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- W2885408841 abstract "Abstract Intestinal failure (IF) is the reduction of gut function or mass below a minimum needed to absorb nutrients and fluids, such that patients are dependent on parenteral nutrition (PN). Patients with IF have an altered gut microbiome. Our aim was to review and evaluate the current evidence on gut microbiome and its metabolic activity, as well as its association with disease characteristics in adults and children with IF. We performed a PubMed literature search for articles published after 2000 using the following terms: intestinal, microbiome, microbiota, short‐chain fatty acids, short bowel syndrome, and PN. Literature search was restricted to human studies only. The gut microbiome diversity is remarkably reduced, and community structure is altered with a noticeable overabundance of Proteobacteria, especially the Enterobacteriaceae family. A substantial increase in Lactobacillus level is often reported in patients with IF. Gut microbiome characteristics have been associated with poor growth, liver disease, D‐lactic acidosis, and duration of intestinal adaptation. Differences in microbiome characteristics have been found between patients receiving PN and those whose guts have adapted and have been weaned off PN. Future research with prospective sample collection should explore the value of the gut microbiome as a biomarker to guide clinical practice and as a modifiable therapeutic target to optimize outcomes of patients with IF." @default.
- W2885408841 created "2018-08-22" @default.
- W2885408841 creator A5003587274 @default.
- W2885408841 creator A5012101876 @default.
- W2885408841 creator A5017542174 @default.
- W2885408841 creator A5052193285 @default.
- W2885408841 creator A5060920572 @default.
- W2885408841 creator A5061642284 @default.
- W2885408841 creator A5075204358 @default.
- W2885408841 date "2018-08-02" @default.
- W2885408841 modified "2023-10-18" @default.
- W2885408841 title "The Gut Microbiome in Patients with Intestinal Failure: Current Evidence and Implications for Clinical Practice" @default.
- W2885408841 cites W1565524139 @default.
- W2885408841 cites W1607924216 @default.
- W2885408841 cites W1785063242 @default.
- W2885408841 cites W1877854700 @default.
- W2885408841 cites W1928531388 @default.
- W2885408841 cites W1963917835 @default.
- W2885408841 cites W1965291972 @default.
- W2885408841 cites W1967596657 @default.
- W2885408841 cites W1971691988 @default.
- W2885408841 cites W1977307485 @default.
- W2885408841 cites W1982696037 @default.
- W2885408841 cites W1984557560 @default.
- W2885408841 cites W1985640080 @default.
- W2885408841 cites W1985737277 @default.
- W2885408841 cites W1992621882 @default.
- W2885408841 cites W1992875107 @default.
- W2885408841 cites W1994103968 @default.
- W2885408841 cites W1997353969 @default.
- W2885408841 cites W2001997059 @default.
- W2885408841 cites W2002770287 @default.
- W2885408841 cites W2004506978 @default.
- W2885408841 cites W2005895469 @default.
- W2885408841 cites W2007110604 @default.
- W2885408841 cites W2010661146 @default.
- W2885408841 cites W2013482710 @default.
- W2885408841 cites W2014766007 @default.
- W2885408841 cites W2016444195 @default.
- W2885408841 cites W2016843129 @default.
- W2885408841 cites W2019130412 @default.
- W2885408841 cites W2028178959 @default.
- W2885408841 cites W2030232770 @default.
- W2885408841 cites W2030746522 @default.
- W2885408841 cites W2037108200 @default.
- W2885408841 cites W2049771483 @default.
- W2885408841 cites W2052969143 @default.
- W2885408841 cites W2055742804 @default.
- W2885408841 cites W2060485250 @default.
- W2885408841 cites W2070803377 @default.
- W2885408841 cites W2070879762 @default.
- W2885408841 cites W2071464172 @default.
- W2885408841 cites W2076621797 @default.
- W2885408841 cites W2076832266 @default.
- W2885408841 cites W2079809637 @default.
- W2885408841 cites W2083337853 @default.
- W2885408841 cites W2084831309 @default.
- W2885408841 cites W2085260006 @default.
- W2885408841 cites W2088781465 @default.
- W2885408841 cites W2090546766 @default.
- W2885408841 cites W2090711753 @default.
- W2885408841 cites W2093226662 @default.
- W2885408841 cites W2096891797 @default.
- W2885408841 cites W2097783355 @default.
- W2885408841 cites W2100503784 @default.
- W2885408841 cites W2101733634 @default.
- W2885408841 cites W2108124258 @default.
- W2885408841 cites W2109569804 @default.
- W2885408841 cites W2110235509 @default.
- W2885408841 cites W2110936821 @default.
- W2885408841 cites W2115396284 @default.
- W2885408841 cites W2118954244 @default.
- W2885408841 cites W2121279123 @default.
- W2885408841 cites W2126728659 @default.
- W2885408841 cites W2134100324 @default.
- W2885408841 cites W2134734167 @default.
- W2885408841 cites W2135717147 @default.
- W2885408841 cites W2137933122 @default.
- W2885408841 cites W2138997261 @default.
- W2885408841 cites W2144631364 @default.
- W2885408841 cites W2146624345 @default.
- W2885408841 cites W2149351690 @default.
- W2885408841 cites W2152751713 @default.
- W2885408841 cites W2161597130 @default.
- W2885408841 cites W2162088497 @default.
- W2885408841 cites W2167062509 @default.
- W2885408841 cites W2167200219 @default.
- W2885408841 cites W2167365461 @default.
- W2885408841 cites W2169330513 @default.
- W2885408841 cites W2183166216 @default.
- W2885408841 cites W2213612538 @default.
- W2885408841 cites W2281809897 @default.
- W2885408841 cites W2334675602 @default.
- W2885408841 cites W2472215855 @default.
- W2885408841 cites W2528349650 @default.
- W2885408841 cites W2550084345 @default.
- W2885408841 cites W2561294428 @default.
- W2885408841 cites W2582320162 @default.