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- W2885203774 abstract "Background: Genetic factor plays an important role in the pathogenesis of moyamoya disease (MMD). Previous studies concentrated on the familial patients. In this study, we focus on the family members of sporadic MMD patients, and aim to gain a clearer understanding of the role that genetic factor plays in MMD. Methods: The immediate family members of MMD patients were initially screened by Transcranial Doppler Sonography (TCD) and the positive cases were verified by Magnetic Resonance Angiography (MRA). A total of 285 immediate family members of 245 sporadic MMD patients (2011.07-2013.03) were screened. Results: 33 cases were confirmed positive at 11.6% detection rate. 21 cases (from 20 index MMD patients) was validated by MRA. As a result, the proportion of familial MMD patients in our hospital increased from 7% (38/527) to 15% (79/527) in this period. For the main segments of the circle of Willis, which include the anterior cerebral arteries (ACA), middle cerebral arteries (MCA) and posterior cerebral a..." @default.
- W2885203774 created "2018-08-22" @default.
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- W2885203774 date "2014-02-01" @default.
- W2885203774 modified "2023-09-26" @default.
- W2885203774 title "Abstract T P165: Prospective Screening of Family Members With Moyamoya Disease Patients" @default.
- W2885203774 hasPublicationYear "2014" @default.
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