FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886482773> ?p ?o ?g. }

• W2886482773 endingPage "38" @default.
• W2886482773 startingPage "32" @default.
• W2886482773 abstract "The aim of this study was to analyze risk factors for septic complications during adjuvant chemotherapy and their impact on survival in patients with advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS).We retrospectively reviewed the medical records of 69 patients with advanced epithelial ovarian cancer from 2004 to 2017. All patients underwent three cycles of NACT followed by IDS and adjuvant chemotherapy. We identified grade 3 or 4 hematologic complications and severe adverse events accompanied by neutropenia, including sepsis or septic shock, that occurred during treatment. Clinicopathologic data including demographic factors, preoperative medical conditions, surgical procedures, and survival times were evaluated.Of 69 patients, 27 (39.1%), 6 (8.8%), and 2 (2.9%) patients experienced grade 3 or 4 neutropenia, anemia, and thrombocytopenia, respectively, during NACT. Thirteen patients (18.8%) had a neutropenic fever with sepsis and 2 patients (2.9%) died of septic shock during adjuvant chemotherapy. Concurrent medical disease, splenectomy during IDS, and anemia or thrombocytopenia during NACT were significant risk factors for septic adverse events. In multivariate analysis, anemia (hemoglobin < 8 g/dL, p = 0.004) during NACT was the only significant factor associated with septic adverse events during adjuvant chemotherapy. Although there was no significant difference in progression-free survival, overall survival was significantly shorter in patients with septic adverse events (median, 82.3 vs. 17.3 months, p = 0.007).Grade 3 anemia during NACT may be an early indicator for septic adverse events during adjuvant chemotherapy. Considering the adverse impact on survival, scheme and dose of adjuvant chemotherapy should be tailored, and careful follow-up evaluation should be ensured in this patient group." @default.
• W2886482773 created "2018-08-22" @default.
• W2886482773 creator A5004587587 @default.
• W2886482773 creator A5009862143 @default.
• W2886482773 creator A5030481456 @default.
• W2886482773 creator A5033913977 @default.
• W2886482773 creator A5039595887 @default.
• W2886482773 creator A5071045682 @default.
• W2886482773 creator A5079968599 @default.
• W2886482773 date "2018-10-01" @default.
• W2886482773 modified "2023-10-01" @default.
• W2886482773 title "Risk factors for septic adverse events and their impact on survival in advanced ovarian cancer patients treated with neoadjuvant chemotherapy and interval debulking surgery" @default.
• W2886482773 cites W1956340193 @default.
• W2886482773 cites W2003812420 @default.
• W2886482773 cites W2008668845 @default.
• W2886482773 cites W2009097203 @default.
• W2886482773 cites W2009263734 @default.
• W2886482773 cites W2012171803 @default.
• W2886482773 cites W2037605675 @default.
• W2886482773 cites W2086527623 @default.
• W2886482773 cites W2092771702 @default.
• W2886482773 cites W2120388840 @default.
• W2886482773 cites W2120840826 @default.
• W2886482773 cites W2125894404 @default.
• W2886482773 cites W2131630923 @default.
• W2886482773 cites W2138035969 @default.
• W2886482773 cites W2138820856 @default.
• W2886482773 cites W2161107831 @default.
• W2886482773 cites W2163830215 @default.
• W2886482773 cites W2167447108 @default.
• W2886482773 cites W2170199384 @default.
• W2886482773 cites W2200242714 @default.
• W2886482773 cites W2223663708 @default.
• W2886482773 cites W2271925942 @default.
• W2886482773 cites W2280404143 @default.
• W2886482773 cites W2405810353 @default.
• W2886482773 cites W2416729954 @default.
• W2886482773 cites W2506186937 @default.
• W2886482773 cites W2570618306 @default.
• W2886482773 doi "https://doi.org/10.1016/j.ygyno.2018.08.009" @default.
• W2886482773 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30122310" @default.
• W2886482773 hasPublicationYear "2018" @default.
• W2886482773 type Work @default.
• W2886482773 sameAs 2886482773 @default.
• W2886482773 citedByCount "4" @default.
• W2886482773 countsByYear W28864827732018 @default.
• W2886482773 countsByYear W28864827732020 @default.
• W2886482773 countsByYear W28864827732022 @default.
• W2886482773 crossrefType "journal-article" @default.
• W2886482773 hasAuthorship W2886482773A5004587587 @default.
• W2886482773 hasAuthorship W2886482773A5009862143 @default.
• W2886482773 hasAuthorship W2886482773A5030481456 @default.
• W2886482773 hasAuthorship W2886482773A5033913977 @default.
• W2886482773 hasAuthorship W2886482773A5039595887 @default.
• W2886482773 hasAuthorship W2886482773A5071045682 @default.
• W2886482773 hasAuthorship W2886482773A5079968599 @default.
• W2886482773 hasConcept C121608353 @default.
• W2886482773 hasConcept C126322002 @default.
• W2886482773 hasConcept C141071460 @default.
• W2886482773 hasConcept C197934379 @default.
• W2886482773 hasConcept C2776694085 @default.
• W2886482773 hasConcept C2777063308 @default.
• W2886482773 hasConcept C2777628635 @default.
• W2886482773 hasConcept C2778248108 @default.
• W2886482773 hasConcept C2778384902 @default.
• W2886482773 hasConcept C2780427987 @default.
• W2886482773 hasConcept C2780873365 @default.
• W2886482773 hasConcept C2781100745 @default.
• W2886482773 hasConcept C71924100 @default.
• W2886482773 hasConceptScore W2886482773C121608353 @default.
• W2886482773 hasConceptScore W2886482773C126322002 @default.
• W2886482773 hasConceptScore W2886482773C141071460 @default.
• W2886482773 hasConceptScore W2886482773C197934379 @default.
• W2886482773 hasConceptScore W2886482773C2776694085 @default.
• W2886482773 hasConceptScore W2886482773C2777063308 @default.
• W2886482773 hasConceptScore W2886482773C2777628635 @default.
• W2886482773 hasConceptScore W2886482773C2778248108 @default.
• W2886482773 hasConceptScore W2886482773C2778384902 @default.
• W2886482773 hasConceptScore W2886482773C2780427987 @default.
• W2886482773 hasConceptScore W2886482773C2780873365 @default.
• W2886482773 hasConceptScore W2886482773C2781100745 @default.
• W2886482773 hasConceptScore W2886482773C71924100 @default.
• W2886482773 hasIssue "1" @default.
• W2886482773 hasLocation W28864827731 @default.
• W2886482773 hasLocation W28864827732 @default.
• W2886482773 hasOpenAccess W2886482773 @default.
• W2886482773 hasPrimaryLocation W28864827731 @default.
• W2886482773 hasRelatedWork W1981507940 @default.
• W2886482773 hasRelatedWork W1992919388 @default.
• W2886482773 hasRelatedWork W1999706042 @default.
• W2886482773 hasRelatedWork W2065800215 @default.
• W2886482773 hasRelatedWork W2133480631 @default.
• W2886482773 hasRelatedWork W2364106504 @default.
• W2886482773 hasRelatedWork W2409812054 @default.
• W2886482773 hasRelatedWork W3035298936 @default.
• W2886482773 hasRelatedWork W3097676887 @default.
• W2886482773 hasRelatedWork W59268075 @default.
• W2886482773 hasVolume "151" @default.

• next