Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885459502> ?p ?o ?g. }
- W2885459502 endingPage "16" @default.
- W2885459502 startingPage "1" @default.
- W2885459502 abstract "Stem cells (SCs) may constitute a perspective alternative to pharmacological treatment in neurodegenerative diseases. Although the safety of SC transplantation has been widely shown, their clinical efficiency in amyotrophic lateral sclerosis (ALS) is still to be proved. It is not only due to a limited number of studies, small treatment groups, and fast but nonlinear disease progression but also due to lack of objective methods able to show subtle clinical changes. Preliminary guidelines for cell therapy have recently been proposed by a group of ALS experts. They combine clinical, neurophysiological, and functional assessment together with monitoring of the cytokine level. Here, we describe a pilot study on transplantation of autologous adipose-derived regenerative cells (ADRC) into the spinal cord of the patients with ALS and monitoring of the results in accordance with the current recommendations. To show early and/or subtle changes within the muscles of interest, a wide range of clinical and functional tests were used and compared in order to choose the most sensitive and optimal set. Additionally, an analysis of transplanted ADRC was provided to develop standards ensuring the derivation and verification of adequate quality of transplanted cells and to correlate ADRC properties with clinical outcome." @default.
- W2885459502 created "2018-08-22" @default.
- W2885459502 creator A5000530451 @default.
- W2885459502 creator A5001897939 @default.
- W2885459502 creator A5004407630 @default.
- W2885459502 creator A5004550572 @default.
- W2885459502 creator A5018173987 @default.
- W2885459502 creator A5023768981 @default.
- W2885459502 creator A5027399423 @default.
- W2885459502 creator A5054788511 @default.
- W2885459502 creator A5060887988 @default.
- W2885459502 creator A5061590626 @default.
- W2885459502 creator A5068427427 @default.
- W2885459502 creator A5086838729 @default.
- W2885459502 date "2018-08-12" @default.
- W2885459502 modified "2023-10-18" @default.
- W2885459502 title "Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Optimal Monitoring Tools" @default.
- W2885459502 cites W1929098576 @default.
- W2885459502 cites W1972721105 @default.
- W2885459502 cites W1974551350 @default.
- W2885459502 cites W1974704788 @default.
- W2885459502 cites W1974886043 @default.
- W2885459502 cites W1978079465 @default.
- W2885459502 cites W1991117617 @default.
- W2885459502 cites W1994445653 @default.
- W2885459502 cites W2004008756 @default.
- W2885459502 cites W2006331513 @default.
- W2885459502 cites W2007478642 @default.
- W2885459502 cites W2008618128 @default.
- W2885459502 cites W2012402033 @default.
- W2885459502 cites W2013066063 @default.
- W2885459502 cites W2015037203 @default.
- W2885459502 cites W2016188552 @default.
- W2885459502 cites W2030962150 @default.
- W2885459502 cites W2045539431 @default.
- W2885459502 cites W2050394501 @default.
- W2885459502 cites W2052993959 @default.
- W2885459502 cites W2060583255 @default.
- W2885459502 cites W2061400823 @default.
- W2885459502 cites W2072562340 @default.
- W2885459502 cites W2076900766 @default.
- W2885459502 cites W2077764376 @default.
- W2885459502 cites W2083921296 @default.
- W2885459502 cites W2088742448 @default.
- W2885459502 cites W2089034809 @default.
- W2885459502 cites W2099525821 @default.
- W2885459502 cites W2113969375 @default.
- W2885459502 cites W2114242035 @default.
- W2885459502 cites W2119665388 @default.
- W2885459502 cites W2121675801 @default.
- W2885459502 cites W2121678953 @default.
- W2885459502 cites W2128768698 @default.
- W2885459502 cites W2134174819 @default.
- W2885459502 cites W2140248514 @default.
- W2885459502 cites W2148733415 @default.
- W2885459502 cites W2157811993 @default.
- W2885459502 cites W2159909434 @default.
- W2885459502 cites W2189492449 @default.
- W2885459502 cites W2266233401 @default.
- W2885459502 cites W2283100410 @default.
- W2885459502 cites W2321194932 @default.
- W2885459502 cites W2415775274 @default.
- W2885459502 cites W2515583816 @default.
- W2885459502 cites W2517929752 @default.
- W2885459502 cites W2528933357 @default.
- W2885459502 cites W2566446887 @default.
- W2885459502 cites W2607420694 @default.
- W2885459502 cites W2740906842 @default.
- W2885459502 cites W2746305815 @default.
- W2885459502 cites W2757056482 @default.
- W2885459502 cites W2761662444 @default.
- W2885459502 cites W2770575600 @default.
- W2885459502 cites W2973266615 @default.
- W2885459502 cites W3121771591 @default.
- W2885459502 cites W4248518818 @default.
- W2885459502 cites W80644426 @default.
- W2885459502 cites W878866150 @default.
- W2885459502 doi "https://doi.org/10.1155/2018/4392017" @default.
- W2885459502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6109475" @default.
- W2885459502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30158984" @default.
- W2885459502 hasPublicationYear "2018" @default.
- W2885459502 type Work @default.
- W2885459502 sameAs 2885459502 @default.
- W2885459502 citedByCount "12" @default.
- W2885459502 countsByYear W28854595022020 @default.
- W2885459502 countsByYear W28854595022021 @default.
- W2885459502 countsByYear W28854595022022 @default.
- W2885459502 countsByYear W28854595022023 @default.
- W2885459502 crossrefType "journal-article" @default.
- W2885459502 hasAuthorship W2885459502A5000530451 @default.
- W2885459502 hasAuthorship W2885459502A5001897939 @default.
- W2885459502 hasAuthorship W2885459502A5004407630 @default.
- W2885459502 hasAuthorship W2885459502A5004550572 @default.
- W2885459502 hasAuthorship W2885459502A5018173987 @default.
- W2885459502 hasAuthorship W2885459502A5023768981 @default.
- W2885459502 hasAuthorship W2885459502A5027399423 @default.
- W2885459502 hasAuthorship W2885459502A5054788511 @default.
- W2885459502 hasAuthorship W2885459502A5060887988 @default.