Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885244228> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2885244228 abstract "The analysis of expression of the hTERT protein, the methylation status of the hTERT gene as the type of HPV infection, will contribute to deepen the role played by HPV infection in the expression and methylation of hTERT. The study included a group of one hundred fifty-five samples of women with squamous cell carcinomas of the uterine cervix in stage FIGO IIB-IIIB treated at the National Cancer Institute in Bogota, Colombia. The expression of the hTERT protein was detected by immunohistochemistry both at the nuclear level and at the cytoplasmic level. In 79.7% of the cases, the protein was expressed at the nuclear level and 78% at the cytoplasmic level. HPV16, the most frequent viral type found, was detected by means of a GP5+/GP6+ mediated PCR- RLB in 84.4% and in 82.2% of the cases that expressed hTERT at the nuclear level and at the cytoplasmic level, respectively; with respect to HPV species, both at the nuclear level and at the cytoplasmic level, the species most frequently found was the alpha 9 species (HPVs 16, 31, 35, 52.58) followed by alpha 7 (HPVs 18, 45.59) and alpha 6 (HPVs 56, 66). In the multiple correspondence analyzes, a close relationship was observed between the cytoplasmic expression as nuclear of hTERT and the alpha species 9. A distant relationship was also observed between the expression of the protein and methylation, as well as between the non-methylation and the alpha 7 family of HPV; likewise, a distant relationship was observed between the non-methylation of hTERT and the alpha 9 species. The analyzes carried out show a possible relationship between the expression of the hTERT protein and the alpha 9 HPV species. Citation Format: Pablo Moreno-Acosta, Monica Molano, Nicolas Morales, Alfredo Romero-Rojas, Oscar Gamboa, Jinneth Acosta, Raynner Alvarez, Nicolas Magne, Nubia Munoz. hTERT protein expression, hTERT methylation and HPV infection in uterine cervical cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4328." @default.
- W2885244228 created "2018-08-22" @default.
- W2885244228 creator A5000953051 @default.
- W2885244228 creator A5001628805 @default.
- W2885244228 creator A5005141145 @default.
- W2885244228 creator A5007876507 @default.
- W2885244228 creator A5013372032 @default.
- W2885244228 creator A5036026276 @default.
- W2885244228 creator A5039689469 @default.
- W2885244228 creator A5067554612 @default.
- W2885244228 creator A5075904496 @default.
- W2885244228 date "2018-07-01" @default.
- W2885244228 modified "2023-10-04" @default.
- W2885244228 title "Abstract 4328: hTERT protein expression, hTERT methylation and HPV infection in uterine cervical cancer" @default.
- W2885244228 doi "https://doi.org/10.1158/1538-7445.am2018-4328" @default.
- W2885244228 hasPublicationYear "2018" @default.
- W2885244228 type Work @default.
- W2885244228 sameAs 2885244228 @default.
- W2885244228 citedByCount "0" @default.
- W2885244228 crossrefType "proceedings-article" @default.
- W2885244228 hasAuthorship W2885244228A5000953051 @default.
- W2885244228 hasAuthorship W2885244228A5001628805 @default.
- W2885244228 hasAuthorship W2885244228A5005141145 @default.
- W2885244228 hasAuthorship W2885244228A5007876507 @default.
- W2885244228 hasAuthorship W2885244228A5013372032 @default.
- W2885244228 hasAuthorship W2885244228A5036026276 @default.
- W2885244228 hasAuthorship W2885244228A5039689469 @default.
- W2885244228 hasAuthorship W2885244228A5067554612 @default.
- W2885244228 hasAuthorship W2885244228A5075904496 @default.
- W2885244228 hasConcept C104317684 @default.
- W2885244228 hasConcept C121608353 @default.
- W2885244228 hasConcept C125593758 @default.
- W2885244228 hasConcept C150194340 @default.
- W2885244228 hasConcept C153911025 @default.
- W2885244228 hasConcept C159110408 @default.
- W2885244228 hasConcept C190062978 @default.
- W2885244228 hasConcept C190727270 @default.
- W2885244228 hasConcept C203014093 @default.
- W2885244228 hasConcept C204232928 @default.
- W2885244228 hasConcept C2775944032 @default.
- W2885244228 hasConcept C2778220009 @default.
- W2885244228 hasConcept C33288867 @default.
- W2885244228 hasConcept C49453240 @default.
- W2885244228 hasConcept C502942594 @default.
- W2885244228 hasConcept C54355233 @default.
- W2885244228 hasConcept C64943373 @default.
- W2885244228 hasConcept C71924100 @default.
- W2885244228 hasConcept C86803240 @default.
- W2885244228 hasConcept C94581717 @default.
- W2885244228 hasConceptScore W2885244228C104317684 @default.
- W2885244228 hasConceptScore W2885244228C121608353 @default.
- W2885244228 hasConceptScore W2885244228C125593758 @default.
- W2885244228 hasConceptScore W2885244228C150194340 @default.
- W2885244228 hasConceptScore W2885244228C153911025 @default.
- W2885244228 hasConceptScore W2885244228C159110408 @default.
- W2885244228 hasConceptScore W2885244228C190062978 @default.
- W2885244228 hasConceptScore W2885244228C190727270 @default.
- W2885244228 hasConceptScore W2885244228C203014093 @default.
- W2885244228 hasConceptScore W2885244228C204232928 @default.
- W2885244228 hasConceptScore W2885244228C2775944032 @default.
- W2885244228 hasConceptScore W2885244228C2778220009 @default.
- W2885244228 hasConceptScore W2885244228C33288867 @default.
- W2885244228 hasConceptScore W2885244228C49453240 @default.
- W2885244228 hasConceptScore W2885244228C502942594 @default.
- W2885244228 hasConceptScore W2885244228C54355233 @default.
- W2885244228 hasConceptScore W2885244228C64943373 @default.
- W2885244228 hasConceptScore W2885244228C71924100 @default.
- W2885244228 hasConceptScore W2885244228C86803240 @default.
- W2885244228 hasConceptScore W2885244228C94581717 @default.
- W2885244228 hasLocation W28852442281 @default.
- W2885244228 hasOpenAccess W2885244228 @default.
- W2885244228 hasPrimaryLocation W28852442281 @default.
- W2885244228 hasRelatedWork W1498739650 @default.
- W2885244228 hasRelatedWork W1981998601 @default.
- W2885244228 hasRelatedWork W2039360811 @default.
- W2885244228 hasRelatedWork W2162405641 @default.
- W2885244228 hasRelatedWork W2190893384 @default.
- W2885244228 hasRelatedWork W2373284446 @default.
- W2885244228 hasRelatedWork W2383278250 @default.
- W2885244228 hasRelatedWork W3136848747 @default.
- W2885244228 hasRelatedWork W4281609249 @default.
- W2885244228 hasRelatedWork W2760557785 @default.
- W2885244228 isParatext "false" @default.
- W2885244228 isRetracted "false" @default.
- W2885244228 magId "2885244228" @default.
- W2885244228 workType "article" @default.