FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885194819> ?p ?o ?g. }

• W2885194819 endingPage "228" @default.
• W2885194819 startingPage "218" @default.
• W2885194819 abstract "Reasons for the well-described disparity in outcomes between African American (AA) and non-Hispanic white (NHW) women with invasive breast cancer are unclear, making it difficult to identify solutions. This study examined the effects of demographics, biomarkers, tumor characteristics, cancer stage, morphology, and treatment variables on overall and cancer-free survival in these patient populations.We retrospectively reviewed data for 6231 patients diagnosed with invasive breast cancer throughout an integrated health system from January 2006 through March 2015. Included for analysis were 5023 NHW and 413 AA women. All category and continuous variables in the study were described in the two groups using appropriate statistics. Kaplan-Meier method of survival with log-rank test was used to compare the two racial groups (NHW and AA). Cox proportional hazards regression was used to find hazard ratios for the predictors of survival and recurrence-free survival probability. Propensity probability match method (1:1) was used to match 319 NSW women to 319 similar AA women. Matching was done using all significant predictors, including demographic variables.Compared to NHW women, AA women presented with invasive breast cancer at a younger age (P<0.001) and had a higher proportion of stage IV cancers (P<0.001), which were more often infiltrating ductal carcinoma (P<0.003) and poorly differentiated (P<0.001). Within 10-year follow-up, AA women had shorter overall and recurrence-free survival (log-rank P<0.001), were 1.4 times more likely to die (P=0.009), and were twice as likely to have recurrence (P<0.001) than NHW women. In the matched groups, overall survival was similar for AA and NHW (log-rank P=0.0793); however, recurrence-free survival was higher in NHW than in AA women (P=0.047).When presenting characteristics of AA and NHW women with invasive breast cancer are matched, disparity in overall mortality and rate of recurrence appears to be reduced or perhaps eliminated, suggesting invasive breast cancers in AA and NHW women respond similarly to treatment. Further study is needed to explore the true effect of biological factors; however, rectifying delivery of and access to care might be expected to mitigate, in large part, the racial disparity currently seen in breast cancer outcomes." @default.
• W2885194819 created "2018-08-22" @default.
• W2885194819 creator A5003183865 @default.
• W2885194819 creator A5039961300 @default.
• W2885194819 creator A5047199449 @default.
• W2885194819 creator A5067903216 @default.
• W2885194819 creator A5068931556 @default.
• W2885194819 date "2018-07-30" @default.
• W2885194819 modified "2023-10-12" @default.
• W2885194819 title "Racial Disparity Among Women Diagnosed With Invasive Breast Cancer in a Large Integrated Health System" @default.
• W2885194819 cites W1513217966 @default.
• W2885194819 cites W1830454849 @default.
• W2885194819 cites W1986179950 @default.
• W2885194819 cites W2016763041 @default.
• W2885194819 cites W2038723222 @default.
• W2885194819 cites W2052387052 @default.
• W2885194819 cites W2067428007 @default.
• W2885194819 cites W2079924572 @default.
• W2885194819 cites W2110571385 @default.
• W2885194819 cites W2164961968 @default.
• W2885194819 cites W2166846975 @default.
• W2885194819 cites W2330410810 @default.
• W2885194819 cites W2527743943 @default.
• W2885194819 cites W2542861534 @default.
• W2885194819 cites W2567001274 @default.
• W2885194819 cites W2592729719 @default.
• W2885194819 cites W2600129852 @default.
• W2885194819 cites W2605515535 @default.
• W2885194819 cites W2713575692 @default.
• W2885194819 cites W2765942869 @default.
• W2885194819 doi "https://doi.org/10.17294/2330-0698.1621" @default.
• W2885194819 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6664325" @default.
• W2885194819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31414006" @default.
• W2885194819 hasPublicationYear "2018" @default.
• W2885194819 type Work @default.
• W2885194819 sameAs 2885194819 @default.
