Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885674246> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2885674246 endingPage "464" @default.
- W2885674246 startingPage "458" @default.
- W2885674246 abstract "Excess iron (Fe) intake in subjects carrying certain mutations in the HFE gene may result in Fe overload. To estimate risk of Fe overload, 166 male blood donors (19-65 years) from Buenos Aires city were investigated. Daily Fe intake (FeI), hem Fe intake, and Fe intake from SO4Fe enriched flours were estimated (SARA Computer Program and Food Composition Table, USDA). Serum ferritin and transferrin saturation were determined; criteria for Fe overload was serum ferritin > 300 ng/ml and transferrin saturation = 50%. HFE genotypes C282Y, H63D and S65C were analyzed by PCR-RFLP in blood samples. No participant presented FeI lower than the estimated average requirement (6 mg Fe/day) and 3.0% was over the upper level (45 mg Fe/day). Hem Fe and Fe from flour enrichment were 9.4% and 47.7% of daily Fe intake, respectively. A significant association was observed between the increase in serum ferritin (ng/ml) and the increase in FeI (p = 0.0472); 2.3% of the donors presented serum ferritin > 300 ng/ml and transferrin saturation = 50%. Genotypes associated with hereditary hemochromatosis (H63D, S65C and C282Y) were found in 29.3% of the donors. The percentage of transferrin saturation was higher in subjects carrying mutation than in wild type subjects (p = 0.0167). Although penetrance of hereditary hemochromatosis in the studied group was only 1.2%, an excessive Fe intake could enhance adverse effects in individuals unaware of any family history of Fe overload." @default.
- W2885674246 created "2018-08-22" @default.
- W2885674246 creator A5000245406 @default.
- W2885674246 creator A5009446018 @default.
- W2885674246 creator A5017333260 @default.
- W2885674246 creator A5037647539 @default.
- W2885674246 creator A5065440557 @default.
- W2885674246 creator A5068040241 @default.
- W2885674246 creator A5069867136 @default.
- W2885674246 creator A5078090774 @default.
- W2885674246 creator A5089092715 @default.
- W2885674246 date "2017-12-11" @default.
- W2885674246 modified "2023-10-14" @default.
- W2885674246 title "[Iron intake and HFE gen in male adults from Buenos Aires]." @default.
- W2885674246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29223935" @default.
- W2885674246 hasPublicationYear "2017" @default.
- W2885674246 type Work @default.
- W2885674246 sameAs 2885674246 @default.
- W2885674246 citedByCount "0" @default.
- W2885674246 crossrefType "journal-article" @default.
- W2885674246 hasAuthorship W2885674246A5000245406 @default.
- W2885674246 hasAuthorship W2885674246A5009446018 @default.
- W2885674246 hasAuthorship W2885674246A5017333260 @default.
- W2885674246 hasAuthorship W2885674246A5037647539 @default.
- W2885674246 hasAuthorship W2885674246A5065440557 @default.
- W2885674246 hasAuthorship W2885674246A5068040241 @default.
- W2885674246 hasAuthorship W2885674246A5069867136 @default.
- W2885674246 hasAuthorship W2885674246A5078090774 @default.
- W2885674246 hasAuthorship W2885674246A5089092715 @default.
- W2885674246 hasConcept C104317684 @default.
- W2885674246 hasConcept C126322002 @default.
- W2885674246 hasConcept C127716648 @default.
- W2885674246 hasConcept C134018914 @default.
- W2885674246 hasConcept C135763542 @default.
- W2885674246 hasConcept C140793950 @default.
- W2885674246 hasConcept C153852466 @default.
- W2885674246 hasConcept C185592680 @default.
- W2885674246 hasConcept C200544954 @default.
- W2885674246 hasConcept C22814914 @default.
- W2885674246 hasConcept C2776244011 @default.
- W2885674246 hasConcept C2776590208 @default.
- W2885674246 hasConcept C2777357209 @default.
- W2885674246 hasConcept C2777417653 @default.
- W2885674246 hasConcept C2778248108 @default.
- W2885674246 hasConcept C2778319317 @default.
- W2885674246 hasConcept C2779875672 @default.
- W2885674246 hasConcept C3017702006 @default.
- W2885674246 hasConcept C3018783601 @default.
- W2885674246 hasConcept C3019184707 @default.
- W2885674246 hasConcept C55493867 @default.
- W2885674246 hasConcept C71924100 @default.
- W2885674246 hasConcept C86803240 @default.
- W2885674246 hasConceptScore W2885674246C104317684 @default.
- W2885674246 hasConceptScore W2885674246C126322002 @default.
- W2885674246 hasConceptScore W2885674246C127716648 @default.
- W2885674246 hasConceptScore W2885674246C134018914 @default.
- W2885674246 hasConceptScore W2885674246C135763542 @default.
- W2885674246 hasConceptScore W2885674246C140793950 @default.
- W2885674246 hasConceptScore W2885674246C153852466 @default.
- W2885674246 hasConceptScore W2885674246C185592680 @default.
- W2885674246 hasConceptScore W2885674246C200544954 @default.
- W2885674246 hasConceptScore W2885674246C22814914 @default.
- W2885674246 hasConceptScore W2885674246C2776244011 @default.
- W2885674246 hasConceptScore W2885674246C2776590208 @default.
- W2885674246 hasConceptScore W2885674246C2777357209 @default.
- W2885674246 hasConceptScore W2885674246C2777417653 @default.
- W2885674246 hasConceptScore W2885674246C2778248108 @default.
- W2885674246 hasConceptScore W2885674246C2778319317 @default.
- W2885674246 hasConceptScore W2885674246C2779875672 @default.
- W2885674246 hasConceptScore W2885674246C3017702006 @default.
- W2885674246 hasConceptScore W2885674246C3018783601 @default.
- W2885674246 hasConceptScore W2885674246C3019184707 @default.
- W2885674246 hasConceptScore W2885674246C55493867 @default.
- W2885674246 hasConceptScore W2885674246C71924100 @default.
- W2885674246 hasConceptScore W2885674246C86803240 @default.
- W2885674246 hasIssue "6" @default.
- W2885674246 hasLocation W28856742461 @default.
- W2885674246 hasOpenAccess W2885674246 @default.
- W2885674246 hasPrimaryLocation W28856742461 @default.
- W2885674246 hasRelatedWork W2024183011 @default.
- W2885674246 hasRelatedWork W2075666380 @default.
- W2885674246 hasRelatedWork W2090631947 @default.
- W2885674246 hasRelatedWork W2170379620 @default.
- W2885674246 hasRelatedWork W2191078196 @default.
- W2885674246 hasRelatedWork W2336897735 @default.
- W2885674246 hasRelatedWork W2397710185 @default.
- W2885674246 hasRelatedWork W2415470286 @default.
- W2885674246 hasRelatedWork W2748779067 @default.
- W2885674246 hasRelatedWork W2885674246 @default.
- W2885674246 hasVolume "77" @default.
- W2885674246 isParatext "false" @default.
- W2885674246 isRetracted "false" @default.
- W2885674246 magId "2885674246" @default.
- W2885674246 workType "article" @default.