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• W2885319954 endingPage "624" @default.
• W2885319954 startingPage "611" @default.
• W2885319954 abstract "Introduction: HBV reactivation (HBVr) in patients undergoing immunosuppressive therapy is a well-known event. While there are clear directives on the management of current or resolved HBV infection in onco-hematological diseases, there are few data regarding patients with non-oncological diseases. Thus, the aim of the present review is to evaluate HBVr in patients with non-oncological diseases, and identify the management of these patients to prevent HBVr.Areas covered: Original papers, case reports and meta-analyses reporting data on HBVr of current or resolved infection in gastrointestinal, dermatological, rheumatologic and neurological diseases were evaluated.Expert commentary: In HBsAg-positive subjects, those with HBV-related hepatitis (both HBeAg-positive or negative) should be treated with a high genetic barrier nucleos(t)ide analog. The patients with HBV-infection (both HBeAg-positive and negative) an antiviral prophylaxis should be used, with lamivudine in those HBeAg-negative without signs of advanced liver disease, and with ETV, TDF or TAF in all the HBeAg-positive or in those HBeAg-negative with signs of advanced liver disease. In HBsAg-negative/anti-HBc positive subjects, when the risk of HBV reactivation is moderate (use of B-cell depleting agents), a prophylaxis-strategy may be considered; instead, in those with low risk of HBVr, a pre-emptive therapy strategy may be used." @default.
• W2885319954 created "2018-08-22" @default.
• W2885319954 creator A5000860411 @default.
• W2885319954 creator A5021807899 @default.
• W2885319954 creator A5038733459 @default.
• W2885319954 creator A5066445066 @default.
• W2885319954 creator A5076842883 @default.
• W2885319954 creator A5090068751 @default.
• W2885319954 date "2018-08-03" @default.
• W2885319954 modified "2023-10-16" @default.
• W2885319954 title "Management of HBV reactivation in non-oncological patients" @default.
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• W2885319954 doi "https://doi.org/10.1080/14787210.2018.1505501" @default.
• W2885319954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30058401" @default.

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