• W2885194819 citedByCount "3" @default.
• W2885194819 countsByYear W28851948192020 @default.
• W2885194819 countsByYear W28851948192021 @default.
• W2885194819 crossrefType "journal-article" @default.
• W2885194819 hasAuthorship W2885194819A5003183865 @default.
• W2885194819 hasAuthorship W2885194819A5039961300 @default.
• W2885194819 hasAuthorship W2885194819A5047199449 @default.
• W2885194819 hasAuthorship W2885194819A5067903216 @default.
• W2885194819 hasAuthorship W2885194819A5068931556 @default.
• W2885194819 hasBestOaLocation W28851948191 @default.
• W2885194819 hasConcept C10515644 @default.
• W2885194819 hasConcept C121608353 @default.
• W2885194819 hasConcept C126322002 @default.
• W2885194819 hasConcept C143998085 @default.
• W2885194819 hasConcept C144024400 @default.
• W2885194819 hasConcept C146357865 @default.
• W2885194819 hasConcept C149923435 @default.
• W2885194819 hasConcept C151730666 @default.
• W2885194819 hasConcept C17923572 @default.
• W2885194819 hasConcept C207103383 @default.
• W2885194819 hasConcept C2780084366 @default.
• W2885194819 hasConcept C29456083 @default.
• W2885194819 hasConcept C44249647 @default.
• W2885194819 hasConcept C50382708 @default.
• W2885194819 hasConcept C530470458 @default.
• W2885194819 hasConcept C66339696 @default.
• W2885194819 hasConcept C71924100 @default.
• W2885194819 hasConcept C86803240 @default.
• W2885194819 hasConceptScore W2885194819C10515644 @default.
• W2885194819 hasConceptScore W2885194819C121608353 @default.
• W2885194819 hasConceptScore W2885194819C126322002 @default.
• W2885194819 hasConceptScore W2885194819C143998085 @default.
• W2885194819 hasConceptScore W2885194819C144024400 @default.
• W2885194819 hasConceptScore W2885194819C146357865 @default.
• W2885194819 hasConceptScore W2885194819C149923435 @default.
• W2885194819 hasConceptScore W2885194819C151730666 @default.
• W2885194819 hasConceptScore W2885194819C17923572 @default.
• W2885194819 hasConceptScore W2885194819C207103383 @default.
• W2885194819 hasConceptScore W2885194819C2780084366 @default.
• W2885194819 hasConceptScore W2885194819C29456083 @default.
• W2885194819 hasConceptScore W2885194819C44249647 @default.
• W2885194819 hasConceptScore W2885194819C50382708 @default.
• W2885194819 hasConceptScore W2885194819C530470458 @default.
• W2885194819 hasConceptScore W2885194819C66339696 @default.
• W2885194819 hasConceptScore W2885194819C71924100 @default.
• W2885194819 hasConceptScore W2885194819C86803240 @default.
• W2885194819 hasIssue "3" @default.
• W2885194819 hasLocation W28851948191 @default.
• W2885194819 hasLocation W28851948192 @default.
• W2885194819 hasLocation W28851948193 @default.
• W2885194819 hasLocation W28851948194 @default.
• W2885194819 hasOpenAccess W2885194819 @default.
• W2885194819 hasPrimaryLocation W28851948191 @default.
• W2885194819 hasRelatedWork W2055804777 @default.
• W2885194819 hasRelatedWork W2093548677 @default.
• W2885194819 hasRelatedWork W2558534037 @default.
• W2885194819 hasRelatedWork W2760851598 @default.
• W2885194819 hasRelatedWork W3096243511 @default.
• W2885194819 hasRelatedWork W3136369250 @default.
• W2885194819 hasRelatedWork W3191941344 @default.
• W2885194819 hasRelatedWork W3198560290 @default.
• W2885194819 hasRelatedWork W4238506989 @default.

• next