FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885655344> ?p ?o ?g. }

• W2885655344 endingPage "283" @default.
• W2885655344 startingPage "277" @default.
• W2885655344 abstract "This study investigated the prevalence of haplotypes of the Pfdhps, Pfdhfr, Pfcrt, Pfmdr1 and PfK13 resistance markers in isolates from asymptomatic patients from the Republic of the Congo following implementation of artemisinin based-combination therapy (ACT). Peripheral blood was collected from asymptomatic children in 2010 and 2015 from Brazzaville in the south and in 2013 in the north of the Congo. Genotypes of Pfmdr1, Pfcrt, Pfdhps, Pfdhfr and PfK13 were assessed by PCR. Children from 2010 were younger than those from 2015 (mean age 5.38 years vs. 8.67 years; P = 0.003). The main Pfcrt haplotype was the wild-type CVMNK (84.85%) in 2010, whereas the mutant CVIET (61.64%) predominated in 2015 (P < 0.001). In the north, 45.00% of samples were CVMNK and 10.00% were CVIET. Other samples harboured new haplotypes in the country or mixed alleles. No significant difference in Pfmdr1 haplotypes was observed in 2010 and 2015 and the main haplotypes were NYD and NFD (30.56% vs. 28.57% and 61.11% vs. 42.86% for 2010 and 2015, respectively). In the south, the Pfdhps haplotypes observed were AAKAA, AGKAA, SGKAA and SGEGA (87.50% vs. 0%, 12.50% vs. 33.33%, 0% vs. 33.33% and 0% vs. 33.33% for 2010 and 2015, respectively). For Pfdhfr, the IRNI haplotype was most prevalent (85.71% for 2010, 87.50% for 2013 and 100% for 2015). No PfK13 mutations were found. Monitoring the efficacy of ACT and intermittent preventive treatment with sulfadoxine–pyrimethamine is necessary to ensure an epidemiological survey of asymptomatic malaria." @default.
• W2885655344 created "2018-08-22" @default.
• W2885655344 creator A5008051493 @default.
• W2885655344 creator A5047903439 @default.
• W2885655344 creator A5067117243 @default.
• W2885655344 creator A5078098543 @default.
• W2885655344 creator A5090698178 @default.
• W2885655344 creator A5090897635 @default.
• W2885655344 date "2018-09-01" @default.
• W2885655344 modified "2023-10-17" @default.
• W2885655344 title "High prevalence of Plasmodium falciparum antimalarial drug resistance markers in isolates from asymptomatic patients from the Republic of the Congo between 2010 and 2015" @default.
• W2885655344 cites W1594650890 @default.
• W2885655344 cites W1737756073 @default.
• W2885655344 cites W1994840465 @default.
• W2885655344 cites W1996917976 @default.
• W2885655344 cites W2005682005 @default.
• W2885655344 cites W2019358007 @default.
• W2885655344 cites W2023818253 @default.
• W2885655344 cites W2027820089 @default.
• W2885655344 cites W2033950979 @default.
• W2885655344 cites W2040815124 @default.
• W2885655344 cites W2056979654 @default.
• W2885655344 cites W2060499851 @default.
• W2885655344 cites W2070239562 @default.
• W2885655344 cites W2075453057 @default.
• W2885655344 cites W2099633875 @default.
• W2885655344 cites W2101842428 @default.
• W2885655344 cites W2102395543 @default.
• W2885655344 cites W2103631590 @default.
• W2885655344 cites W2104361833 @default.
• W2885655344 cites W2110269548 @default.
• W2885655344 cites W2113584005 @default.
• W2885655344 cites W2113703059 @default.
• W2885655344 cites W2114213072 @default.
• W2885655344 cites W2124634096 @default.
• W2885655344 cites W2129159324 @default.
• W2885655344 cites W2137636253 @default.
• W2885655344 cites W2137890602 @default.
• W2885655344 cites W2143754068 @default.
• W2885655344 cites W2148673502 @default.
• W2885655344 cites W2153542611 @default.
• W2885655344 cites W2157765820 @default.
• W2885655344 cites W2161023750 @default.
• W2885655344 cites W2163765308 @default.
• W2885655344 cites W2165336268 @default.
• W2885655344 cites W2169401483 @default.
• W2885655344 cites W2187324237 @default.
• W2885655344 cites W2201549738 @default.
• W2885655344 cites W2217179860 @default.
• W2885655344 cites W2231322307 @default.
• W2885655344 cites W2252644184 @default.
• W2885655344 cites W2277920228 @default.
• W2885655344 cites W2311216236 @default.
• W2885655344 cites W2397788564 @default.
• W2885655344 cites W2418989184 @default.
• W2885655344 cites W2467259677 @default.
• W2885655344 cites W2471559361 @default.
• W2885655344 cites W2473053262 @default.
• W2885655344 cites W2507678567 @default.
• W2885655344 cites W2507983450 @default.
• W2885655344 cites W2548352768 @default.
• W2885655344 cites W2564807717 @default.
• W2885655344 cites W2581554421 @default.
• W2885655344 cites W2590767446 @default.
• W2885655344 cites W2591034133 @default.
• W2885655344 cites W2605400261 @default.
• W2885655344 cites W2608549546 @default.
• W2885655344 cites W2609143407 @default.
• W2885655344 cites W2613173822 @default.
• W2885655344 cites W622810663 @default.
• W2885655344 doi "https://doi.org/10.1016/j.jgar.2018.08.003" @default.
• W2885655344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30121345" @default.
• W2885655344 hasPublicationYear "2018" @default.
• W2885655344 type Work @default.
• W2885655344 sameAs 2885655344 @default.
• W2885655344 citedByCount "5" @default.
• W2885655344 countsByYear W28856553442021 @default.
• W2885655344 countsByYear W28856553442022 @default.
• W2885655344 countsByYear W28856553442023 @default.
• W2885655344 crossrefType "journal-article" @default.
• W2885655344 hasAuthorship W2885655344A5008051493 @default.
• W2885655344 hasAuthorship W2885655344A5047903439 @default.
• W2885655344 hasAuthorship W2885655344A5067117243 @default.
• W2885655344 hasAuthorship W2885655344A5078098543 @default.
• W2885655344 hasAuthorship W2885655344A5090698178 @default.
• W2885655344 hasAuthorship W2885655344A5090897635 @default.
• W2885655344 hasConcept C104317684 @default.
• W2885655344 hasConcept C114851261 @default.
• W2885655344 hasConcept C126322002 @default.
• W2885655344 hasConcept C135763542 @default.
• W2885655344 hasConcept C159047783 @default.
• W2885655344 hasConcept C197754878 @default.
• W2885655344 hasConcept C203014093 @default.
• W2885655344 hasConcept C2777035104 @default.
• W2885655344 hasConcept C2777234095 @default.
• W2885655344 hasConcept C2777910003 @default.
• W2885655344 hasConcept C2778048844 @default.
• W2885655344 hasConcept C2778371730 @default.

• next