Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885200749> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2885200749 abstract "Fluid overload in chronic kidney disease (CKD) is generally controlled by diuretics, with potentially harmful effects on renal function. The efficacy of tolvaptan, a vasopressin V2-receptor antagonist and aquaretic, has not been evaluated for fluid control in CKD with reduced renal function.Each patient from a group of 24 CKD patients on tolvaptan 15 mg/d plus conventional diuretics (T group) was matched by age and sex with a patient from a group of 24 CKD patients on conventional nonaquaretic diuretics alone not associated to tolvaptan other than tolvaptan (C group). Changes in renal function were compared between the groups for 1 year.There were no significant differences in blood pressure, hemoglobin levels, cardiac function, urine specific gravity, and urinary sodium concentration between the 2 groups at the beginning of the follow-up period and 1 year after. The estimated glomerular filtration rate (eGFR) by the formula developed by Japanese Society of Nephrology (in mL/min/1.73 m2) decreased: C group (from 28.3±13.6 to 23.0±12.3, p=0.09), T group (from 22.7±12.4 to 19.4±12.2, p=0.18), but both did not reach significance. A 50% reduction in eGFR was observed in 4 patients in the C group and 1 in the T group (p<0.05). A subgroup analysis performed on the patients with stage 3-4 CKD demonstrated a significant reduction in eGFR in the C group (n=17, p=0.04), but not in T group (n=17, p=0.07).These results suggest that tolvaptan may have less effects on CKD progression among stage 3-4 CKD patients who are on conventional diuretics." @default.
- W2885200749 created "2018-08-22" @default.
- W2885200749 creator A5024728176 @default.
- W2885200749 creator A5029940262 @default.
- W2885200749 creator A5037218495 @default.
- W2885200749 creator A5067789661 @default.
- W2885200749 creator A5088334303 @default.
- W2885200749 date "2018-08-01" @default.
- W2885200749 modified "2023-09-25" @default.
- W2885200749 title "Effects of tolvaptan on renal function in chronic kidney disease patients with volume overload" @default.
- W2885200749 cites W1947627127 @default.
- W2885200749 cites W1967917175 @default.
- W2885200749 cites W1988397924 @default.
- W2885200749 cites W2029110123 @default.
- W2885200749 cites W2042277624 @default.
- W2885200749 cites W2064249981 @default.
- W2885200749 cites W2071655353 @default.
- W2885200749 cites W2152189242 @default.
- W2885200749 cites W2276596278 @default.
- W2885200749 cites W2346597670 @default.
- W2885200749 cites W2586466743 @default.
- W2885200749 cites W2594452743 @default.
- W2885200749 cites W2604990911 @default.
- W2885200749 cites W2734738746 @default.
- W2885200749 cites W2754038054 @default.
- W2885200749 cites W2765637142 @default.
- W2885200749 cites W2765795120 @default.
- W2885200749 cites W2766192961 @default.
- W2885200749 cites W2767604355 @default.
- W2885200749 doi "https://doi.org/10.2147/ijnrd.s167694" @default.
- W2885200749 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6103308" @default.
- W2885200749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30147354" @default.
- W2885200749 hasPublicationYear "2018" @default.
- W2885200749 type Work @default.
- W2885200749 sameAs 2885200749 @default.
- W2885200749 citedByCount "2" @default.
- W2885200749 countsByYear W28852007492020 @default.
- W2885200749 countsByYear W28852007492022 @default.
- W2885200749 crossrefType "journal-article" @default.
- W2885200749 hasAuthorship W2885200749A5024728176 @default.
- W2885200749 hasAuthorship W2885200749A5029940262 @default.
- W2885200749 hasAuthorship W2885200749A5037218495 @default.
- W2885200749 hasAuthorship W2885200749A5067789661 @default.
- W2885200749 hasAuthorship W2885200749A5088334303 @default.
- W2885200749 hasBestOaLocation W28852007491 @default.
- W2885200749 hasConcept C126322002 @default.
- W2885200749 hasConcept C126894567 @default.
- W2885200749 hasConcept C134018914 @default.
- W2885200749 hasConcept C159641895 @default.
- W2885200749 hasConcept C170493617 @default.
- W2885200749 hasConcept C2776370428 @default.
- W2885200749 hasConcept C2776885963 @default.
- W2885200749 hasConcept C2778534349 @default.
- W2885200749 hasConcept C2778653478 @default.
- W2885200749 hasConcept C2779881253 @default.
- W2885200749 hasConcept C2780615674 @default.
- W2885200749 hasConcept C54847362 @default.
- W2885200749 hasConcept C71924100 @default.
- W2885200749 hasConcept C90924648 @default.
- W2885200749 hasConceptScore W2885200749C126322002 @default.
- W2885200749 hasConceptScore W2885200749C126894567 @default.
- W2885200749 hasConceptScore W2885200749C134018914 @default.
- W2885200749 hasConceptScore W2885200749C159641895 @default.
- W2885200749 hasConceptScore W2885200749C170493617 @default.
- W2885200749 hasConceptScore W2885200749C2776370428 @default.
- W2885200749 hasConceptScore W2885200749C2776885963 @default.
- W2885200749 hasConceptScore W2885200749C2778534349 @default.
- W2885200749 hasConceptScore W2885200749C2778653478 @default.
- W2885200749 hasConceptScore W2885200749C2779881253 @default.
- W2885200749 hasConceptScore W2885200749C2780615674 @default.
- W2885200749 hasConceptScore W2885200749C54847362 @default.
- W2885200749 hasConceptScore W2885200749C71924100 @default.
- W2885200749 hasConceptScore W2885200749C90924648 @default.
- W2885200749 hasLocation W28852007491 @default.
- W2885200749 hasLocation W28852007492 @default.
- W2885200749 hasLocation W28852007493 @default.
- W2885200749 hasLocation W28852007494 @default.
- W2885200749 hasLocation W28852007495 @default.
- W2885200749 hasOpenAccess W2885200749 @default.
- W2885200749 hasPrimaryLocation W28852007491 @default.
- W2885200749 hasRelatedWork W1964596246 @default.
- W2885200749 hasRelatedWork W1993936129 @default.
- W2885200749 hasRelatedWork W2003587549 @default.
- W2885200749 hasRelatedWork W2057585929 @default.
- W2885200749 hasRelatedWork W2066805988 @default.
- W2885200749 hasRelatedWork W2067237682 @default.
- W2885200749 hasRelatedWork W2071155830 @default.
- W2885200749 hasRelatedWork W2127850904 @default.
- W2885200749 hasRelatedWork W2146713571 @default.
- W2885200749 hasRelatedWork W2181117567 @default.
- W2885200749 isParatext "false" @default.
- W2885200749 isRetracted "false" @default.
- W2885200749 magId "2885200749" @default.
- W2885200749 workType "article" @default.