FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885398889> ?p ?o ?g. }

• W2885398889 abstract "518 Background: gallbladder cancer is the most common malignancy of the biliary tract. Treatment modalities and outcomes for this disease in Mexican population have been infrequently reported. Methods: we retrospectively reviewed medical records from 61 patients with histologically confirmed gallbladder cancer treated at Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán from January 2005 to December 2015.Clinical and pathological information was recorded. Survival was estimated by Kaplan Meir method and compared by Log rank test. Results: we found 68.9% women and 31.1% men, with a median age of 68 years (32-93). Clinical stage was advanced in 65.6% (n=40), regional in 23% (n=14), localized in 4.9% (n=3) and in situ in 6.6% (n=4). For patients with localized disease (n=21), which included in situ, localized and regional disease, a potentially curative surgery was attempted in 100% of patients, achieving a R0 resection in 47.6% (n=10) of cases. The morbidity rate was 33.3% (n=7). There were 5 surgical deaths. For advanced disease (n=40), the initial treatment was: 42.5% (n=17) palliative surgery, 25% (n=10) palliative care and for 30% (n=12) systemic chemotherapy, more frequently gemcitabine plus cisplatin (n=7). At progression seven patients received second-line chemotherapy. Median overall survival (OS) in the global cohort was 5.6 months (IC 95, 2.4-8.77). According to clinical stage survival at 5 years was 100% for in situ and 67% for localized disease. Median survival was 6.3 months (IC 95, 2.3-10-3) for regional disease and 4.2 months (IC 95, 1.1-6.4) for advanced disease. For patients with localized disease not achieving R0 resection (p=0.03) and perineural invasion (p=0.025) were associated with decreased survival. For patients with advanced disease poor performance status (p=0.004) and absence of chemotherapy (p=0.002) were adverse prognostic factors. Conclusions: global poor outcomes may be explained by metastatic disease at presentation. Even for patients with apparent localized disease, a potentially curative resection could be offered to only half of the patients." @default.
• W2885398889 created "2018-08-22" @default.
• W2885398889 creator A5011450963 @default.
• W2885398889 creator A5026965806 @default.
• W2885398889 creator A5042259513 @default.
• W2885398889 creator A5050447027 @default.
• W2885398889 creator A5054041848 @default.
• W2885398889 creator A5064112154 @default.
• W2885398889 creator A5081851183 @default.
• W2885398889 creator A5086478424 @default.
• W2885398889 date "2018-02-01" @default.
• W2885398889 modified "2023-09-27" @default.
• W2885398889 title "Oncological outcomes in a Mexican cohort of patients with gallbladder cancer." @default.
• W2885398889 doi "https://doi.org/10.1200/jco.2018.36.4_suppl.518" @default.
• W2885398889 hasPublicationYear "2018" @default.
• W2885398889 type Work @default.
• W2885398889 sameAs 2885398889 @default.
• W2885398889 citedByCount "0" @default.
• W2885398889 crossrefType "journal-article" @default.
• W2885398889 hasAuthorship W2885398889A5011450963 @default.
• W2885398889 hasAuthorship W2885398889A5026965806 @default.
• W2885398889 hasAuthorship W2885398889A5042259513 @default.
• W2885398889 hasAuthorship W2885398889A5050447027 @default.
• W2885398889 hasAuthorship W2885398889A5054041848 @default.
• W2885398889 hasAuthorship W2885398889A5064112154 @default.
• W2885398889 hasAuthorship W2885398889A5081851183 @default.
• W2885398889 hasAuthorship W2885398889A5086478424 @default.
• W2885398889 hasConcept C121608353 @default.
• W2885398889 hasConcept C126322002 @default.
• W2885398889 hasConcept C143998085 @default.
• W2885398889 hasConcept C2776534502 @default.
• W2885398889 hasConcept C61434518 @default.
• W2885398889 hasConcept C71924100 @default.
• W2885398889 hasConcept C72563966 @default.
• W2885398889 hasConceptScore W2885398889C121608353 @default.
• W2885398889 hasConceptScore W2885398889C126322002 @default.
• W2885398889 hasConceptScore W2885398889C143998085 @default.
• W2885398889 hasConceptScore W2885398889C2776534502 @default.
• W2885398889 hasConceptScore W2885398889C61434518 @default.
• W2885398889 hasConceptScore W2885398889C71924100 @default.
• W2885398889 hasConceptScore W2885398889C72563966 @default.
• W2885398889 hasLocation W28853988891 @default.
• W2885398889 hasOpenAccess W2885398889 @default.
• W2885398889 hasPrimaryLocation W28853988891 @default.
• W2885398889 hasRelatedWork W1540126543 @default.
• W2885398889 hasRelatedWork W1987750766 @default.
• W2885398889 hasRelatedWork W1990877187 @default.
• W2885398889 hasRelatedWork W2021994275 @default.
• W2885398889 hasRelatedWork W2030144132 @default.
• W2885398889 hasRelatedWork W2039908361 @default.
• W2885398889 hasRelatedWork W2171490057 @default.
• W2885398889 hasRelatedWork W2301059920 @default.
• W2885398889 hasRelatedWork W2315410755 @default.
• W2885398889 hasRelatedWork W2467321546 @default.
• W2885398889 hasRelatedWork W2491781680 @default.
• W2885398889 hasRelatedWork W2531016136 @default.
• W2885398889 hasRelatedWork W2800395784 @default.
• W2885398889 hasRelatedWork W2890718141 @default.
• W2885398889 hasRelatedWork W2902625302 @default.
• W2885398889 hasRelatedWork W2903525581 @default.
• W2885398889 hasRelatedWork W3023214584 @default.
• W2885398889 hasRelatedWork W3031555519 @default.
• W2885398889 hasRelatedWork W3129279343 @default.
• W2885398889 hasRelatedWork W344360006 @default.
• W2885398889 isParatext "false" @default.
• W2885398889 isRetracted "false" @default.
• W2885398889 magId "2885398889" @default.
• W2885398889 workType "article" @default.