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- W2886169771 abstract "We consider a class of viral infection dynamic models with inhibitory effect on the growth of uninfected T cells caused by infected T cells and logistic target cell growth. The basic reproduction number<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:msub><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mn mathvariant=normal>0</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>is derived. It is shown that the uninfected equilibrium is globally asymptotically stable if<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:msub><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mn mathvariant=normal>0</mml:mn></mml:mrow></mml:msub><mml:mo><</mml:mo><mml:mn mathvariant=normal>1</mml:mn></mml:math>. Sufficient conditions for the existence of Hopf bifurcation at the infected equilibrium are investigated by analyzing the distribution of eigenvalues. Furthermore, the properties of Hopf bifurcation are determined by the normal form theory and the center manifold. Numerical simulations are carried out to support the theoretical analysis." @default.
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- W2886169771 date "2018-08-12" @default.
- W2886169771 modified "2023-10-18" @default.
- W2886169771 title "Modeling Inhibitory Effect on the Growth of Uninfected T Cells Caused by Infected T Cells: Stability and Hopf Bifurcation" @default.
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- W2886169771 doi "https://doi.org/10.1155/2018/3176893" @default.
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