Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885019134> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2885019134 abstract "Our phylogenetic theory of pathology (algorrhythm of a disease development) is based on 1) a theory of biological functions and biological reactions in vivo; 2) regulation of biological functions, reactions, and metabolic processes at three phylogenetically different levels: а) autocrine (cell level); b) paracrine (in paracrine-regulated cell communities) and c) total organism level; 3) conceptions on formation of physiological and aphysiological processes («civilization» diseases) at various stages of phylogenesis. Universal pathogenesis of essential arterial hypertension and insulin resistance syndrome is based on functional discrepancy between phylogenetically early regulatory mechanisms at the level of paracrine cell communities and phylogenetically late regulation at the organism level. Pathogenic factors of this discrepancy are impaired biological functions of homeostasis, trophology, endoecology and adaptation. An increase in the content of unesterified fatty acids in the intercellular medium results from activation of lipolysis in paracrine community cells which cannot inhibit phylogenetically late insulin, but not in insulin-dependent adipocytes. The formation of pathogenesis of each metabolic pandemia occurs dynamically at different stages of phylogenesis." @default.
- W2885019134 created "2018-08-03" @default.
- W2885019134 creator A5006751676 @default.
- W2885019134 creator A5064840931 @default.
- W2885019134 date "2014-01-01" @default.
- W2885019134 modified "2023-09-25" @default.
- W2885019134 title "Phylogentic theory of pathology. Common phylogenetic features in the pathogenesis of essential arterial hyperntesion and insulin resistance syndrome" @default.
- W2885019134 doi "https://doi.org/10.26442/2075-082x_11.3.53-60" @default.
- W2885019134 hasPublicationYear "2014" @default.
- W2885019134 type Work @default.
- W2885019134 sameAs 2885019134 @default.
- W2885019134 citedByCount "0" @default.
- W2885019134 crossrefType "journal-article" @default.
- W2885019134 hasAuthorship W2885019134A5006751676 @default.
- W2885019134 hasAuthorship W2885019134A5064840931 @default.
- W2885019134 hasConcept C104317684 @default.
- W2885019134 hasConcept C126322002 @default.
- W2885019134 hasConcept C142724271 @default.
- W2885019134 hasConcept C193252679 @default.
- W2885019134 hasConcept C2777391703 @default.
- W2885019134 hasConcept C2779306644 @default.
- W2885019134 hasConcept C2780942790 @default.
- W2885019134 hasConcept C54355233 @default.
- W2885019134 hasConcept C60644358 @default.
- W2885019134 hasConcept C70721500 @default.
- W2885019134 hasConcept C71924100 @default.
- W2885019134 hasConcept C86803240 @default.
- W2885019134 hasConceptScore W2885019134C104317684 @default.
- W2885019134 hasConceptScore W2885019134C126322002 @default.
- W2885019134 hasConceptScore W2885019134C142724271 @default.
- W2885019134 hasConceptScore W2885019134C193252679 @default.
- W2885019134 hasConceptScore W2885019134C2777391703 @default.
- W2885019134 hasConceptScore W2885019134C2779306644 @default.
- W2885019134 hasConceptScore W2885019134C2780942790 @default.
- W2885019134 hasConceptScore W2885019134C54355233 @default.
- W2885019134 hasConceptScore W2885019134C60644358 @default.
- W2885019134 hasConceptScore W2885019134C70721500 @default.
- W2885019134 hasConceptScore W2885019134C71924100 @default.
- W2885019134 hasConceptScore W2885019134C86803240 @default.
- W2885019134 hasIssue "3" @default.
- W2885019134 hasLocation W28850191341 @default.
- W2885019134 hasOpenAccess W2885019134 @default.
- W2885019134 hasPrimaryLocation W28850191341 @default.
- W2885019134 hasRelatedWork W1828691184 @default.
- W2885019134 hasRelatedWork W1993951481 @default.
- W2885019134 hasRelatedWork W2002128513 @default.
- W2885019134 hasRelatedWork W2097383755 @default.
- W2885019134 hasRelatedWork W2141682026 @default.
- W2885019134 hasRelatedWork W2352105112 @default.
- W2885019134 hasRelatedWork W2376926255 @default.
- W2885019134 hasRelatedWork W2897718214 @default.
- W2885019134 hasRelatedWork W3127473566 @default.
- W2885019134 hasRelatedWork W2092874662 @default.
- W2885019134 hasVolume "11" @default.
- W2885019134 isParatext "false" @default.
- W2885019134 isRetracted "false" @default.
- W2885019134 magId "2885019134" @default.
- W2885019134 workType "article" @default.