FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885186968> ?p ?o ?g. }

• W2885186968 abstract "Previous studies on linkage disequilibrium have investigated second order linkage disequilibrium in animal and plant populations. The objective of this paper was to investigate the genome-wide levels of third order linkage disequilibrium in a composite line founded by admixture of four Iberian pig strains. A model for the generation of third order linkage disequilibrium by population admixture is proposed. A computer Expectation-Maximization algorithm is developed and applied to the estimation of third order linkage disequilibrium at inter- and intra-chromosomal level using 26,347 SNPs typed in 306 sows. The relationship of third order linkage disequilibrium with physical distance was investigated over 35 million triplets in SSC12. Basic and normalized estimates of inter and intra-chromosomal third order linkage disequilibrium are reported.Genome-wide analyses revealed that third order linkage disequilibrium is rather common among linked loci in this Iberian pig line. It is shown that population admixture of multiple populations may explain the observed levels of third order linkage disequilibrium although it could be generated by genetic drift. Third order linkage disequilibrium decreases rapidly up to 4 Mb and then declines slowly. The short distances between consecutive markers explain the maintenance of the observed third order linkage disequilibria levels when using a model incorporating the break-up of disequilibrium by recombination. Genome-wide testing also revealed that only 3.6% of the normalized estimates were different from 1, - 1, 0, or from a not well-defined situation in which there is only one possible value for the third order linkage disequilibrium parameter, given allele frequencies and pairwise linkage disequilibria parameters.Third order linkage disequilibrium is common among linked markers in the analyzed pig line and may have been generated by population admixture of multiple populations or by genetic drift. As with second order linkage disequilibrium, the absolute value of the third order linkage disequilibrium decreases with physical distance. Normalization of third order linkage disequilibrium should be avoided for closely linked bi-allelic loci." @default.
• W2885186968 created "2018-08-22" @default.
• W2885186968 creator A5003300845 @default.
• W2885186968 creator A5017637220 @default.
• W2885186968 creator A5056645298 @default.
• W2885186968 creator A5061387861 @default.
• W2885186968 creator A5074763555 @default.
• W2885186968 date "2018-08-17" @default.
• W2885186968 modified "2023-10-18" @default.
• W2885186968 title "Extent of third-order linkage disequilibrium in a composite line of Iberian pigs" @default.
• W2885186968 cites W1486272424 @default.
• W2885186968 cites W1558993377 @default.
• W2885186968 cites W1887682009 @default.
• W2885186968 cites W1891283710 @default.
• W2885186968 cites W1928998639 @default.
• W2885186968 cites W1933519219 @default.
• W2885186968 cites W1935277267 @default.
• W2885186968 cites W1964910627 @default.
• W2885186968 cites W2003859026 @default.
• W2885186968 cites W2004917170 @default.
• W2885186968 cites W2012175544 @default.
• W2885186968 cites W2022776726 @default.
• W2885186968 cites W2042103448 @default.
• W2885186968 cites W2049816819 @default.
• W2885186968 cites W2070881032 @default.
• W2885186968 cites W2091239497 @default.
• W2885186968 cites W2094189284 @default.
• W2885186968 cites W2101021009 @default.
• W2885186968 cites W2117908893 @default.
• W2885186968 cites W2139030037 @default.
• W2885186968 cites W2141001738 @default.
• W2885186968 cites W2155670634 @default.
• W2885186968 cites W2159487337 @default.
• W2885186968 cites W2160717298 @default.
• W2885186968 cites W2326742012 @default.
• W2885186968 doi "https://doi.org/10.1186/s12863-018-0661-4" @default.
• W2885186968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6098602" @default.
• W2885186968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30119622" @default.
• W2885186968 hasPublicationYear "2018" @default.
• W2885186968 type Work @default.
• W2885186968 sameAs 2885186968 @default.
• W2885186968 citedByCount "1" @default.
• W2885186968 countsByYear W28851869682021 @default.
• W2885186968 crossrefType "journal-article" @default.
• W2885186968 hasAuthorship W2885186968A5003300845 @default.
• W2885186968 hasAuthorship W2885186968A5017637220 @default.
• W2885186968 hasAuthorship W2885186968A5056645298 @default.
• W2885186968 hasAuthorship W2885186968A5061387861 @default.
• W2885186968 hasAuthorship W2885186968A5074763555 @default.
• W2885186968 hasBestOaLocation W28851869681 @default.
• W2885186968 hasConcept C104317684 @default.
• W2885186968 hasConcept C118487528 @default.
• W2885186968 hasConcept C135763542 @default.
• W2885186968 hasConcept C144024400 @default.
• W2885186968 hasConcept C149923435 @default.
• W2885186968 hasConcept C153209595 @default.
• W2885186968 hasConcept C186413461 @default.
• W2885186968 hasConcept C2778146401 @default.
• W2885186968 hasConcept C2908647359 @default.
• W2885186968 hasConcept C31266012 @default.
• W2885186968 hasConcept C35605836 @default.
• W2885186968 hasConcept C54355233 @default.
• W2885186968 hasConcept C71924100 @default.
• W2885186968 hasConcept C78458016 @default.
• W2885186968 hasConcept C86803240 @default.
• W2885186968 hasConceptScore W2885186968C104317684 @default.
• W2885186968 hasConceptScore W2885186968C118487528 @default.
• W2885186968 hasConceptScore W2885186968C135763542 @default.
• W2885186968 hasConceptScore W2885186968C144024400 @default.
• W2885186968 hasConceptScore W2885186968C149923435 @default.
• W2885186968 hasConceptScore W2885186968C153209595 @default.
• W2885186968 hasConceptScore W2885186968C186413461 @default.
• W2885186968 hasConceptScore W2885186968C2778146401 @default.
• W2885186968 hasConceptScore W2885186968C2908647359 @default.
• W2885186968 hasConceptScore W2885186968C31266012 @default.
• W2885186968 hasConceptScore W2885186968C35605836 @default.
• W2885186968 hasConceptScore W2885186968C54355233 @default.
• W2885186968 hasConceptScore W2885186968C71924100 @default.
• W2885186968 hasConceptScore W2885186968C78458016 @default.
• W2885186968 hasConceptScore W2885186968C86803240 @default.
• W2885186968 hasFunder F4320320300 @default.
• W2885186968 hasIssue "1" @default.
• W2885186968 hasLocation W28851869681 @default.
• W2885186968 hasLocation W28851869682 @default.
• W2885186968 hasLocation W28851869683 @default.
• W2885186968 hasLocation W28851869684 @default.
• W2885186968 hasOpenAccess W2885186968 @default.
• W2885186968 hasPrimaryLocation W28851869681 @default.
• W2885186968 hasRelatedWork W1565120531 @default.
• W2885186968 hasRelatedWork W1911749773 @default.
• W2885186968 hasRelatedWork W1916312508 @default.
• W2885186968 hasRelatedWork W1975676017 @default.
• W2885186968 hasRelatedWork W2036613411 @default.
• W2885186968 hasRelatedWork W2139678309 @default.
• W2885186968 hasRelatedWork W2148559943 @default.
• W2885186968 hasRelatedWork W233618048 @default.
• W2885186968 hasRelatedWork W4240990629 @default.
• W2885186968 hasRelatedWork W4254143844 @default.
• W2885186968 hasVolume "19" @default.
• W2885186968 isParatext "false" @default.

• next