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- W2885087161 abstract "Abstract Domestic animals play a key role in human survival and the development of civilization. However, the genetic resources of domestic animals are facing an alarming rate of erosion due to socioeconomic changes, economic globalization and financial constraints. In this study, through genome-wide SNP analysis, we estimated the heterozygosity, inbreeding coefficient, effective population size, and runs of homozygosity to identify the breeds facing the risk of extinction for sheep and cattle across the world. In particular, we quantified the contribution of 97 sheep breeds and 53 cattle breeds to genomic diversity (within-breed, between-breed and total) and prioritized the breeds for conservation. Additionally, we compared the average values of genomic diversity between breeds from regions (or countries) in different economic categories (underdeveloped, developing and developed), and found that breeds in developed regions exhibit significantly higher levels of total genomic diversity than those in underdeveloped and developing regions. Altogether, our results suggested that conservation priority should be given to breeds in developed regions to secure the future genomic diversity hotspots of domestic animal resources." @default.
- W2885087161 created "2018-08-22" @default.
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- W2885087161 date "2018-08-03" @default.
- W2885087161 modified "2023-09-26" @default.
- W2885087161 title "Global genomic diversity and conservation priorities for domestic animals are associated with the economies of their regions of origin" @default.
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- W2885087161 doi "https://doi.org/10.1038/s41598-018-30061-0" @default.
- W2885087161 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6076285" @default.
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