FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885702325> ?p ?o ?g. }

• W2885702325 abstract "Hepatocyte growth factor (HGF) is a potent angiogenic polypeptide that stimulates angiogenesis. Transcriptional regulation of HGF, however, has not been fully defined, with the exception of the hypoxia-mediated downregulation in cultured cells. In the present study, we report that angiogenic growth factors, including HGF, were upregulated in a murine model of critical limb ischemia in vivo, a finding that was in conflict with previous in vitro data. Mice deficient in basic fibroblast growth factor-2 (FGF-2) showed reduced induction of HGF protein in ischemic muscles, and overexpression of FGF-2 via gene transfer stimulated endogenous HGF, irrespective of the presence of ischemia. In culture, FGF-2 rapidly stimulated HGF mRNA, and a sustained expression was evident in the time course in vascular smooth muscle cells and fibroblasts. FGF-2–mediated induction of HGF was fully dependent on the mitogen-activated protein kinase pathway yet was not affected by either hypoxia or a protein kinase A inhibitor. In th..." @default.
• W2885702325 created "2018-08-22" @default.
• W2885702325 creator A5003827108 @default.
• W2885702325 creator A5006049703 @default.
• W2885702325 creator A5010407648 @default.
• W2885702325 creator A5014511041 @default.
• W2885702325 creator A5018943952 @default.
• W2885702325 creator A5030498911 @default.
• W2885702325 creator A5052799646 @default.
• W2885702325 creator A5061607767 @default.
• W2885702325 creator A5067739320 @default.
• W2885702325 creator A5081455161 @default.
• W2885702325 date "2002-11-15" @default.
• W2885702325 modified "2023-09-28" @default.
• W2885702325 title "Fibroblast Growth Factor-2 Gene Transfer Can Stimulate Hepatocyte Growth Factor Expression Irrespective of Hypoxia-Mediated Downregulation in Ischemic Limbs" @default.
• W2885702325 hasPublicationYear "2002" @default.
• W2885702325 type Work @default.
• W2885702325 sameAs 2885702325 @default.
• W2885702325 citedByCount "0" @default.
• W2885702325 crossrefType "journal-article" @default.
• W2885702325 hasAuthorship W2885702325A5003827108 @default.
• W2885702325 hasAuthorship W2885702325A5006049703 @default.
• W2885702325 hasAuthorship W2885702325A5010407648 @default.
• W2885702325 hasAuthorship W2885702325A5014511041 @default.
• W2885702325 hasAuthorship W2885702325A5018943952 @default.
• W2885702325 hasAuthorship W2885702325A5030498911 @default.
• W2885702325 hasAuthorship W2885702325A5052799646 @default.
• W2885702325 hasAuthorship W2885702325A5061607767 @default.
• W2885702325 hasAuthorship W2885702325A5067739320 @default.
• W2885702325 hasAuthorship W2885702325A5081455161 @default.
• W2885702325 hasConcept C104317684 @default.
• W2885702325 hasConcept C126322002 @default.
• W2885702325 hasConcept C127561419 @default.
• W2885702325 hasConcept C134018914 @default.
• W2885702325 hasConcept C147708747 @default.
• W2885702325 hasConcept C170493617 @default.
• W2885702325 hasConcept C178790620 @default.
• W2885702325 hasConcept C185592680 @default.
• W2885702325 hasConcept C191709040 @default.
• W2885702325 hasConcept C2775960820 @default.
• W2885702325 hasConcept C2776996007 @default.
• W2885702325 hasConcept C2777587049 @default.
• W2885702325 hasConcept C2780394083 @default.
• W2885702325 hasConcept C49418065 @default.
• W2885702325 hasConcept C502942594 @default.
• W2885702325 hasConcept C540031477 @default.
• W2885702325 hasConcept C55493867 @default.
• W2885702325 hasConcept C66400584 @default.
• W2885702325 hasConcept C71924100 @default.
• W2885702325 hasConcept C74373430 @default.
• W2885702325 hasConcept C7836513 @default.
• W2885702325 hasConcept C82867764 @default.
• W2885702325 hasConcept C86803240 @default.
• W2885702325 hasConcept C95444343 @default.
• W2885702325 hasConceptScore W2885702325C104317684 @default.
• W2885702325 hasConceptScore W2885702325C126322002 @default.
• W2885702325 hasConceptScore W2885702325C127561419 @default.
• W2885702325 hasConceptScore W2885702325C134018914 @default.
• W2885702325 hasConceptScore W2885702325C147708747 @default.
• W2885702325 hasConceptScore W2885702325C170493617 @default.
• W2885702325 hasConceptScore W2885702325C178790620 @default.
• W2885702325 hasConceptScore W2885702325C185592680 @default.
• W2885702325 hasConceptScore W2885702325C191709040 @default.
• W2885702325 hasConceptScore W2885702325C2775960820 @default.
• W2885702325 hasConceptScore W2885702325C2776996007 @default.
• W2885702325 hasConceptScore W2885702325C2777587049 @default.
• W2885702325 hasConceptScore W2885702325C2780394083 @default.
• W2885702325 hasConceptScore W2885702325C49418065 @default.
• W2885702325 hasConceptScore W2885702325C502942594 @default.
• W2885702325 hasConceptScore W2885702325C540031477 @default.
• W2885702325 hasConceptScore W2885702325C55493867 @default.
• W2885702325 hasConceptScore W2885702325C66400584 @default.
• W2885702325 hasConceptScore W2885702325C71924100 @default.
• W2885702325 hasConceptScore W2885702325C74373430 @default.
• W2885702325 hasConceptScore W2885702325C7836513 @default.
• W2885702325 hasConceptScore W2885702325C82867764 @default.
• W2885702325 hasConceptScore W2885702325C86803240 @default.
• W2885702325 hasConceptScore W2885702325C95444343 @default.
• W2885702325 hasLocation W28857023251 @default.
• W2885702325 hasOpenAccess W2885702325 @default.
• W2885702325 hasPrimaryLocation W28857023251 @default.
• W2885702325 hasRelatedWork W101606460 @default.
• W2885702325 hasRelatedWork W134854448 @default.
• W2885702325 hasRelatedWork W1970237948 @default.
• W2885702325 hasRelatedWork W1977131799 @default.
• W2885702325 hasRelatedWork W1981550662 @default.
• W2885702325 hasRelatedWork W1999150574 @default.
• W2885702325 hasRelatedWork W2010928511 @default.
• W2885702325 hasRelatedWork W2040180103 @default.
• W2885702325 hasRelatedWork W2091727170 @default.
• W2885702325 hasRelatedWork W2093072827 @default.
• W2885702325 hasRelatedWork W2135568436 @default.
• W2885702325 hasRelatedWork W2320550441 @default.
• W2885702325 hasRelatedWork W2419175081 @default.
• W2885702325 hasRelatedWork W2574703584 @default.
• W2885702325 hasRelatedWork W2622649031 @default.
• W2885702325 hasRelatedWork W2885642885 @default.
• W2885702325 hasRelatedWork W2885801900 @default.
• W2885702325 hasRelatedWork W2899291691 @default.
• W2885702325 hasRelatedWork W2956177012 @default.

• next