Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885307522> ?p ?o ?g. }
- W2885307522 endingPage "e1006361" @default.
- W2885307522 startingPage "e1006361" @default.
- W2885307522 abstract "Single-cell RNA sequencing (scRNA-seq) technology allows researchers to profile the transcriptomes of thousands of cells simultaneously. Protocols that incorporate both designed and random barcodes have greatly increased the throughput of scRNA-seq, but give rise to a more complex data structure. There is a need for new tools that can handle the various barcoding strategies used by different protocols and exploit this information for quality assessment at the sample-level and provide effective visualization of these results in preparation for higher-level analyses. To this end, we developed scPipe, an R/Bioconductor package that integrates barcode demultiplexing, read alignment, UMI-aware gene-level quantification and quality control of raw sequencing data generated by multiple protocols that include CEL-seq, MARS-seq, Chromium 10X, Drop-seq and Smart-seq. scPipe produces a count matrix that is essential for downstream analysis along with an HTML report that summarises data quality. These results can be used as input for downstream analyses including normalization, visualization and statistical testing. scPipe performs this processing in a few simple R commands, promoting reproducible analysis of single-cell data that is compatible with the emerging suite of open-source scRNA-seq analysis tools available in R/Bioconductor and beyond. The scPipe R package is available for download from https://www.bioconductor.org/packages/scPipe." @default.
- W2885307522 created "2018-08-22" @default.
- W2885307522 creator A5000883053 @default.
- W2885307522 creator A5009825116 @default.
- W2885307522 creator A5015434839 @default.
- W2885307522 creator A5038651475 @default.
- W2885307522 creator A5054240555 @default.
- W2885307522 creator A5056109480 @default.
- W2885307522 creator A5056492561 @default.
- W2885307522 creator A5063944841 @default.
- W2885307522 creator A5078395814 @default.
- W2885307522 date "2018-08-10" @default.
- W2885307522 modified "2023-10-13" @default.
- W2885307522 title "scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data" @default.
- W2885307522 cites W1973094248 @default.
- W2885307522 cites W1984883254 @default.
- W2885307522 cites W2030017878 @default.
- W2885307522 cites W2102212449 @default.
- W2885307522 cites W2110905563 @default.
- W2885307522 cites W2130116522 @default.
- W2885307522 cites W2138207763 @default.
- W2885307522 cites W2150892663 @default.
- W2885307522 cites W2159325249 @default.
- W2885307522 cites W2169456326 @default.
- W2885307522 cites W2190545194 @default.
- W2885307522 cites W2342688693 @default.
- W2885307522 cites W2516455020 @default.
- W2885307522 cites W2519132385 @default.
- W2885307522 cites W2540833380 @default.
- W2885307522 cites W2591733518 @default.
- W2885307522 cites W2598326928 @default.
- W2885307522 cites W2783644856 @default.
- W2885307522 cites W2809616137 @default.
- W2885307522 cites W2949829455 @default.
- W2885307522 cites W2950541340 @default.
- W2885307522 cites W2951158909 @default.
- W2885307522 cites W2951337536 @default.
- W2885307522 cites W2951506174 @default.
- W2885307522 cites W2952109315 @default.
- W2885307522 cites W2953170162 @default.
- W2885307522 cites W585085135 @default.
- W2885307522 cites W839653734 @default.
- W2885307522 doi "https://doi.org/10.1371/journal.pcbi.1006361" @default.
- W2885307522 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6105007" @default.
- W2885307522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30096152" @default.
- W2885307522 hasPublicationYear "2018" @default.
- W2885307522 type Work @default.
- W2885307522 sameAs 2885307522 @default.
- W2885307522 citedByCount "91" @default.
- W2885307522 countsByYear W28853075222018 @default.
- W2885307522 countsByYear W28853075222019 @default.
- W2885307522 countsByYear W28853075222020 @default.
- W2885307522 countsByYear W28853075222021 @default.
- W2885307522 countsByYear W28853075222022 @default.
- W2885307522 countsByYear W28853075222023 @default.
- W2885307522 crossrefType "journal-article" @default.
- W2885307522 hasAuthorship W2885307522A5000883053 @default.
- W2885307522 hasAuthorship W2885307522A5009825116 @default.
- W2885307522 hasAuthorship W2885307522A5015434839 @default.
- W2885307522 hasAuthorship W2885307522A5038651475 @default.
- W2885307522 hasAuthorship W2885307522A5054240555 @default.
- W2885307522 hasAuthorship W2885307522A5056109480 @default.
- W2885307522 hasAuthorship W2885307522A5056492561 @default.
- W2885307522 hasAuthorship W2885307522A5063944841 @default.
- W2885307522 hasAuthorship W2885307522A5078395814 @default.
- W2885307522 hasBestOaLocation W28853075221 @default.
- W2885307522 hasConcept C104317684 @default.
- W2885307522 hasConcept C111919701 @default.
- W2885307522 hasConcept C124101348 @default.
- W2885307522 hasConcept C154945302 @default.
- W2885307522 hasConcept C166957645 @default.
- W2885307522 hasConcept C199360897 @default.
- W2885307522 hasConcept C2776841711 @default.
- W2885307522 hasConcept C2779694297 @default.
- W2885307522 hasConcept C34736171 @default.
- W2885307522 hasConcept C36464697 @default.
- W2885307522 hasConcept C41008148 @default.
- W2885307522 hasConcept C43521106 @default.
- W2885307522 hasConcept C55493867 @default.
- W2885307522 hasConcept C79581498 @default.
- W2885307522 hasConcept C86803240 @default.
- W2885307522 hasConcept C95457728 @default.
- W2885307522 hasConceptScore W2885307522C104317684 @default.
- W2885307522 hasConceptScore W2885307522C111919701 @default.
- W2885307522 hasConceptScore W2885307522C124101348 @default.
- W2885307522 hasConceptScore W2885307522C154945302 @default.
- W2885307522 hasConceptScore W2885307522C166957645 @default.
- W2885307522 hasConceptScore W2885307522C199360897 @default.
- W2885307522 hasConceptScore W2885307522C2776841711 @default.
- W2885307522 hasConceptScore W2885307522C2779694297 @default.
- W2885307522 hasConceptScore W2885307522C34736171 @default.
- W2885307522 hasConceptScore W2885307522C36464697 @default.
- W2885307522 hasConceptScore W2885307522C41008148 @default.
- W2885307522 hasConceptScore W2885307522C43521106 @default.
- W2885307522 hasConceptScore W2885307522C55493867 @default.
- W2885307522 hasConceptScore W2885307522C79581498 @default.
- W2885307522 hasConceptScore W2885307522C86803240 @default.
- W2885307522 hasConceptScore W2885307522C95457728 @default.