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- W2885855523 abstract "BackgroundSuccessful treatment is an essential aspect of tuberculosis (TB) elimination and prevention against drug resistance. The loss to follow up, and treatment failure is the main causes of poor treatment outcome. To prevent these causes from hindering successful treatment of TB patient and increase adherence to treatment, Community Based Directly Observed Treatment Short course (CB DOTS) program are being promoted. This study aims to compare programmatic treatment outcome for all new TB cases registered in Community Based DOTS and Facility-Based DOTS (FB DOTS) program in districts of Nepal.MethodologyAnalysis of secondary data was carried out to document the outcome of TB patients registered in 2015-16 in terms of success, loss to follow up, treatment failure, and death for CB DOTS in eleven districts of Nepal using publicly available data. Each CB DOTS district was then matched with 11 FB DOTS district to compare the outcomes. The selection was based on pre-decided criteria like districts from similar geographies, population, and same ecology.FindingDistricts in which community-based DOTS was implemented showed better median treatment success rate (92.88%) than facility-based DOTS implemented districts (89.84%) (p = 0.02). The median loss to follow up the rate of community-based DOTS implemented districts (0.92%) was better than the median loss to follow uprate of facility-based DOTS implemented districts (2.967%) (p = 0.02).ConclusionCompared to the Facility-Based DOTS, Community Based DOTS approach was found to be more effective in terms of treatment outcome and adherence to treatment. Community-based treatment is a patient-centered approach for tuberculosis treatment and is found to be more useful to achieve high treatment success rate in countries like Nepal that have rough terrain and limited connectivity to some regions." @default.
- W2885855523 created "2018-08-22" @default.
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- W2885855523 date "2019-09-01" @default.
- W2885855523 modified "2023-09-27" @default.
- W2885855523 title "Community and facility-based tuberculosis control: Programmatic comparison and experience from Nepal" @default.
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- W2885855523 doi "https://doi.org/10.1016/j.cegh.2018.08.006" @default.
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