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- W2885679903 abstract "Purpose of review Optical coherence tomography (OCT) is a noninvasive in-vivo imaging tool that enables the quantification of the various retinal layer thicknesses. Given the frequent involvement of the visual pathway in multiple sclerosis, OCT has become an important tool in clinical practice, research and clinical trials. In this review, the role of OCT as a means to investigate visual pathway damage in multiple sclerosis is discussed. Recent findings Evidence from recent OCT studies suggests that the peripapillary retinal nerve fibre layer (pRNFL) appears to be an ideal marker of axonal integrity, whereas the macular ganglion cell and inner plexiform layer (GCIP) thickness enables early detection of neuronal degeneration in multiple sclerosis. The thickness of the macular inner nuclear layer (INL) has been suggested as a biomarker for inflammatory disease activity and treatment response in multiple sclerosis. OCT parameters may also be used as an outcome measure in clinical trials evaluating the neuroprotective or regenerative potential of new treatments. Summary OCT provides insights into multiple sclerosis beyond the visual pathway. It is capable of quantifying the major pathological hallmarks of the disease, specifically inflammation and neuroaxonal degeneration. OCT, therefore, has the potential to become another mainstay in the monitoring of multiple sclerosis patients." @default.
- W2885679903 created "2018-08-22" @default.
- W2885679903 creator A5005005782 @default.
- W2885679903 creator A5059715038 @default.
- W2885679903 creator A5071972650 @default.
- W2885679903 date "2018-10-01" @default.
- W2885679903 modified "2023-09-27" @default.
- W2885679903 title "Optical coherence tomography as a means to characterize visual pathway involvement in multiple sclerosis" @default.
- W2885679903 cites W1018609964 @default.
- W2885679903 cites W1176340840 @default.
- W2885679903 cites W1828579964 @default.
- W2885679903 cites W1914231371 @default.
- W2885679903 cites W1955700682 @default.
- W2885679903 cites W1976692470 @default.
- W2885679903 cites W1976987174 @default.
- W2885679903 cites W1987686429 @default.
- W2885679903 cites W1989300952 @default.
- W2885679903 cites W1994187238 @default.
- W2885679903 cites W1998337039 @default.
- W2885679903 cites W1998770539 @default.
- W2885679903 cites W2000511084 @default.
- W2885679903 cites W2001110565 @default.
- W2885679903 cites W2001353970 @default.
- W2885679903 cites W2006175679 @default.
- W2885679903 cites W2011920655 @default.
- W2885679903 cites W2014127183 @default.
- W2885679903 cites W2014662952 @default.
- W2885679903 cites W2032225444 @default.
- W2885679903 cites W2035237217 @default.
- W2885679903 cites W2045760303 @default.
- W2885679903 cites W2049116186 @default.
- W2885679903 cites W2058728896 @default.
- W2885679903 cites W2061232461 @default.
- W2885679903 cites W2073337321 @default.
- W2885679903 cites W2075584671 @default.
- W2885679903 cites W2078870028 @default.
- W2885679903 cites W2083953072 @default.
- W2885679903 cites W2085015483 @default.
- W2885679903 cites W2086091627 @default.
- W2885679903 cites W2089416663 @default.
- W2885679903 cites W2105160857 @default.
- W2885679903 cites W2112165124 @default.
- W2885679903 cites W2113570523 @default.
- W2885679903 cites W2113922996 @default.
- W2885679903 cites W2115404493 @default.
- W2885679903 cites W2118698089 @default.
- W2885679903 cites W2122237804 @default.
- W2885679903 cites W2123272497 @default.
- W2885679903 cites W2125442932 @default.
- W2885679903 cites W2127294620 @default.
- W2885679903 cites W2134146036 @default.
- W2885679903 cites W2144665769 @default.
- W2885679903 cites W2149842240 @default.
- W2885679903 cites W2150727535 @default.
- W2885679903 cites W2158156478 @default.
- W2885679903 cites W2164167069 @default.
- W2885679903 cites W2259890370 @default.
- W2885679903 cites W2296989255 @default.
- W2885679903 cites W2332147189 @default.
- W2885679903 cites W2341992171 @default.
- W2885679903 cites W2342723896 @default.
- W2885679903 cites W2344036133 @default.
- W2885679903 cites W2346486456 @default.
- W2885679903 cites W2401147790 @default.
- W2885679903 cites W2488489648 @default.
- W2885679903 cites W2513121168 @default.
- W2885679903 cites W2542372902 @default.
- W2885679903 cites W2547149500 @default.
- W2885679903 cites W2554521349 @default.
- W2885679903 cites W2556492862 @default.
- W2885679903 cites W2557324930 @default.
- W2885679903 cites W2559770979 @default.
- W2885679903 cites W2587776950 @default.
- W2885679903 cites W2588929689 @default.
- W2885679903 cites W2611399534 @default.
- W2885679903 cites W2734567073 @default.
- W2885679903 cites W2734838155 @default.
- W2885679903 cites W2755106885 @default.
- W2885679903 cites W2768693546 @default.
- W2885679903 cites W2769641274 @default.
- W2885679903 cites W2770823650 @default.
- W2885679903 cites W2774768051 @default.
- W2885679903 cites W2774907396 @default.
- W2885679903 cites W2784725334 @default.
- W2885679903 cites W2789696708 @default.
- W2885679903 cites W4211229404 @default.
- W2885679903 cites W4233230329 @default.
- W2885679903 doi "https://doi.org/10.1097/wco.0000000000000604" @default.
- W2885679903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30074495" @default.
- W2885679903 hasPublicationYear "2018" @default.
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