FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885663991> ?p ?o ?g. }

• W2885663991 abstract "OBJECTIVES: We assessed the adherence to neuroimaging guidelines and the diagnostically relevant yield of neuroimaging in newly presenting early life epilepsy (ELE). METHODS: There were 775 children with a new diagnosis of epilepsy (&lt;3 years old at onset) who were recruited through the ELE study at 17 US pediatric epilepsy centers (2012–2015) and managed prospectively for 1 year. The data were analyzed to assess the proportion of children who underwent neuroimaging, the type of neuroimaging, and abnormalities. RESULTS: Of 725 children (93.5%) with neuroimaging, 714 had an MRI (87% with seizure protocols) and 11 had computed tomography or ultrasound only. Etiologically relevant abnormalities were present in 290 individuals (40%) and included: an acquired injury in 97 (13.4%), malformations of cortical development in 56 (7.7%), and other diffuse disorders of brain development in 51 (7.0%). Neuroimaging was abnormal in 160 of 262 (61%) children with abnormal development at diagnosis versus 113 of 463 (24%) children with typical development. Neuroimaging abnormalities were most common in association with focal seizure semiology (40%), spasms (47%), or unclear semiology (42%). In children without spasms or focal semiology with typical development, 29 of 185 (16%) had imaging abnormalities. Pathogenic genetic variants were identified in 53 of 121 (44%) children with abnormal neuroimaging in whom genetic testing was performed. CONCLUSIONS: Structural abnormalities occur commonly in ELE, and adherence to neuroimaging guidelines is high at US pediatric epilepsy centers. These data support the universal adoption of imaging guidelines because the yield is substantially high, even in the lowest risk group." @default.
• W2885663991 created "2018-08-22" @default.
• W2885663991 creator A5008809086 @default.
• W2885663991 creator A5010524322 @default.
• W2885663991 creator A5023160396 @default.
• W2885663991 creator A5027898537 @default.
• W2885663991 creator A5031681045 @default.
• W2885663991 creator A5038960596 @default.
• W2885663991 creator A5045461985 @default.
• W2885663991 creator A5045710013 @default.
• W2885663991 creator A5046645524 @default.
• W2885663991 creator A5047125763 @default.
• W2885663991 creator A5047502918 @default.
• W2885663991 creator A5057683673 @default.
• W2885663991 creator A5061637515 @default.
• W2885663991 creator A5063219454 @default.
• W2885663991 creator A5066978144 @default.
• W2885663991 creator A5087393333 @default.
• W2885663991 date "2018-09-01" @default.
• W2885663991 modified "2023-10-18" @default.
• W2885663991 title "Neuroimaging of Early Life Epilepsy" @default.
• W2885663991 cites W1421011500 @default.
• W2885663991 cites W1483461087 @default.
• W2885663991 cites W1940036272 @default.
• W2885663991 cites W1978437325 @default.
• W2885663991 cites W1988940197 @default.
• W2885663991 cites W1996189984 @default.
• W2885663991 cites W2031186730 @default.
• W2885663991 cites W2045023557 @default.
• W2885663991 cites W2045854231 @default.
• W2885663991 cites W2046002803 @default.
• W2885663991 cites W2052073709 @default.
• W2885663991 cites W2080289801 @default.
• W2885663991 cites W2085476870 @default.
• W2885663991 cites W2093274439 @default.
• W2885663991 cites W2108997250 @default.
• W2885663991 cites W2125496002 @default.
• W2885663991 cites W2132352566 @default.
• W2885663991 cites W2140806988 @default.
• W2885663991 cites W2141754028 @default.
• W2885663991 cites W2143526653 @default.
• W2885663991 cites W2168841659 @default.
• W2885663991 cites W2286015474 @default.
• W2885663991 cites W2297732712 @default.
• W2885663991 cites W2331255447 @default.
• W2885663991 cites W2396577307 @default.
• W2885663991 cites W2427665531 @default.
• W2885663991 cites W2511110663 @default.
• W2885663991 cites W2516639160 @default.
• W2885663991 cites W2587436922 @default.
• W2885663991 cites W2604355298 @default.
• W2885663991 cites W2604469091 @default.
• W2885663991 cites W2740338895 @default.
• W2885663991 doi "https://doi.org/10.1542/peds.2018-0672" @default.
• W2885663991 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6510984" @default.
• W2885663991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30089657" @default.
• W2885663991 hasPublicationYear "2018" @default.
• W2885663991 type Work @default.
• W2885663991 sameAs 2885663991 @default.
• W2885663991 citedByCount "20" @default.
• W2885663991 countsByYear W28856639912019 @default.
• W2885663991 countsByYear W28856639912020 @default.
• W2885663991 countsByYear W28856639912021 @default.
• W2885663991 countsByYear W28856639912022 @default.
• W2885663991 countsByYear W28856639912023 @default.
• W2885663991 crossrefType "journal-article" @default.
• W2885663991 hasAuthorship W2885663991A5008809086 @default.
• W2885663991 hasAuthorship W2885663991A5010524322 @default.
• W2885663991 hasAuthorship W2885663991A5023160396 @default.
• W2885663991 hasAuthorship W2885663991A5027898537 @default.
• W2885663991 hasAuthorship W2885663991A5031681045 @default.
• W2885663991 hasAuthorship W2885663991A5038960596 @default.
• W2885663991 hasAuthorship W2885663991A5045461985 @default.
• W2885663991 hasAuthorship W2885663991A5045710013 @default.
• W2885663991 hasAuthorship W2885663991A5046645524 @default.
• W2885663991 hasAuthorship W2885663991A5047125763 @default.
• W2885663991 hasAuthorship W2885663991A5047502918 @default.
• W2885663991 hasAuthorship W2885663991A5057683673 @default.
• W2885663991 hasAuthorship W2885663991A5061637515 @default.
• W2885663991 hasAuthorship W2885663991A5063219454 @default.
• W2885663991 hasAuthorship W2885663991A5066978144 @default.
• W2885663991 hasAuthorship W2885663991A5087393333 @default.
• W2885663991 hasBestOaLocation W28856639911 @default.
• W2885663991 hasConcept C118552586 @default.
• W2885663991 hasConcept C187212893 @default.
• W2885663991 hasConcept C198951751 @default.
• W2885663991 hasConcept C2778186239 @default.
• W2885663991 hasConcept C58693492 @default.
• W2885663991 hasConcept C71924100 @default.
• W2885663991 hasConceptScore W2885663991C118552586 @default.
• W2885663991 hasConceptScore W2885663991C187212893 @default.
• W2885663991 hasConceptScore W2885663991C198951751 @default.
• W2885663991 hasConceptScore W2885663991C2778186239 @default.
• W2885663991 hasConceptScore W2885663991C58693492 @default.
• W2885663991 hasConceptScore W2885663991C71924100 @default.
• W2885663991 hasIssue "3" @default.
• W2885663991 hasLocation W28856639911 @default.
• W2885663991 hasLocation W28856639912 @default.
• W2885663991 hasLocation W28856639913 @default.
• W2885663991 hasLocation W28856639914 @default.

• next