Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885361288> ?p ?o ?g. }
- W2885361288 endingPage "199" @default.
- W2885361288 startingPage "192" @default.
- W2885361288 abstract "To assess the impact of hepatitis B surface (HBsAg) seroclearance on survival outcomes in hepatitis B-related primary liver cancer.Information from patients with hepatitis B-related liver cancer admitted in our hospital from 2008-2017 was retrieved. Cases diagnosed with HBsAg (-) and HBcAb (+) liver cancer were included in the HBsAg seroclearance (SC) group. HBsAg (+) liver cancer patients strictly matched for liver cancer stage (AJCC staging system, 8th edition), Child-Pugh score, and first diagnosis/treatment method (surgery, ablation and TACE) were assigned to the HBsAg non-seroclearance (NSC) group. Then, clinical, pathological and survival data in both groups were assessed.The SC and NSC groups comprised of 72 and 216 patients, respectively. Patient age (P < 0.001) and platelet count (P = 0.001) in the SC group were significantly higher than those of the NSC group. SC group patients who underwent surgery had more intrahepatic cholangiocarcinoma (ICC) and combined HCC-CC (CHC) cases than the NSC group, but no significant differences in tumor cell differentiation and history of liver cirrhosis were found between the two groups. The numbers of interventional treatments were similar in both groups (4.57 vs 5.07, P > 0.05). Overall survival was lower in the SC group than the NSC group (P = 0.019), with 1-, 3-, and 5-year survival rates of 82.1% vs 85.1%, 43.2% vs 56.8%, and 27.0% vs 45.2%, respectively. Survival of patients with AJCC stage I disease in the SC group was lower than that of the NSC group (P = 0.029).Seroclearance in patients with hepatitis B-related primary liver cancer has protective effects with respect to tumorigenesis, cirrhosis, and portal hypertension but confers worse prognosis, which may be due to the frequent occurrence of highly malignant ICC and CHC." @default.
- W2885361288 created "2018-08-22" @default.
- W2885361288 creator A5000944793 @default.
- W2885361288 creator A5010688786 @default.
- W2885361288 creator A5032249239 @default.
- W2885361288 creator A5084192186 @default.
- W2885361288 creator A5088966589 @default.
- W2885361288 date "2018-08-16" @default.
- W2885361288 modified "2023-10-18" @default.
- W2885361288 title "Negative impact of hepatitis B surface seroclearance on prognosis of hepatitis B-related primary liver cancer" @default.
- W2885361288 cites W1846437462 @default.
- W2885361288 cites W1968503956 @default.
- W2885361288 cites W1994195219 @default.
- W2885361288 cites W2006657514 @default.
- W2885361288 cites W2009474584 @default.
- W2885361288 cites W2024267100 @default.
- W2885361288 cites W2033120556 @default.
- W2885361288 cites W2042681575 @default.
- W2885361288 cites W2075153264 @default.
- W2885361288 cites W2080195918 @default.
- W2885361288 cites W2080366818 @default.
- W2885361288 cites W2086342653 @default.
- W2885361288 cites W2090782873 @default.
- W2885361288 cites W2092596093 @default.
- W2885361288 cites W2108435608 @default.
- W2885361288 cites W2114785561 @default.
- W2885361288 cites W2130396153 @default.
- W2885361288 cites W2137652792 @default.
- W2885361288 cites W2148314869 @default.
- W2885361288 cites W2344715720 @default.
- W2885361288 cites W2409697102 @default.
- W2885361288 cites W2429224764 @default.
- W2885361288 cites W2549547375 @default.
- W2885361288 cites W2577513658 @default.
- W2885361288 cites W2770081722 @default.
- W2885361288 cites W2791548437 @default.
- W2885361288 cites W4211026375 @default.
- W2885361288 doi "https://doi.org/10.12998/wjcc.v6.i8.192" @default.
- W2885361288 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6107526" @default.
- W2885361288 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30148147" @default.
- W2885361288 hasPublicationYear "2018" @default.
- W2885361288 type Work @default.
- W2885361288 sameAs 2885361288 @default.
- W2885361288 citedByCount "1" @default.
- W2885361288 countsByYear W28853612882023 @default.
- W2885361288 crossrefType "journal-article" @default.
- W2885361288 hasAuthorship W2885361288A5000944793 @default.
- W2885361288 hasAuthorship W2885361288A5010688786 @default.
- W2885361288 hasAuthorship W2885361288A5032249239 @default.
- W2885361288 hasAuthorship W2885361288A5084192186 @default.
- W2885361288 hasAuthorship W2885361288A5088966589 @default.
- W2885361288 hasBestOaLocation W28853612881 @default.
- W2885361288 hasConcept C121608353 @default.
- W2885361288 hasConcept C126322002 @default.
- W2885361288 hasConcept C146357865 @default.
- W2885361288 hasConcept C151730666 @default.
- W2885361288 hasConcept C203014093 @default.
- W2885361288 hasConcept C2522874641 @default.
- W2885361288 hasConcept C2776029263 @default.
- W2885361288 hasConcept C2776231280 @default.
- W2885361288 hasConcept C2777214474 @default.
- W2885361288 hasConcept C2777382497 @default.
- W2885361288 hasConcept C2777410769 @default.
- W2885361288 hasConcept C2778019345 @default.
- W2885361288 hasConcept C2780593183 @default.
- W2885361288 hasConcept C71924100 @default.
- W2885361288 hasConcept C86803240 @default.
- W2885361288 hasConcept C90924648 @default.
- W2885361288 hasConceptScore W2885361288C121608353 @default.
- W2885361288 hasConceptScore W2885361288C126322002 @default.
- W2885361288 hasConceptScore W2885361288C146357865 @default.
- W2885361288 hasConceptScore W2885361288C151730666 @default.
- W2885361288 hasConceptScore W2885361288C203014093 @default.
- W2885361288 hasConceptScore W2885361288C2522874641 @default.
- W2885361288 hasConceptScore W2885361288C2776029263 @default.
- W2885361288 hasConceptScore W2885361288C2776231280 @default.
- W2885361288 hasConceptScore W2885361288C2777214474 @default.
- W2885361288 hasConceptScore W2885361288C2777382497 @default.
- W2885361288 hasConceptScore W2885361288C2777410769 @default.
- W2885361288 hasConceptScore W2885361288C2778019345 @default.
- W2885361288 hasConceptScore W2885361288C2780593183 @default.
- W2885361288 hasConceptScore W2885361288C71924100 @default.
- W2885361288 hasConceptScore W2885361288C86803240 @default.
- W2885361288 hasConceptScore W2885361288C90924648 @default.
- W2885361288 hasIssue "8" @default.
- W2885361288 hasLocation W28853612881 @default.
- W2885361288 hasLocation W28853612882 @default.
- W2885361288 hasLocation W28853612883 @default.
- W2885361288 hasOpenAccess W2885361288 @default.
- W2885361288 hasPrimaryLocation W28853612881 @default.
- W2885361288 hasRelatedWork W125090411 @default.
- W2885361288 hasRelatedWork W1993126248 @default.
- W2885361288 hasRelatedWork W2061799564 @default.
- W2885361288 hasRelatedWork W2080635925 @default.
- W2885361288 hasRelatedWork W2095133085 @default.
- W2885361288 hasRelatedWork W2325100393 @default.
- W2885361288 hasRelatedWork W2418826069 @default.
- W2885361288 hasRelatedWork W2464211120 @default.