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• W2884978857 abstract "To assess the prevalence, antecedents, and consequences of unawareness of memory impairment in dementia.Persons (n = 1,862) from a geographically defined community without dementia at enrollment subsequently underwent clinical classification (248 with dementia, 611 with mild cognitive impairment, 1,003 with no cognitive impairment), memory testing, and self-appraisal of memory. Memory performance was regressed on self-appraised memory, and the residuals served as an index of memory awareness. After clinical classification, participants completed brief cognitive testing at 3-year intervals for up to 15 years.When unawareness was defined as a score at or below thresholds ranging from the 15th to 25th percentiles, it was more common in dementia (67%-83%) and mild cognitive impairment (15%-33%) than in no cognitive impairment (2%-6%; all p < .001). A continuous measure of awareness (M = 0.00, SD = 0.61) was reduced by 0.37-unit in mild cognitive impairment (SE = 0.04, p < .001) and 1.04-unit in dementia (SE = 0.06), p < .001) compared with those without cognitive impairment, and these associations were weaker in Black persons than White persons (estimate for dementia by race = 0.37, SE = 0.12, p = .003; estimate for mild cognitive impairment by race = 0.30, SE = 0.08, p < .001). Higher premorbid neuroticism was associated with better memory awareness in dementia. Higher memory awareness was not related to mortality in mild cognitive impairment or dementia but had a marginal association with slower cognitive decline in mild cognitive impairment.Unawareness of memory impairment is a common manifestation of dementia, particularly in White persons, but is not strongly related to adverse disease outcomes. (PsycINFO Database Record (c) 2018 APA, all rights reserved)." @default.
• W2884978857 created "2018-08-03" @default.
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• W2884978857 date "2018-11-01" @default.
• W2884978857 modified "2023-10-16" @default.
• W2884978857 title "Antecedents and consequences of unawareness of memory impairment in dementia." @default.
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• W2884978857 doi "https://doi.org/10.1037/neu0000437" @default.
• W2884978857 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6234063" @default.
• W2884978857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30047756" @default.
• W2884978857 hasPublicationYear "2018" @default.
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