Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885686904> ?p ?o ?g. }
- W2885686904 endingPage "2139" @default.
- W2885686904 startingPage "2130" @default.
- W2885686904 abstract "Convergent evolution, a process by which organisms evolved independently to have similar traits, provides opportunities to understand adaptation. The bacterial genus Mycoplasma contains multiple species that evolved independently to become ruminant pathogens, which represents an interesting study system for investigating the process. In this work, we determined the genome sequences of 11 Entomoplasma/Mesoplasma species. This new data set, together with the other available Mollicutes genomes, provided comprehensive taxon sampling for inferring the gene content evolution that led to the emergence of Mycoplasma Mycoides cluster. Our results indicated that the most recent common ancestor (MRCA) of the Mycoides-Entomoplasmataceae clade lost ∼15% of the core genes when it diverged from the Spiroplasma Apis clade. After this initial wave of genome reduction, relatively few gene gains or losses were inferred until the emergence of the Mycoides cluster. Compared with those Entomoplasmataceae lineages that maintained the association with insects, the MRCA of the Mycoides cluster experienced a second wave of gene losses, as well as acquiring >100 novel genes through horizontal gene transfer. These gene acquisitions involved many with the Mycoplasma Hominis/Pneumoniae lineages as the putative donors, suggesting that gene exchanges among these vertebrate symbionts with distinct phylogenetic affiliations may be important in the emergence of the Mycoides cluster. These findings demonstrated that the gene content of bacterial genomes could be exceedingly dynamic, even for those symbionts with highly reduced genomes. Moreover, the emergence of novel pathogens may involve extensive remodeling of gene content, rather than acquisition of few virulence genes." @default.
- W2885686904 created "2018-08-22" @default.
- W2885686904 creator A5045937455 @default.
- W2885686904 creator A5089947499 @default.
- W2885686904 creator A5090743830 @default.
- W2885686904 date "2018-08-01" @default.
- W2885686904 modified "2023-10-17" @default.
- W2885686904 title "Convergent Evolution among Ruminant-Pathogenic Mycoplasma Involved Extensive Gene Content Changes" @default.
- W2885686904 cites W104710838 @default.
- W2885686904 cites W132558396 @default.
- W2885686904 cites W1962562500 @default.
- W2885686904 cites W1978211025 @default.
- W2885686904 cites W1979340524 @default.
- W2885686904 cites W1981490019 @default.
- W2885686904 cites W1988266391 @default.
- W2885686904 cites W2008426717 @default.
- W2885686904 cites W2008856488 @default.
- W2885686904 cites W2016588572 @default.
- W2885686904 cites W2017174771 @default.
- W2885686904 cites W2033623058 @default.
- W2885686904 cites W2045843097 @default.
- W2885686904 cites W2058727654 @default.
- W2885686904 cites W2083706719 @default.
- W2885686904 cites W2087936385 @default.
- W2885686904 cites W2092604303 @default.
- W2885686904 cites W2092611193 @default.
- W2885686904 cites W2096198365 @default.
- W2885686904 cites W2098824795 @default.
- W2885686904 cites W2102294866 @default.
- W2885686904 cites W2102327254 @default.
- W2885686904 cites W2103546861 @default.
- W2885686904 cites W2106265368 @default.
- W2885686904 cites W2108374645 @default.
- W2885686904 cites W2115453787 @default.
- W2885686904 cites W2119552198 @default.
- W2885686904 cites W2119585200 @default.
- W2885686904 cites W2132260246 @default.
- W2885686904 cites W2132926880 @default.
- W2885686904 cites W2133707124 @default.
- W2885686904 cites W2133991766 @default.
- W2885686904 cites W2136735575 @default.
- W2885686904 cites W2142343836 @default.
- W2885686904 cites W2142678478 @default.
- W2885686904 cites W2143485490 @default.
- W2885686904 cites W2145340597 @default.
- W2885686904 cites W2146058063 @default.
- W2885686904 cites W2149429041 @default.
- W2885686904 cites W2160969485 @default.
- W2885686904 cites W2163195450 @default.
- W2885686904 cites W2178043251 @default.
- W2885686904 cites W2291091413 @default.
- W2885686904 cites W2304674135 @default.
- W2885686904 cites W2516492912 @default.
- W2885686904 cites W2604179415 @default.
- W2885686904 cites W2623492145 @default.
- W2885686904 cites W2754801723 @default.
- W2885686904 cites W2766713621 @default.
- W2885686904 cites W2769931760 @default.
- W2885686904 cites W2793538517 @default.
- W2885686904 cites W2797330238 @default.
- W2885686904 cites W2807369229 @default.
- W2885686904 cites W2889019390 @default.
- W2885686904 cites W4238426924 @default.
- W2885686904 cites W4255659575 @default.
- W2885686904 doi "https://doi.org/10.1093/gbe/evy172" @default.
- W2885686904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6117150" @default.
- W2885686904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30102350" @default.
- W2885686904 hasPublicationYear "2018" @default.
- W2885686904 type Work @default.
- W2885686904 sameAs 2885686904 @default.
- W2885686904 citedByCount "28" @default.
- W2885686904 countsByYear W28856869042019 @default.
- W2885686904 countsByYear W28856869042020 @default.
- W2885686904 countsByYear W28856869042021 @default.
- W2885686904 countsByYear W28856869042022 @default.
- W2885686904 countsByYear W28856869042023 @default.
- W2885686904 crossrefType "journal-article" @default.
- W2885686904 hasAuthorship W2885686904A5045937455 @default.
- W2885686904 hasAuthorship W2885686904A5089947499 @default.
- W2885686904 hasAuthorship W2885686904A5090743830 @default.
- W2885686904 hasBestOaLocation W28856869041 @default.
- W2885686904 hasConcept C104317684 @default.
- W2885686904 hasConcept C141231307 @default.
- W2885686904 hasConcept C193252679 @default.
- W2885686904 hasConcept C197583594 @default.
- W2885686904 hasConcept C2775881110 @default.
- W2885686904 hasConcept C2776302332 @default.
- W2885686904 hasConcept C2778838687 @default.
- W2885686904 hasConcept C2778961482 @default.
- W2885686904 hasConcept C2780464796 @default.
- W2885686904 hasConcept C36857842 @default.
- W2885686904 hasConcept C44465124 @default.
- W2885686904 hasConcept C54355233 @default.
- W2885686904 hasConcept C62142553 @default.
- W2885686904 hasConcept C78458016 @default.
- W2885686904 hasConcept C86803240 @default.
- W2885686904 hasConcept C90132467 @default.
- W2885686904 hasConcept C92938381 @default.