Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885427810> ?p ?o ?g. }
- W2885427810 abstract "Altered metabolism in cancer cells is critical for tumor growth. One of the most notable aspects of this metabolic reprogramming lies in one-carbon metabolism. Cells require one carbon units for nucleotide synthesis, methylation reactions, and for the generation of reducing cofactors. Therefore, the ability to rewire and fine-tune one carbon metabolism is essential for the maintenance of cellular homeostasis. In this review, we describe how the major nutrient, energy, and redox sensors of the cell play a significant role in the regulation of flux through one carbon metabolism to enable cell fate decisions. We will also discuss how dysregulated oncogenic signaling hijacks these regulatory mechanisms to support and sustain high rates of proliferation and cell survival essential for tumor growth." @default.
- W2885427810 created "2018-08-22" @default.
- W2885427810 creator A5001671410 @default.
- W2885427810 creator A5019076582 @default.
- W2885427810 creator A5087327220 @default.
- W2885427810 date "2018-08-15" @default.
- W2885427810 modified "2023-10-14" @default.
- W2885427810 title "Beyond the Warburg Effect: How Do Cancer Cells Regulate One-Carbon Metabolism?" @default.
- W2885427810 cites W1831033366 @default.
- W2885427810 cites W1868543250 @default.
- W2885427810 cites W1890766043 @default.
- W2885427810 cites W1975770944 @default.
- W2885427810 cites W1980181091 @default.
- W2885427810 cites W1984328540 @default.
- W2885427810 cites W1987798277 @default.
- W2885427810 cites W1993238514 @default.
- W2885427810 cites W1996260337 @default.
- W2885427810 cites W1999251458 @default.
- W2885427810 cites W2000144783 @default.
- W2885427810 cites W2002015567 @default.
- W2885427810 cites W2002583208 @default.
- W2885427810 cites W2003783127 @default.
- W2885427810 cites W2014649668 @default.
- W2885427810 cites W2017035524 @default.
- W2885427810 cites W2020072016 @default.
- W2885427810 cites W2022899908 @default.
- W2885427810 cites W2025983003 @default.
- W2885427810 cites W2029862275 @default.
- W2885427810 cites W2031022790 @default.
- W2885427810 cites W2078410199 @default.
- W2885427810 cites W2080971278 @default.
- W2885427810 cites W2084968546 @default.
- W2885427810 cites W2095987251 @default.
- W2885427810 cites W2098972920 @default.
- W2885427810 cites W2108195113 @default.
- W2885427810 cites W2126524529 @default.
- W2885427810 cites W2143814205 @default.
- W2885427810 cites W2145912883 @default.
- W2885427810 cites W2159588477 @default.
- W2885427810 cites W2163404652 @default.
- W2885427810 cites W2168024298 @default.
- W2885427810 cites W2173466127 @default.
- W2885427810 cites W2181681557 @default.
- W2885427810 cites W2223535266 @default.
- W2885427810 cites W2225461623 @default.
- W2885427810 cites W2230238676 @default.
- W2885427810 cites W2253135181 @default.
- W2885427810 cites W2258318060 @default.
- W2885427810 cites W2262569734 @default.
- W2885427810 cites W2266570683 @default.
- W2885427810 cites W2326303021 @default.
- W2885427810 cites W2343452853 @default.
- W2885427810 cites W2405069786 @default.
- W2885427810 cites W2415945663 @default.
- W2885427810 cites W2519435458 @default.
- W2885427810 cites W2520894026 @default.
- W2885427810 cites W2539462439 @default.
- W2885427810 cites W2540090384 @default.
- W2885427810 cites W2588857040 @default.
- W2885427810 cites W2604932213 @default.
- W2885427810 cites W2611090362 @default.
- W2885427810 cites W2739502069 @default.
- W2885427810 cites W2767250022 @default.
- W2885427810 cites W2805815575 @default.
- W2885427810 cites W2999755403 @default.
- W2885427810 doi "https://doi.org/10.3389/fcell.2018.00090" @default.
- W2885427810 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6103474" @default.
- W2885427810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30159313" @default.
- W2885427810 hasPublicationYear "2018" @default.
- W2885427810 type Work @default.
- W2885427810 sameAs 2885427810 @default.
- W2885427810 citedByCount "77" @default.
- W2885427810 countsByYear W28854278102019 @default.
- W2885427810 countsByYear W28854278102020 @default.
- W2885427810 countsByYear W28854278102021 @default.
- W2885427810 countsByYear W28854278102022 @default.
- W2885427810 countsByYear W28854278102023 @default.
- W2885427810 crossrefType "journal-article" @default.
- W2885427810 hasAuthorship W2885427810A5001671410 @default.
- W2885427810 hasAuthorship W2885427810A5019076582 @default.
- W2885427810 hasAuthorship W2885427810A5087327220 @default.
- W2885427810 hasBestOaLocation W28854278101 @default.
- W2885427810 hasConcept C104317684 @default.
- W2885427810 hasConcept C109156525 @default.
- W2885427810 hasConcept C121608353 @default.
- W2885427810 hasConcept C1491633281 @default.
- W2885427810 hasConcept C150194340 @default.
- W2885427810 hasConcept C163952510 @default.
- W2885427810 hasConcept C179463898 @default.
- W2885427810 hasConcept C190727270 @default.
- W2885427810 hasConcept C2991704936 @default.
- W2885427810 hasConcept C41091548 @default.
- W2885427810 hasConcept C54355233 @default.
- W2885427810 hasConcept C55493867 @default.
- W2885427810 hasConcept C62112901 @default.
- W2885427810 hasConcept C62231903 @default.
- W2885427810 hasConcept C77255625 @default.
- W2885427810 hasConcept C86339819 @default.
- W2885427810 hasConcept C86803240 @default.
- W2885427810 hasConcept C95444343 @default.