5047697470 @default.
- W2884865453 creator A5063395028 @default.
- W2884865453 creator A5079069117 @default.
- W2884865453 date "2018-07-24" @default.
- W2884865453 modified "2023-09-30" @default.
- W2884865453 title "Sequencing era methods for identifying signatures of selection in the genome" @default.
- W2884865453 cites W1514574038 @default.
- W2884865453 cites W1582217180 @default.
- W2884865453 cites W1627352199 @default.
- W2884865453 cites W1908810753 @default.
- W2884865453 cites W1915191149 @default.
- W2884865453 cites W1964558095 @default.
- W2884865453 cites W1965170911 @default.
- W2884865453 cites W1968114652 @default.
- W2884865453 cites W1969898169 @default.
- W2884865453 cites W1976977842 @default.
- W2884865453 cites W1987882116 @default.
- W2884865453 cites W1989923963 @default.
- W2884865453 cites W2006617902 @default.
- W2884865453 cites W2016145816 @default.
- W2884865453 cites W2021509301 @default.
- W2884865453 cites W2025253353 @default.
- W2884865453 cites W2029983700 @default.
- W2884865453 cites W2032311106 @default.
- W2884865453 cites W2039895473 @default.
- W2884865453 cites W2040164651 @default.
- W2884865453 cites W2041825325 @default.
- W2884865453 cites W2053495832 @default.
- W2884865453 cites W2055543630 @default.
- W2884865453 cites W2058902296 @default.
- W2884865453 cites W2059201551 @default.
- W2884865453 cites W2064947972 @default.
- W2884865453 cites W2078622638 @default.
- W2884865453 cites W2091705028 @default.
- W2884865453 cites W2095340238 @default.
- W2884865453 cites W2096653176 @default.
- W2884865453 cites W2096739767 @default.
- W2884865453 cites W2105000786 @default.
- W2884865453 cites W2106100115 @default.
- W2884865453 cites W2106397195 @default.
- W2884865453 cites W2107390588 @default.
- W2884865453 cites W2109195195 @default.
- W2884865453 cites W2109687083 @default.
- W2884865453 cites W2110375571 @default.
- W2884865453 cites W2111699978 @default.
- W2884865453 cites W2115264273 @default.
- W2884865453 cites W2116360795 @default.
- W2884865453 cites W2116668053 @default.
- W2884865453 cites W2118078855 @default.
- W2884865453 cites W2119110311 @default.
- W2884865453 cites W2120748058 @default.
- W2884865453 cites W2123707618 @default.
- W2884865453 cites W2127864194 @default.
- W2884865453 cites W2130116386 @default.
- W2884865453 cites W2131888512 @default.
- W2884865453 cites W2140449543 @default.
- W2884865453 cites W2140784970 @default.
- W2884865453 cites W2143846841 @default.
- W2884865453 cites W2144658220 @default.
- W2884865453 cites W2145913466 @default.
- W2884865453 cites W2146624139 @default.
- W2884865453 cites W2148927912 @default.
- W2884865453 cites W2150645251 @default.
- W2884865453 cites W2151061572 @default.
- W2884865453 cites W2151409320 @default.
- W2884865453 cites W2152799443 @default.
- W2884865453 cites W2156487727 @default.
- W2884865453 cites W2156866331 @default.
- W2884865453 cites W2156918287 @default.
- W2884865453 cites W2157011755 @default.
- W2884865453 cites W2157149092 @default.
- W2884865453 cites W2158057251 @default.
- W2884865453 cites W2162157671 @default.
- W2884865453 cites W2163600007 @default.
- W2884865453 cites W2171656008 @default.
- W2884865453 cites W2203551296 @default.
- W2884865453 cites W2268963144 @default.
- W2884865453 cites W2291016016 @default.
- W2884865453 cites W2324938927 @default.
- W2884865453 cites W2332641356 @default.
- W2884865453 cites W2346180222 @default.
- W2884865453 cites W2508218419 @default.
- W2884865453 cites W2514919142 @default.
- W2884865453 cites W2529098614 @default.
- W2884865453 cites W2531014594 @default.
- W2884865453 cites W2621721891 @default.
- W2884865453 cites W2624585284 @default.
- W2884865453 cites W2737244277 @default.
- W2884865453 cites W2755613176 @default.
- W2884865453 cites W2765704149 @default.
- W2884865453 cites W2950732129 @default.
- W2884865453 cites W2951062006 @default.
- W2884865453 cites W2951189783 @default.
- W2884865453 cites W2952902252 @default.