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- W2885478977 abstract "New thiazole nortopsentin analogues were conveniently synthesized and evaluated for their activity as inhibitors of biofilm formation of relevant Gram-positive and Gram-negative pathogens. All compounds were able to interfere with the first step of biofilm formation in a dose-dependent manner, showing a selectivity against the staphylococcal strains. The most active derivatives elicited IC50 values against Staphylococcus aureus ATCC 25923, ranging from 0.40–2.03 µM. The new compounds showed a typical anti-virulence profile, being able to inhibit the biofilm formation without affecting the microbial growth in the planktonic form." @default.
- W2885478977 created "2018-08-22" @default.
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- W2885478977 date "2018-08-04" @default.
- W2885478977 modified "2023-10-17" @default.
- W2885478977 title "New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation" @default.
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- W2885478977 doi "https://doi.org/10.3390/md16080274" @default.
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