FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885137992> ?p ?o ?g. }

• W2885137992 endingPage "73" @default.
• W2885137992 startingPage "67" @default.
• W2885137992 abstract "Cisplatin (CP) and doxorubicin (DX) can cause testicular injury by inducing oxidative/nitrosative stress, inflammation, and apoptosis, Naringenin (NG) has antioxidant, antinitrative, anti-inflammatory, and anti-apoptotic effects. This study investigated the potential ability of NG to block gonadotoxicity induced CP and DX in male rats. The rats received one injection of either CP (10 mg/kg, i.p.) or DX (15 mg/kg, i.p.), and treated with NG (50 mg/kg/day, p.o.) for 10 days beginning 6 days prior to CP and DX administration. NG significantly prevented the decreases of serum testosterone and inhibin B in rats received CP and DX. Additionally, NG significantly decreased the elevated testicular malondialdehyde, tumor necrosis factor-α/interleukin-10 ratio, and caspase-3 in CP- and DX-treated rats. NG also significantly raised the decreased testicular Bcl-2/Bax ratio, and total antioxidant status in CP- and DX-challenged rats. In addition, NG significantly increased P-glycoprotein level in testes of rats received CP and DX. Moreover, NG significantly decreased the testicular histopathological injury, and immunohistochemical expression of inducible nitric oxide synthase induced by CP and DX in rat testes. It was concluded that NG impeded gonadotoxicity of CP and DX in male rats by mitigating oxidative stress, nitrosative stress, inflammation, and apoptosis." @default.
• W2885137992 created "2018-08-22" @default.
• W2885137992 creator A5005899834 @default.
• W2885137992 creator A5020274532 @default.
• W2885137992 creator A5078884236 @default.
• W2885137992 date "2018-10-18" @default.
• W2885137992 modified "2023-10-01" @default.
• W2885137992 title "Naringenin palliates cisplatin and doxorubicin gonadal toxicity in male rats" @default.
• W2885137992 cites W1161717916 @default.
• W2885137992 cites W1532063289 @default.
• W2885137992 cites W1941929294 @default.
• W2885137992 cites W1977369444 @default.
• W2885137992 cites W2085141969 @default.
• W2885137992 cites W2094051883 @default.
• W2885137992 cites W2260810887 @default.
• W2885137992 cites W2290705662 @default.
• W2885137992 cites W2325179580 @default.
• W2885137992 cites W2461469936 @default.
• W2885137992 cites W2465650527 @default.
• W2885137992 cites W2474242420 @default.
• W2885137992 cites W2519200923 @default.
• W2885137992 cites W2579172774 @default.
• W2885137992 cites W2608599088 @default.
• W2885137992 cites W2611032038 @default.
• W2885137992 cites W2612484435 @default.
• W2885137992 cites W2613864865 @default.
• W2885137992 cites W2622640307 @default.
• W2885137992 cites W2734747373 @default.
• W2885137992 cites W2745675145 @default.
• W2885137992 cites W2761101077 @default.
• W2885137992 cites W2767263655 @default.
• W2885137992 cites W2771039248 @default.
• W2885137992 cites W2793637672 @default.
• W2885137992 cites W2794354813 @default.
• W2885137992 doi "https://doi.org/10.1080/15376516.2018.1512180" @default.
• W2885137992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30106323" @default.
• W2885137992 hasPublicationYear "2018" @default.
• W2885137992 type Work @default.
• W2885137992 sameAs 2885137992 @default.
• W2885137992 citedByCount "23" @default.
• W2885137992 countsByYear W28851379922019 @default.
• W2885137992 countsByYear W28851379922020 @default.
• W2885137992 countsByYear W28851379922021 @default.
• W2885137992 countsByYear W28851379922022 @default.
• W2885137992 countsByYear W28851379922023 @default.
• W2885137992 crossrefType "journal-article" @default.
• W2885137992 hasAuthorship W2885137992A5005899834 @default.
• W2885137992 hasAuthorship W2885137992A5020274532 @default.
• W2885137992 hasAuthorship W2885137992A5078884236 @default.
• W2885137992 hasConcept C126322002 @default.
• W2885137992 hasConcept C134018914 @default.
• W2885137992 hasConcept C185592680 @default.
• W2885137992 hasConcept C190283241 @default.
• W2885137992 hasConcept C2776151105 @default.
• W2885137992 hasConcept C2776694085 @default.
• W2885137992 hasConcept C2776848411 @default.
• W2885137992 hasConcept C2776914184 @default.
• W2885137992 hasConcept C2777622882 @default.
• W2885137992 hasConcept C2778004101 @default.
• W2885137992 hasConcept C2778401633 @default.
• W2885137992 hasConcept C2779054382 @default.
• W2885137992 hasConcept C2781303535 @default.
• W2885137992 hasConcept C29730261 @default.
• W2885137992 hasConcept C519581460 @default.
• W2885137992 hasConcept C55493867 @default.
• W2885137992 hasConcept C71924100 @default.
• W2885137992 hasConcept C98274493 @default.
• W2885137992 hasConceptScore W2885137992C126322002 @default.
• W2885137992 hasConceptScore W2885137992C134018914 @default.
• W2885137992 hasConceptScore W2885137992C185592680 @default.
• W2885137992 hasConceptScore W2885137992C190283241 @default.
• W2885137992 hasConceptScore W2885137992C2776151105 @default.
• W2885137992 hasConceptScore W2885137992C2776694085 @default.
• W2885137992 hasConceptScore W2885137992C2776848411 @default.
• W2885137992 hasConceptScore W2885137992C2776914184 @default.
• W2885137992 hasConceptScore W2885137992C2777622882 @default.
• W2885137992 hasConceptScore W2885137992C2778004101 @default.
• W2885137992 hasConceptScore W2885137992C2778401633 @default.
• W2885137992 hasConceptScore W2885137992C2779054382 @default.
• W2885137992 hasConceptScore W2885137992C2781303535 @default.
• W2885137992 hasConceptScore W2885137992C29730261 @default.
• W2885137992 hasConceptScore W2885137992C519581460 @default.
• W2885137992 hasConceptScore W2885137992C55493867 @default.
• W2885137992 hasConceptScore W2885137992C71924100 @default.
• W2885137992 hasConceptScore W2885137992C98274493 @default.
• W2885137992 hasIssue "1" @default.
• W2885137992 hasLocation W28851379921 @default.
• W2885137992 hasLocation W28851379922 @default.
• W2885137992 hasOpenAccess W2885137992 @default.
• W2885137992 hasPrimaryLocation W28851379921 @default.
• W2885137992 hasRelatedWork W1869058931 @default.
• W2885137992 hasRelatedWork W1987293786 @default.
• W2885137992 hasRelatedWork W2008087125 @default.
• W2885137992 hasRelatedWork W2089295326 @default.
• W2885137992 hasRelatedWork W2093911704 @default.
• W2885137992 hasRelatedWork W2098776639 @default.
• W2885137992 hasRelatedWork W2151132253 @default.
• W2885137992 hasRelatedWork W2525070109 @default.

• next