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- W2885934840 abstract "In the present work the physical-chemical and energetic properties of the molecules of hydrogels about chitosan crosslinking with genipin were studied in the adsorption process of Metformine and Glibenclamide. The analysis was done by means of PM6 model in order to obtain the necessary data base to establish their potential use as transdermal controlled release systems. Currently, the drugs (metformine and glibenclamide) are administered orally, however, there are already several oral medications that have been presented as transdermal administration systems (SAT), with great advantages, such as patient comfort and zero order release. Drugs before mentioned, are especially important in chronic diseases such as type 2 diabetes." @default.
- W2885934840 created "2018-08-22" @default.
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- W2885934840 date "2018-04-09" @default.
- W2885934840 modified "2023-10-17" @default.
- W2885934840 title "Study of the Adsorption of Glibenclamide/Metformine in Hydrogels Using PM6 Model" @default.
- W2885934840 doi "https://doi.org/10.1115/dmd2018-6935" @default.
- W2885934840 hasPublicationYear "2018" @default.
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