Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885224668> ?p ?o ?g. }
- W2885224668 endingPage "1749" @default.
- W2885224668 startingPage "1740" @default.
- W2885224668 abstract "The use of multiple-pulse amperometry (MPA) for the determination of narrow therapeutic index (NTI) drugs using batch injection analysis (BIA) with carbon screen-printed electrodes (SPE) is proposed, seeking to develop a practical and low-cost analysis kit for application in routine quality control of these drugs. The electrochemical behaviors of aminophylline, carbamazepine, clindamycin, colchicine, minoxidil, prazosin, procainamide, theophylline, warfarin and verapamil were evaluated in different electrolytes, but just one, the 0.1 mol L−1 phosphate buffer, pH 7.0, was chosen for determination of all the analytes. The amperometric detection was optimized as a function of the best oxidation potential for carbon SPE for each analyte, which was in a range from 0.7 to 1.1 V. The injection conditions were determined as a function of the velocity and the volume injected by the BIA system, which were 92.5 μL s−1 and 100 μL, respectively. Under these conditions, a good repeatability (RSD<3 %), high analytical frequency (>215 determinations per hour), large linear ranges and low LOD (<0.42 μmol L−1) for all the NTI drugs were obtained. Furthermore, the proposed method provided an easy qualitative analysis of the investigated analytes using MPA detection. The addition-recovery studies in pharmaceutical samples containing NTI drugs and the comparison with official methods showed that the proposed analysis Kit is a very fast, simple and efficient alternative for quantification of these analytes." @default.
- W2885224668 created "2018-08-22" @default.
- W2885224668 creator A5057416043 @default.
- W2885224668 creator A5090577101 @default.
- W2885224668 date "2018-04-06" @default.
- W2885224668 modified "2023-09-23" @default.
- W2885224668 title "Fast and Simple Electrochemical Analysis Kit for Quality Control of Narrow Therapeutic Index Drugs" @default.
- W2885224668 cites W1275572581 @default.
- W2885224668 cites W1557409852 @default.
- W2885224668 cites W1803189785 @default.
- W2885224668 cites W1880787720 @default.
- W2885224668 cites W1936548672 @default.
- W2885224668 cites W1964518134 @default.
- W2885224668 cites W1964821467 @default.
- W2885224668 cites W1966174426 @default.
- W2885224668 cites W1968028676 @default.
- W2885224668 cites W1968127261 @default.
- W2885224668 cites W1968543655 @default.
- W2885224668 cites W1970939924 @default.
- W2885224668 cites W1970960017 @default.
- W2885224668 cites W1975916672 @default.
- W2885224668 cites W1980319235 @default.
- W2885224668 cites W1981363666 @default.
- W2885224668 cites W1985730840 @default.
- W2885224668 cites W1985740657 @default.
- W2885224668 cites W1989788528 @default.
- W2885224668 cites W1990607928 @default.
- W2885224668 cites W1998867491 @default.
- W2885224668 cites W1999072636 @default.
- W2885224668 cites W2000105394 @default.
- W2885224668 cites W2000937610 @default.
- W2885224668 cites W2004963159 @default.
- W2885224668 cites W2005455905 @default.
- W2885224668 cites W2006669774 @default.
- W2885224668 cites W2007921058 @default.
- W2885224668 cites W2017916801 @default.
- W2885224668 cites W2021123817 @default.
- W2885224668 cites W2025846948 @default.
- W2885224668 cites W2027455923 @default.
- W2885224668 cites W2035194169 @default.
- W2885224668 cites W2041616749 @default.
- W2885224668 cites W2041972618 @default.
- W2885224668 cites W2044129446 @default.
- W2885224668 cites W2044206509 @default.
- W2885224668 cites W2044220706 @default.
- W2885224668 cites W2045762870 @default.
- W2885224668 cites W2047621768 @default.
- W2885224668 cites W2048377739 @default.
- W2885224668 cites W2052684443 @default.
- W2885224668 cites W2055329848 @default.
- W2885224668 cites W2059659659 @default.
- W2885224668 cites W2061713955 @default.
- W2885224668 cites W2062473650 @default.
- W2885224668 cites W2063483580 @default.
- W2885224668 cites W2065333692 @default.
- W2885224668 cites W2066253206 @default.
- W2885224668 cites W2068480387 @default.
- W2885224668 cites W2070087473 @default.
- W2885224668 cites W2072607974 @default.
- W2885224668 cites W2074934169 @default.
- W2885224668 cites W2077456437 @default.
- W2885224668 cites W2077876069 @default.
- W2885224668 cites W2080709510 @default.
- W2885224668 cites W2082003630 @default.
- W2885224668 cites W2084238255 @default.
- W2885224668 cites W2091210705 @default.
- W2885224668 cites W2092879763 @default.
- W2885224668 cites W2099778602 @default.
- W2885224668 cites W2107351272 @default.
- W2885224668 cites W2131751284 @default.
- W2885224668 cites W2133370337 @default.
- W2885224668 cites W2134636279 @default.
- W2885224668 cites W2149159459 @default.
- W2885224668 cites W2155554699 @default.
- W2885224668 cites W2160805427 @default.
- W2885224668 cites W2238646054 @default.
- W2885224668 cites W2273582519 @default.
- W2885224668 cites W2276629069 @default.
- W2885224668 cites W2278361770 @default.
- W2885224668 cites W2282836503 @default.
- W2885224668 cites W2285669159 @default.
- W2885224668 cites W2292870090 @default.
- W2885224668 cites W2294391977 @default.
- W2885224668 cites W2294958889 @default.
- W2885224668 cites W2295117067 @default.
- W2885224668 cites W2312313603 @default.
- W2885224668 cites W2320273518 @default.
- W2885224668 cites W2326512780 @default.
- W2885224668 cites W2334769681 @default.
- W2885224668 cites W2339472502 @default.
- W2885224668 cites W2346428987 @default.
- W2885224668 cites W2470546276 @default.
- W2885224668 cites W2477242853 @default.
- W2885224668 cites W2507878624 @default.
- W2885224668 cites W2544485984 @default.
- W2885224668 cites W2559924605 @default.
- W2885224668 cites W2561279193 @default.
- W2885224668 cites W2564133304 @default.