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- W2886373018 abstract "Two bacterial diterpene synthases from the actinomycete Allokutzneria albata were investigated, resulting in the identification of the structurally unprecedented compound spiroalbatene from the first and cembrene A from the second enzyme. Both enzymes were thoroughly investigated in terms of their mechanisms by isotope labeling experiments, site-directed mutagenesis, and variation of the metal cofactors and pH value. For spiroalbatene synthase, the pH- and Mn2+ -dependent formation of the side product thunbergol was observed, which is biosynthetically linked to spiroalbatene." @default.
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- W2886373018 date "2018-02-21" @default.
- W2886373018 modified "2023-10-17" @default.
- W2886373018 title "Two Diterpene Synthases for Spiroalbatene and Cembrene A from<i>Allokutzneria albata</i>" @default.
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- W2886373018 doi "https://doi.org/10.1002/anie.201800385" @default.
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