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- W2884869611 abstract "Light-induced stimulation of neurons via photoactive surfaces offers rich opportunities for the development of therapeutic methods and high-resolution retinal prosthetic devices. Quantum dots serve as an attractive building block for such surfaces, as they can be easily functionalized to match the biocompatibility and charge transport requirements of cell stimulation. Although indium-based colloidal quantum dots with type-I band alignment have attracted significant attention as a nontoxic alternative to cadmium-based ones, little attention has been paid to their photovoltaic potential as type-II heterostructures. Herein, we demonstrate type-II indium phosphide/zinc oxide core/shell quantum dots that are incorporated into a photoelectrode structure for neural photostimulation. This induces a hyperpolarizing bioelectrical current that triggers the firing of a single neural cell at 4 μW mm–2, 26-fold lower than the ocular safety limit for continuous exposure to visible light. These findings show that nanomaterials can induce a biocompatible and effective biological junction and can introduce a route in the use of quantum dots in photoelectrode architectures for artificial retinal prostheses." @default.
- W2884869611 created "2018-08-03" @default.
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- W2884869611 date "2018-07-18" @default.
- W2884869611 modified "2023-10-17" @default.
- W2884869611 title "Effective Neural Photostimulation Using Indium-Based Type-II Quantum Dots" @default.
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- W2884869611 doi "https://doi.org/10.1021/acsnano.8b02976" @default.
- W2884869611 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6117749" @default.
- W2884869611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30020770" @default.
- W2884869611 hasPublicationYear "2018" @default.
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