Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886117407> ?p ?o ?g. }
- W2886117407 endingPage "e12586" @default.
- W2886117407 startingPage "e12586" @default.
- W2886117407 abstract "In order to discover the bioactive metabolites of Pyrus ussuriensis Maxim, the systematic chemical and pharmacological investigations were performed. The ethyl acetate extract of the plant displayed activities against ear edema in mice, with an inhibition rate of 17.1%, at a dose of 400mg/kg in vivo. Meanwhile, the ethyl acetate extract showed the best apophlegmatic (inhibition: 49.9%) and antitussive effects (inhibition: 34%) at 800mg/kg in vivo tests, and inhibition of NO production (IC50=0.06 μg/mL). Subsequently, twelve compounds were isolated from the ethyl acetate extract and identified as friedelin (1), daucosterol (2), β-sitosterol (3), betulinic acid (4), oleanolic acid (5), ursolic acid (6), 2-O-buty-1-O’-(2-ethylhexyl) benzene-1,8-dicarboxylate (7), Narcissin (8), 3-hydroxy-3-carboxyl-glutaric acid dimethyl ester (9), 2-hydroxyl -butanediol icacid-4-methyleste (10), myristic acid (11), and (Z)-11-hexadecen-1-ol acetate (12). Among them, compounds 1, 2, 4, 5, 6, and 11 exhibited moderate indirect inhibitory effects on lipopolysaccharide-induced NO and TNF-α production. Practical applications Pyrus ussuriensis Maxim is an edible and medical fruit with many functional properties. Unfortunately, few literatures about bioactive components of this fruit have been investigated. The result indicated that P. ussuriensis have obvious anti-inflammatory, antitussive, and apophlegmatic activities, which were associated with the folk uses of this fruit. Furthermore, this work also suggests a potential use of P. ussuriensis as an important source of natural anti-inflammatory agents and they may also be considered as a functional food." @default.
- W2886117407 created "2018-08-22" @default.
- W2886117407 creator A5034366062 @default.
- W2886117407 creator A5058087359 @default.
- W2886117407 creator A5074942308 @default.
- W2886117407 creator A5076162565 @default.
- W2886117407 creator A5082605046 @default.
- W2886117407 date "2018-07-29" @default.
- W2886117407 modified "2023-10-13" @default.
- W2886117407 title "Chemical components and bioactivity evaluation of extracts from pear (<i>Pyrus Ussuriensis</i>Maxim) fruit" @default.
- W2886117407 cites W1901901684 @default.
- W2886117407 cites W1964159726 @default.
- W2886117407 cites W1967865536 @default.
- W2886117407 cites W1977555733 @default.
- W2886117407 cites W1994902384 @default.
- W2886117407 cites W1999693385 @default.
- W2886117407 cites W2015247449 @default.
- W2886117407 cites W2023311625 @default.
- W2886117407 cites W2024080368 @default.
- W2886117407 cites W2025188710 @default.
- W2886117407 cites W2032596085 @default.
- W2886117407 cites W2058911550 @default.
- W2886117407 cites W2060840488 @default.
- W2886117407 cites W2074365554 @default.
- W2886117407 cites W2082488224 @default.
- W2886117407 cites W2133439754 @default.
- W2886117407 cites W2138475078 @default.
- W2886117407 cites W2334107942 @default.
- W2886117407 cites W2509388627 @default.
- W2886117407 cites W2585311295 @default.
- W2886117407 cites W2622546133 @default.
- W2886117407 cites W2738417396 @default.
- W2886117407 cites W2740867618 @default.
- W2886117407 cites W2751502334 @default.
- W2886117407 cites W6719106 @default.
- W2886117407 doi "https://doi.org/10.1111/jfbc.12586" @default.
- W2886117407 hasPublicationYear "2018" @default.
- W2886117407 type Work @default.
- W2886117407 sameAs 2886117407 @default.
- W2886117407 citedByCount "3" @default.
- W2886117407 countsByYear W28861174072020 @default.
- W2886117407 countsByYear W28861174072021 @default.
- W2886117407 countsByYear W28861174072022 @default.
- W2886117407 crossrefType "journal-article" @default.
- W2886117407 hasAuthorship W2886117407A5034366062 @default.
- W2886117407 hasAuthorship W2886117407A5058087359 @default.
- W2886117407 hasAuthorship W2886117407A5074942308 @default.
- W2886117407 hasAuthorship W2886117407A5076162565 @default.
- W2886117407 hasAuthorship W2886117407A5082605046 @default.
- W2886117407 hasBestOaLocation W28861174071 @default.
- W2886117407 hasConcept C150903083 @default.
- W2886117407 hasConcept C185592680 @default.
- W2886117407 hasConcept C207001950 @default.
- W2886117407 hasConcept C2775874295 @default.
- W2886117407 hasConcept C2777829905 @default.
- W2886117407 hasConcept C2779513101 @default.
- W2886117407 hasConcept C2779700632 @default.
- W2886117407 hasConcept C2779858419 @default.
- W2886117407 hasConcept C2994380890 @default.
- W2886117407 hasConcept C31903555 @default.
- W2886117407 hasConcept C43617362 @default.
- W2886117407 hasConcept C54355233 @default.
- W2886117407 hasConcept C55493867 @default.
- W2886117407 hasConcept C556039675 @default.
- W2886117407 hasConcept C59822182 @default.
- W2886117407 hasConcept C71924100 @default.
- W2886117407 hasConcept C86803240 @default.
- W2886117407 hasConceptScore W2886117407C150903083 @default.
- W2886117407 hasConceptScore W2886117407C185592680 @default.
- W2886117407 hasConceptScore W2886117407C207001950 @default.
- W2886117407 hasConceptScore W2886117407C2775874295 @default.
- W2886117407 hasConceptScore W2886117407C2777829905 @default.
- W2886117407 hasConceptScore W2886117407C2779513101 @default.
- W2886117407 hasConceptScore W2886117407C2779700632 @default.
- W2886117407 hasConceptScore W2886117407C2779858419 @default.
- W2886117407 hasConceptScore W2886117407C2994380890 @default.
- W2886117407 hasConceptScore W2886117407C31903555 @default.
- W2886117407 hasConceptScore W2886117407C43617362 @default.
- W2886117407 hasConceptScore W2886117407C54355233 @default.
- W2886117407 hasConceptScore W2886117407C55493867 @default.
- W2886117407 hasConceptScore W2886117407C556039675 @default.
- W2886117407 hasConceptScore W2886117407C59822182 @default.
- W2886117407 hasConceptScore W2886117407C71924100 @default.
- W2886117407 hasConceptScore W2886117407C86803240 @default.
- W2886117407 hasIssue "5" @default.
- W2886117407 hasLocation W28861174071 @default.
- W2886117407 hasOpenAccess W2886117407 @default.
- W2886117407 hasPrimaryLocation W28861174071 @default.
- W2886117407 hasRelatedWork W2054206985 @default.
- W2886117407 hasRelatedWork W2065952104 @default.
- W2886117407 hasRelatedWork W2067741132 @default.
- W2886117407 hasRelatedWork W2073306490 @default.
- W2886117407 hasRelatedWork W2117620352 @default.
- W2886117407 hasRelatedWork W2155682384 @default.
- W2886117407 hasRelatedWork W2170751444 @default.
- W2886117407 hasRelatedWork W2756354275 @default.
- W2886117407 hasRelatedWork W3195907093 @default.
- W2886117407 hasRelatedWork W609517664 @default.