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- W2884927110 abstract "ABSTRACT Characterizing the genetic variation underlying phenotypic traits is a central objective in biological research. This research has been hampered in the past by the limited genomic resources available for most non-model species. However, recent advances in sequencing technology and related genotyping methods are rapidly changing this. Here we report the use of genome-wide SNP data from the ecologically and commercially important marine fish species Chrysophrys auratus (snapper) to 1) construct the first linkage map for this species, 2) scan for growth QTLs, and 3) search for candidate genes in the surrounding QTL regions. The newly constructed linkage map contained ~11K SNP markers and is the densest map to date in the fish family Sparidae. Comparisons with available genome scaffolds indicated that overall marker placement was strongly correlated between the scaffolds and linkage map (R = 0.7), but at fine scales (< 5 cM) there were some precision limitations. Of the 24 linkage groups, which reflect the 24 chromosomes of this species, three were found to contain QTLs with genome-wide significance for growth-related traits. A scan for 13 known candidate growth genes located the genes for growth hormone, parvalbumin, and myogenin within 13.2, 2.6, and 5.0 cM of these genome-wide significant QTLs, respectively. The linkage map and QTLs found in this study will advance the investigation of genome structure and selective breeding in snapper." @default.
- W2884927110 created "2018-08-03" @default.
- W2884927110 creator A5013271022 @default.
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- W2884927110 date "2018-07-24" @default.
- W2884927110 modified "2023-09-25" @default.
- W2884927110 title "High-density linkage map and QTLs for growth in snapper (Chrysophrys auratus)" @default.
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- W2884927110 doi "https://doi.org/10.1101/376012" @default.
- W2884927110 hasPublicationYear "2018" @default.
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