Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885100818> ?p ?o ?g. }
- W2885100818 abstract "Adhesion G protein-coupled receptors (aGPCRs) constitute the second largest GPCR subfamily. GPR56/ADGRG1 is a member of the ADGRG subgroup of aGPCRs. Although GPR56 is best known for its pivotal role in the cerebral cortical development, it is also important for tumor progression. Numerous studies have revealed that GPR56 is expressed in various cancer types with a role in cancer cell adhesion, migration and metastasis. In a recent study, we found that the immobilized GPR56-specific CG4 antibody enhanced IL-6 production and migration ability of melanoma cells. In this review, we will summarize the current understanding of GPR56 function and discuss the activation and signaling mechanisms of GPR56 in melanoma cells." @default.
- W2885100818 created "2018-08-22" @default.
- W2885100818 creator A5040236748 @default.
- W2885100818 creator A5059582877 @default.
- W2885100818 date "2018-08-08" @default.
- W2885100818 modified "2023-10-14" @default.
- W2885100818 title "The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell" @default.
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- W2885100818 doi "https://doi.org/10.3389/fonc.2018.00304" @default.
- W2885100818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6092491" @default.
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