Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885388829> ?p ?o ?g. }
- W2885388829 abstract "Abstract Live intracellular imaging is a valuable tool in modern diagnostics and pharmacology. Surface Enhanced Raman Spectroscopy (SERS) stands out as a non-destructive and multiplexed technique, but intracellular SERS imaging still suffers from interfering background from endogenous components. Here we show the assembly of small colloidal SERS probes with Raman signal in the cell-silent window of 1800–2900 cm −1 for biorthogonal intracellular SERS imaging of dopamine that was undistinguishable from the endogenous cell background. By linking colloidal silver nanoparticles with alkyne-dopamine adducts, clusters are formed by 2–6 nanoparticles spaced by tight interparticle gaps that exhibited high electric field enhancement and strong SERS signals of alkyne and dopamines. Due to the cell-silent signals of the alkyne, intracellular in-vitro Raman imaging shows that the dopamines on the internalized clusters remain distinguishable across the cytoplasm with good spatial resolution. Our method can be a general-purpose method for real-time imaging of biomolecules, such as proteins, peptides, DNA and drugs." @default.
- W2885388829 created "2018-08-22" @default.
- W2885388829 creator A5026510530 @default.
- W2885388829 creator A5029663159 @default.
- W2885388829 creator A5047189927 @default.
- W2885388829 creator A5049264937 @default.
- W2885388829 creator A5059089464 @default.
- W2885388829 creator A5060899621 @default.
- W2885388829 creator A5065268137 @default.
- W2885388829 creator A5075075610 @default.
- W2885388829 creator A5078963624 @default.
- W2885388829 creator A5079521716 @default.
- W2885388829 creator A5091322349 @default.
- W2885388829 date "2018-08-23" @default.
- W2885388829 modified "2023-09-27" @default.
- W2885388829 title "Live Intracellular Biorthogonal Imaging by Surface Enhanced Raman Spectroscopy using Alkyne-Silver Nanoparticles Clusters" @default.
- W2885388829 cites W1552820890 @default.
- W2885388829 cites W167281892 @default.
- W2885388829 cites W1972635232 @default.
- W2885388829 cites W1986076794 @default.
- W2885388829 cites W1995911703 @default.
- W2885388829 cites W2004575831 @default.
- W2885388829 cites W2008885546 @default.
- W2885388829 cites W2010014537 @default.
- W2885388829 cites W2013262011 @default.
- W2885388829 cites W2014144915 @default.
- W2885388829 cites W2020452657 @default.
- W2885388829 cites W2023861623 @default.
- W2885388829 cites W2024832835 @default.
- W2885388829 cites W2037912676 @default.
- W2885388829 cites W2038780437 @default.
- W2885388829 cites W2039524626 @default.
- W2885388829 cites W2039976599 @default.
- W2885388829 cites W2042747446 @default.
- W2885388829 cites W2043304167 @default.
- W2885388829 cites W2049963741 @default.
- W2885388829 cites W2055182244 @default.
- W2885388829 cites W2057685678 @default.
- W2885388829 cites W2067386938 @default.
- W2885388829 cites W2069742881 @default.
- W2885388829 cites W2075832148 @default.
- W2885388829 cites W2080637633 @default.
- W2885388829 cites W2085234762 @default.
- W2885388829 cites W2100593340 @default.
- W2885388829 cites W2145706118 @default.
- W2885388829 cites W2149487009 @default.
- W2885388829 cites W2152366705 @default.
- W2885388829 cites W2153852524 @default.
- W2885388829 cites W2161568165 @default.
- W2885388829 cites W2166806803 @default.
- W2885388829 cites W2172124640 @default.
- W2885388829 cites W2258519056 @default.
- W2885388829 cites W2319288524 @default.
- W2885388829 cites W2319876782 @default.
- W2885388829 cites W2322531587 @default.
- W2885388829 cites W2325005634 @default.
- W2885388829 cites W2337133817 @default.
- W2885388829 cites W2343071601 @default.
- W2885388829 cites W2402706228 @default.
- W2885388829 cites W2429279702 @default.
- W2885388829 cites W2465761634 @default.
- W2885388829 cites W2509285027 @default.
- W2885388829 cites W2517530801 @default.
- W2885388829 cites W2520129511 @default.
- W2885388829 cites W2544485086 @default.
- W2885388829 cites W2549132203 @default.
- W2885388829 cites W2566147354 @default.
- W2885388829 cites W2581428361 @default.
- W2885388829 cites W2585374782 @default.
- W2885388829 cites W2605479282 @default.
- W2885388829 cites W2624498804 @default.
- W2885388829 doi "https://doi.org/10.1038/s41598-018-31165-3" @default.
- W2885388829 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6107644" @default.
- W2885388829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30140073" @default.
- W2885388829 hasPublicationYear "2018" @default.
- W2885388829 type Work @default.
- W2885388829 sameAs 2885388829 @default.
- W2885388829 citedByCount "22" @default.
- W2885388829 countsByYear W28853888292019 @default.
- W2885388829 countsByYear W28853888292020 @default.
- W2885388829 countsByYear W28853888292021 @default.
- W2885388829 countsByYear W28853888292022 @default.
- W2885388829 countsByYear W28853888292023 @default.
- W2885388829 crossrefType "journal-article" @default.
- W2885388829 hasAuthorship W2885388829A5026510530 @default.
- W2885388829 hasAuthorship W2885388829A5029663159 @default.
- W2885388829 hasAuthorship W2885388829A5047189927 @default.
- W2885388829 hasAuthorship W2885388829A5049264937 @default.
- W2885388829 hasAuthorship W2885388829A5059089464 @default.
- W2885388829 hasAuthorship W2885388829A5060899621 @default.
- W2885388829 hasAuthorship W2885388829A5065268137 @default.
- W2885388829 hasAuthorship W2885388829A5075075610 @default.
- W2885388829 hasAuthorship W2885388829A5078963624 @default.
- W2885388829 hasAuthorship W2885388829A5079521716 @default.
- W2885388829 hasAuthorship W2885388829A5091322349 @default.
- W2885388829 hasBestOaLocation W28853888291 @default.
- W2885388829 hasConcept C120665830 @default.
- W2885388829 hasConcept C121332964 @default.
- W2885388829 hasConcept C12554922 @default.
- W2885388829 hasConcept C155672457 @default.